2022
Exercise, Diet, and Weight Management During Cancer Treatment: ASCO Guideline
Ligibel JA, Bohlke K, May AM, Clinton SK, Demark-Wahnefried W, Gilchrist SC, Irwin ML, Late M, Mansfield S, Marshall TF, Meyerhardt JA, Thomson CA, Wood WA, Alfano CM. Exercise, Diet, and Weight Management During Cancer Treatment: ASCO Guideline. Journal Of Clinical Oncology 2022, 40: 2491-2507. PMID: 35576506, DOI: 10.1200/jco.22.00687.Peer-Reviewed Original ResearchConceptsWeight loss interventionCancer treatmentSystematic reviewNeutropenic dietPreoperative exerciseLoss interventionActive treatmentResistance exerciseLung cancerWeight managementActive cancer treatmentIntentional weight lossPatient-reported outcomesRisk of infectionQuality of lifeTypes of cancerCurative intentASCO guidelinesHospital stayPostoperative lengthTreatment toxicityOncology providersAdvanced cancerCochrane LibraryCardiorespiratory fitnessLetter to the Editor: Differentiating Between Intentional Versus Unintentional Weight Loss.
Puklin L, Irwin ML, Sanft T, Ferrucci LM. Letter to the Editor: Differentiating Between Intentional Versus Unintentional Weight Loss. Journal Of The National Comprehensive Cancer Network 2022, 20: xliv. PMID: 34991074, DOI: 10.6004/jnccn.2021.7052.Peer-Reviewed Original ResearchHumansWeight Loss
2021
The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention
Delahanty LM, Wadden TA, Goodwin PJ, Alfano CM, Thomson CA, Irwin ML, Neuhouser ML, Crane TE, Frank E, Spears PA, Gillis BP, Hershman DL, Paskett ED, Hopkins J, Bernstein V, Stearns V, White J, Hudis C, Winer EP, Carey L, Partridge AH, Ligibel JA. The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention. Obesity 2021, 30: 28-38. PMID: 34932888, PMCID: PMC9186690, DOI: 10.1002/oby.23287.Peer-Reviewed Original ResearchConceptsWeight loss interventionWeight loss trialLifestyle interventionHealth education materialsWeight lossLoss trialPhysical activityInvasive disease-free survivalDisease-free survivalBreast cancer patientsBreast cancer diagnosisCare of thousandsEducation materialsBaseline weightCancer outcomesCancer patientsHealth coachesCancer recurrenceBreast cancerCaloric restrictionStage IITrialsCancer diagnosisInterventionWomenEffect of the Lifestyle, Exercise, and Nutrition (LEAN) Study on Long-Term Weight Loss Maintenance in Women with Breast Cancer
Lisevick A, Cartmel B, Harrigan M, Li F, Sanft T, Fogarasi M, Irwin ML, Ferrucci LM. Effect of the Lifestyle, Exercise, and Nutrition (LEAN) Study on Long-Term Weight Loss Maintenance in Women with Breast Cancer. Nutrients 2021, 13: 3265. PMID: 34579142, PMCID: PMC8469752, DOI: 10.3390/nu13093265.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsLong-term weight loss maintenanceUsual care groupWeight loss maintenanceCancer survivorsStudy completionCare groupLoss maintenanceWeight lossBody weightLong-term weight maintenanceShort-term weight lossLong-term weight gainModest weight lossOverweight/obesityElectronic health recordsLifestyle interventionWeight maintenanceBreast cancerWeight trajectoriesWeight gainCurve analysisNutrition studiesWeight changeHealth recordsExamining the effect of obesity-associated gene variants on breast cancer survivors in a randomized weight loss intervention
Nguyen T, Irwin ML, Dewan AT, Cartmel B, Harrigan M, Ferrucci LM, Sanft T, Li F, Lu L, Salinas YD. Examining the effect of obesity-associated gene variants on breast cancer survivors in a randomized weight loss intervention. Breast Cancer Research And Treatment 2021, 187: 487-497. PMID: 33677781, DOI: 10.1007/s10549-021-06151-5.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsUsual care groupWeight loss interventionCancer survivorsLoss interventionCare groupFTO rs9939609Percent body fat changesWeight lossMeaningful weight lossBody fat changesBody mass indexObesity-associated gene FTOObesity-associated gene variantsPercent body fatGreater weight lossLifestyle interventionMass indexTreatment armsIntervention groupBreast cancerBody fatFat changesPurposeOur studyHealthy eatingEfficacy of Weight Loss Interventions in United States Active Duty Military Populations: A Systematic Review
Csizmar G, Irwin M. Efficacy of Weight Loss Interventions in United States Active Duty Military Populations: A Systematic Review. Military Medicine 2021, 186: 1093-1099. PMID: 33506251, DOI: 10.1093/milmed/usab012.Peer-Reviewed Original ResearchConceptsDuty service membersActive duty service membersEfficacy of weight loss interventionsWeight loss interventionService membersSystematic reviewActive duty military populationOverseas contingency operationsElectronic databases PubMedPolicy changesNational securityPolicy effortsFood environmentLifestyle interventionUnderdeveloped researchPrevention effortsMilitary populationDoD leadersInclusion criteriaMeasured outcomesMilitary membersDatabases PubMedTarget populationInterventionMember moves
2011
A review of web‐based weight loss interventions in adults
Arem H, Irwin M. A review of web‐based weight loss interventions in adults. Obesity Reviews 2011, 12: e236-e243. PMID: 20804523, PMCID: PMC3086798, DOI: 10.1111/j.1467-789x.2010.00787.x.Peer-Reviewed Original ResearchConceptsWeight lossWeb-based weight loss interventionObesity-related health complicationsWeight loss interventionBurden of diseasePublic health practitionersInternet-delivered interventionsAssociated health consequencesLoss interventionLow adherenceHealthcare costsEfficacious interventionsHealth complicationsObesity ratesControl groupNon-Caucasian participantsHealth consequencesWeight gainHealth practitionersIntervention resultsDefinitive conclusionsPopulation-specific researchPeer-reviewed literatureInterventionMore males
2003
Effect of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women: A Randomized Controlled Trial
Irwin ML, Yasui Y, Ulrich CM, Bowen D, Rudolph RE, Schwartz RS, Yukawa M, Aiello E, Potter JD, McTiernan A. Effect of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women: A Randomized Controlled Trial. JAMA 2003, 289: 323-330. PMID: 12525233, DOI: 10.1001/jama.289.3.323.Peer-Reviewed Original ResearchConceptsSubcutaneous abdominal fatBody fat lossEffects of exercisePostmenopausal womenBody fatBody weightHome-based moderate-intensity exerciseAbdominal fatFat lossGreater body fat lossMajor public health concernSports/recreational activitiesObese postmenopausal womenIntra-abdominal fatPrevalence of obesityReduced body weightDuration of exerciseMin/wkModerate-intensity exerciseSignificant dose responseTotal body fatLevel of exerciseTwelve-month dataPublic health concernExercise group