Delayed Kinetics of IgG, but Not IgA, Antispike Antibodies in Transplant Recipients following SARS-CoV-2 Infection
Cravedi P, Ahearn P, Wang L, Yalamarti T, Hartzell S, Azzi Y, Menon M, Jain A, Billah M, Fernandez-Vina M, Gebel HM, Woodle ES, Haddad NS, Morrison-Porter A, Lee FE, Sanz I, Akalin E, Girnita A, Maltzman JS. Delayed Kinetics of IgG, but Not IgA, Antispike Antibodies in Transplant Recipients following SARS-CoV-2 Infection. Journal Of The American Society Of Nephrology 2021, 32: 3221-3230. PMID: 34599041, PMCID: PMC8638399, DOI: 10.1681/asn.2021040573.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionKidney transplant recipientsTransplant recipientsImmunocompetent controlsSARS-CoV-2 IgASARS-CoV-2 antibodiesTime pointsCross-sectional studyCOVID-19Basis of timingLater time pointsIgG1-4Transplant statusIgA antibodiesIgG responsesIgM responseImmunocompetent individualsPoor outcomeSevere outcomesViral epitopesInfectionIgGRecipientsAntibodiesClass switching