Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against Salmonella
Chen M, Sun H, Boot M, Shao L, Chang SJ, Wang W, Lam TT, Lara-Tejero M, Rego EH, Galán JE. Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against Salmonella. Science 2020, 369: 450-455. PMID: 32703879, PMCID: PMC8020367, DOI: 10.1126/science.aaz1333.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineHost-Pathogen InteractionsHumansHydro-LyasesMiceRab GTP-Binding ProteinsSalmonella entericaSalmonella InfectionsSalmonella typhimuriumSuccinatesVirulence