2023
Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5
Chen Y, Su H, Zhao J, Na Z, Jiang K, Bacchiocchi A, Loh K, Halaban R, Wang Z, Cao X, Slavoff S. Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5. Cell Reports 2023, 42: 113145. PMID: 37725512, PMCID: PMC10629662, DOI: 10.1016/j.celrep.2023.113145.Peer-Reviewed Original ResearchConceptsG2/M phaseWD40-repeat protein WDR5Mitotic spindle lengthMultiple interaction partnersM phaseOff-target genesLate G1 phaseWDR5 interactionMitotic functionsH3K4me3 levelsWDR5Interaction partnersMultiple proteinsExpression maximaCell cycleSpindle lengthG1 phaseGenesCell proliferationOff-target bindingBindingInteractomeChromatinTranscriptionKIF2A.
1988
Paracrine Stimulation of Melanocytes by Keratinocytes through Basic Fibroblast Growth Factora
HALABAN R, LANGDON R, BIRCHALL N, CCUONO C, BAIRD A, SCOTT G, MOELLOMANN G, MCGUIRE J. Paracrine Stimulation of Melanocytes by Keratinocytes through Basic Fibroblast Growth Factora. Annals Of The New York Academy Of Sciences 1988, 548: 180-190. PMID: 2470294, DOI: 10.1111/j.1749-6632.1988.tb18805.x.Peer-Reviewed Original ResearchConceptsBasic fibroblast growth factorBFGF gene transcriptsGrowth factorNormal human melanocytesGene transcriptsFibroblast growth factorNatural growth factorsNorthern blotHuman melanocytesMelanocyte mitogensMelanocyte growthParacrine stimulationMelanocytesHuman keratinocytesSynthetic peptidesKeratinocytesUltraviolet BTranscriptsPresence of keratinocytesMitogenBindingBlotProliferationMonophosphateBasic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.
Halaban R, Langdon R, Birchall N, Cuono C, Baird A, Scott G, Moellmann G, McGuire J. Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes. Journal Of Cell Biology 1988, 107: 1611-1619. PMID: 2459134, PMCID: PMC2115244, DOI: 10.1083/jcb.107.4.1611.Peer-Reviewed Original ResearchConceptsBasic fibroblast growth factorFibroblast growth factorBFGF gene transcriptsHuman melanocytesGrowth factorNormal human melanocytesNatural mitogenHuman keratinocytesGene transcriptsNatural growth factorsNorthern blotMelanocyte mitogensMelanocyte growthMelanocytesPure culturePresence of serumMitogenSynthetic peptidesKeratinocytesCellsCAMPTranscriptsPresence of keratinocytesBindingBlot