2024
Early goal enteral nutrition associated with decreased in-hospital death in mechanically ventilated critically ill adults: a retrospective cohort study
Powierza C, Doyle M, Wasden K, Intihar T, Korwin A, Honiden S, Knauert M. Early goal enteral nutrition associated with decreased in-hospital death in mechanically ventilated critically ill adults: a retrospective cohort study. BMJ Open Respiratory Research 2024, 11: e001962. PMID: 38749534, PMCID: PMC11097881, DOI: 10.1136/bmjresp-2023-001962.Peer-Reviewed Original ResearchConceptsEarly enteral nutritionIn-hospital deathCritically ill adultsRetrospective cohort studyDays of intubationEnteral nutritionIll adultsAdult patientsCohort studyAssociated with decreased in-hospital deathsMechanically ventilated critically ill adultsGoal enteral nutritionIncreased hospital dischargeInitiation of ENCritically ill adult patientsMechanically ventilated adult patientsIncidence of in-hospital deathMedical intensive care unitAssociated with significant improvementsIll adult patientsDose of ENIntensive care unitClinical outcomesImprove mortalityPrimary outcome
2008
Early versus late intravenous insulin administration in critically ill patients
Honiden S, Schultz A, Im SA, Nierman DM, Gong MN. Early versus late intravenous insulin administration in critically ill patients. Intensive Care Medicine 2008, 34: 881. PMID: 18180902, PMCID: PMC2486366, DOI: 10.1007/s00134-007-0978-3.Peer-Reviewed Original ResearchConceptsIntensive insulin therapyHospital mortalityICU admissionEarly therapyEarly intensive insulin therapyMore ventilator-free daysDecreased hospital mortalityLower ICU mortalityShorter ICU stayVentilator-free daysLower hospital mortalityProspective cohort studyShorter hospital stayTertiary teaching hospitalIntravenous insulin administrationPatientsThe studyAdmission diagnosisHospital stayICU mortalityICU stayCohort studyInsulin therapyMedical ICUDirection of associationIll patients