2022
Protein nanowires with tunable functionality and programmable self-assembly using sequence-controlled synthesis
Shapiro DM, Mandava G, Yalcin SE, Arranz-Gibert P, Dahl PJ, Shipps C, Gu Y, Srikanth V, Salazar-Morales AI, O’Brien J, Vanderschuren K, Vu D, Batista VS, Malvankar NS, Isaacs FJ. Protein nanowires with tunable functionality and programmable self-assembly using sequence-controlled synthesis. Nature Communications 2022, 13: 829. PMID: 35149672, PMCID: PMC8837800, DOI: 10.1038/s41467-022-28206-x.Peer-Reviewed Original ResearchConceptsProtein nanowiresElectronic functionalityChemical-based synthesisConductive protein nanowiresSequence-controlled synthesisHigh electronic conductivityGold nanoparticlesSite-specific conjugationSynthetic chemistryTunable functionalityElectronic conductivityTunable propertiesAttractive biomaterialNonstandard amino acidsSynthetic biologyNanowiresBiomaterialsProtein materialSynthesisAtomic structureMost biomaterialsIncorporation of tryptophanFunctionalityConductivityNanoparticles
2020
Electric field stimulates production of highly conductive microbial OmcZ nanowires
Yalcin SE, O’Brien J, Gu Y, Reiss K, Yi SM, Jain R, Srikanth V, Dahl PJ, Huynh W, Vu D, Acharya A, Chaudhuri S, Varga T, Batista VS, Malvankar NS. Electric field stimulates production of highly conductive microbial OmcZ nanowires. Nature Chemical Biology 2020, 16: 1136-1142. PMID: 32807967, PMCID: PMC7502555, DOI: 10.1038/s41589-020-0623-9.Peer-Reviewed Original ResearchConceptsConductive protein nanowiresIndividual nanowiresProtein nanowiresElectronic functionalityNanowiresElectric fieldGeobacter sulfurreducens biofilmsHigh conductivityMost natural materialsHigh stiffnessElectrical signalsBidirectional interfaceElectronic systemsLiving materialsNatural materialsΠ stackingSpectroscopic studiesEnergy productionNanospectroscopyConductivityStiffnessConformational switchingΒ-sheetHeme groupSensing