Featured Publications
Increased complications in geriatric patients with a fracture of the hip whose postoperative weight-bearing is restricted: an analysis of 4918 patients.
Ottesen TD, McLynn RP, Galivanche AR, Bagi PS, Zogg CK, Rubin LE, Grauer JN. Increased complications in geriatric patients with a fracture of the hip whose postoperative weight-bearing is restricted: an analysis of 4918 patients. The Bone & Joint Journal 2018, 100-B: 1377-1384. PMID: 30295535, DOI: 10.1302/0301-620x.100b10.bjj-2018-0489.r1.Peer-Reviewed Original ResearchConceptsWeight-bearing restrictionsLength of stayAdverse eventsPostoperative weight-bearing restrictionsMajor adverse eventsEvidence-based guidelinesBone Joint JOperating theatreMultivariate regression analysisMultivariate oddsFrail patientsThromboembolic eventsElderly patientsHip fractureGeriatric patientsProcedural characteristicsInclusion criteriaPatientsGreater riskProcedural factorsHipReadmissionDeliriumTransfusionSurgery
2021
COVID-positive ankle fracture patients are at increased odds of perioperative surgical complications following open reduction internal fixation surgery
Mercier MR, Galivanche AR, Brand JP, Pathak N, Medvecky MJ, Varthi AG, Rubin LE, Grauer JN. COVID-positive ankle fracture patients are at increased odds of perioperative surgical complications following open reduction internal fixation surgery. PLOS ONE 2021, 16: e0262115. PMID: 34972190, PMCID: PMC8719674, DOI: 10.1371/journal.pone.0262115.Peer-Reviewed Original ResearchConceptsCOVID-positive patientsAnkle fracture surgeryPerioperative adverse eventsAdverse eventsAnkle fracture patientsFracture surgeryFracture patientsOperative interventionAnkle fracturesPropensity matchingCOVID statusOpen reduction internal fixation surgeryPerioperative adverse outcomesPerioperative surgical complicationsMinor adverse eventsPostoperative adverse eventsSerious adverse eventsChronic kidney diseaseCOVID-19 Research DatabaseLong-term outcomesInternal fixation surgeryBasis of agePropensity-score matchingPostoperative complicationsNegative patientsHospital Consumer Assessment of Healthcare Providers and Systems survey response rates are significantly affected by patient characteristics and postoperative outcomes for patients undergoing primary total knee arthroplasty
Mercier MR, Galivanche AR, David WB, Malpani R, Pathak N, Hilibrand AS, Rubin LE, Grauer JN. Hospital Consumer Assessment of Healthcare Providers and Systems survey response rates are significantly affected by patient characteristics and postoperative outcomes for patients undergoing primary total knee arthroplasty. PLOS ONE 2021, 16: e0257555. PMID: 34582475, PMCID: PMC8478166, DOI: 10.1371/journal.pone.0257555.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyPrimary total knee arthroplastyHospital Consumer AssessmentPostoperative outcomesPatient characteristicsHCAHPS survey resultsHCAHPS surveySurvey response rateKnee arthroplastyResponse rateHealthcare providersConsumer AssessmentHigher American SocietyMultivariate regression analysisAnesthesia scorePostoperative variablesTKA patientsAdult patientsPrimary outcomePatient factorsSurgical variablesPatient populationPatient satisfactionSingle institutionHospital experiencePredictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture
Haynes MS, Alder KD, Toombs C, Amakiri IC, Rubin LE, Grauer JN. Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture. JAAOS Global Research And Reviews 2021, 5: e20.00221. PMID: 33989253, PMCID: PMC8133215, DOI: 10.5435/jaaosglobal-d-20-00221.Peer-Reviewed Original ResearchMeSH KeywordsAgedDeliriumHip FracturesHumansMaleMiddle AgedPelvic BonesPostoperative ComplicationsRisk FactorsConceptsHip fracture populationPostoperative deliriumPreoperative dementiaHip fractureGeriatric hip fracture populationDependent functional statusFracture populationAdverse postoperative outcomesHigher American SocietyIndependent risk factorPostoperative adverse outcomesGeriatric patient populationNongeneral anesthesiaPreoperative diabetesPostoperative outcomesIndependent predictorsMale sexAdverse outcomesPatient populationFunctional statusRevision surgeryRisk factorsDeliriumHigher oddsRisk subpopulationsLong-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery.
Kebaish KJ, Galivanche AR, Varthi AG, Ottesen TD, Rubin LE, Grauer JN. Long-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery. Orthopedics 2021, 44: 172-179. PMID: 34039214, DOI: 10.3928/01477447-20210416-01.Peer-Reviewed Original ResearchConceptsLong-term corticosteroid usePosterior lumbar spine surgeryPosterior lumbar surgeryLumbar spine surgeryPerioperative adverse outcomesCorticosteroid useAdverse eventsLumbar surgerySpine surgeryPropensity matchingAdverse outcomesNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMinor adverse eventsEffect of immunosuppressionImprovement Program databaseLong-term corticosteroidsSerious adverse eventsBody mass indexMultiple surgical specialtiesAnesthesiologists classComparable patientsPerioperative outcomesSurgical factorsMore patients
2020
Patients' and Physicians' Knowledge of Radiation Exposure Related to Spine Surgery.
Scott MC, Galivanche AR, Mets EJ, Pathak N, Kahan JB, Burroughs PJ, Varthi AG, Rubin LE, Grauer JN. Patients' and Physicians' Knowledge of Radiation Exposure Related to Spine Surgery. Spine 2020, 45: e1507-e1515. PMID: 32858741, DOI: 10.1097/brs.0000000000003650.Peer-Reviewed Original ResearchConceptsSpine surgeryMagnetic resonance imagingRadiation exposureOutpatient settingPhysicians' knowledgeLumbar radiographsO-armCT imagingIntraoperative radiation exposureCross-sectional imagingCross-sectional surveyPhysician estimatesSpine proceduresBACKGROUND DATACare settingsIntraoperative fluoroscopyLumbar imagingPatientsSurgeryResonance imagingIntraoperative CTSurgeonsAwareness/knowledgeIntraoperative imagingRobotic spine surgeryCoagulopathies Are a Risk Factor for Adverse Events Following Total Hip and Total Knee Arthroplasty.
Malpani R, Mclynn RP, Bovonratwet P, Bagi PS, Yurter A, Mercier MR, Rubin LE, Grauer JN. Coagulopathies Are a Risk Factor for Adverse Events Following Total Hip and Total Knee Arthroplasty. Orthopedics 2020, 43: 233-238. PMID: 32674174, DOI: 10.3928/01477447-20200624-02.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overArthroplasty, Replacement, HipArthroplasty, Replacement, KneeBlood Coagulation DisordersDatabases, FactualFemaleHumansMaleMiddle AgedMultivariate AnalysisOutcome Assessment, Health CarePatient ReadmissionPostoperative ComplicationsRetrospective StudiesRisk FactorsYoung AdultConceptsHigher international normalized ratioInternational normalized ratioMajor adverse eventsTotal hip arthroplastyPartial thromboplastin timeHigher partial thromboplastin timeMinor adverse eventsAdverse eventsLow plateletsHematological conditionsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseTotal knee arthroplasty (TKA) populationQuality Improvement Program databasePrimary total hip arthroplastyDependent functional statusImprovement Program databasePostsurgical adverse eventsTotal knee arthroplastyMultiple adverse eventsPreoperative coagulopathyTHA cohortTKA groupTKA patientsHospital readmissionPostoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications.
Galivanche AR, Kebaish KJ, Adrados M, Ottesen TD, Varthi AG, Rubin LE, Grauer JN. Postoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications. Journal Of The American Academy Of Orthopaedic Surgeons 2020, 28: 342-351. PMID: 31567615, DOI: 10.5435/jaaos-d-19-00104.Peer-Reviewed Original ResearchConceptsPostoperative pressure ulcersHip fracture surgeryPostoperative complicationsPressure ulcersRisk factorsPreoperative comorbiditiesFracture surgerySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseGeriatric hip fracture patientsGeriatric hip fracture surgeryQuality Improvement Program databaseMultivariate regressionNSQIP Participant Use FilePreoperative risk factorsHip fracture patientsImprovement Program databaseUrinary tract infectionElevated platelet countInsulin-dependent diabetesParticipant Use FilePressure ulcer developmentQuality Improvement ProgramPostoperative deliriumPostoperative pneumonia
2019
Admission NarxCare Narcotics Scores are not Associated With Adverse Surgical Outcomes or Self-reported Patient Satisfaction Following Elective Spine Surgery.
Galivanche AR, Mercier MR, Adrados M, Pathak N, McLynn RP, Anandasivam NS, Varthi AG, Rubin LE, Grauer JN. Admission NarxCare Narcotics Scores are not Associated With Adverse Surgical Outcomes or Self-reported Patient Satisfaction Following Elective Spine Surgery. Spine 2019, 44: 1515-1522. PMID: 31356498, DOI: 10.1097/brs.0000000000003120.Peer-Reviewed Original ResearchConceptsMultivariate logistic regressionPatient satisfactionAdverse eventsNarcotic scoreSurvey response rateSpine surgeryResponse rateLogistic regressionSelf-reported patient satisfactionElective spine surgeryPreoperative opioid usePostoperative patient satisfactionTime of admissionAdverse surgical outcomesSpine surgery casesHospital Consumer AssessmentHCAHPS survey resultsDifferent narcoticsNarcotic usagePerioperative outcomesNarcotic utilizationOpioid usePatient characteristicsPostoperative outcomesNarcotic groupMatched Cohort Analysis of Total Hip Arthroplasty in Patients With and Without Parkinson’s Disease: Complications, Mortality, Length of Stay, and Hospital Charges
Kleiner JE, Eltorai AEM, Rubin LE, Daniels AH. Matched Cohort Analysis of Total Hip Arthroplasty in Patients With and Without Parkinson’s Disease: Complications, Mortality, Length of Stay, and Hospital Charges. The Journal Of Arthroplasty 2019, 34: s228-s231. PMID: 30982760, DOI: 10.1016/j.arth.2019.03.023.Peer-Reviewed Original ResearchMeSH KeywordsAgedArthroplasty, Replacement, HipCohort StudiesDatabases, FactualFemaleHealth Care CostsHospital ChargesHospital MortalityHospitalizationHumansInpatientsLength of StayLogistic ModelsMaleMiddle AgedOsteoarthritis, HipParkinson DiseasePatient SafetyPostoperative ComplicationsPropensity ScoreRetrospective StudiesUnited StatesConceptsTotal hip arthroplastyLength of stayCharlson Comorbidity IndexPD patientsComplication rateComorbidity indexHospital chargesDisease patientsCohort analysisHip arthroplastyParkinson's diseaseUtilization Project Nationwide Inpatient SampleGreater Charlson Comorbidity IndexHospital complication ratesMatched Cohort AnalysisHospital mortality rateTotal hospital chargesNationwide Inpatient SampleMultivariable logistic regressionCost of hospitalizationYear of admissionParkinson's disease patientsModel of careHospital mortalityControl patients
2018
Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery
Ottesen TD, McLynn RP, Zogg CK, Shultz BN, Ondeck NT, Bovonratwet P, Bellamkonda KS, Rubin LE, Grauer JN. Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery. The Spine Journal 2018, 18: 2033-2042. PMID: 30077772, DOI: 10.1016/j.spinee.2018.04.007.Peer-Reviewed Original ResearchConceptsElective spine surgeryNon-dialysis patientsDialysis-dependent patientsPerioperative adverse eventsAdverse eventsDialysis patientsSpine surgeryUnplanned readmissionCohort studyPatient demographicsRisk factorsNational Surgical Quality Improvement Program databaseRisk-adjusted multivariate regressionsQuality Improvement Program databaseOperating roomDialysis-independent patientsInstitutional cohort studyMinor adverse eventsRetrospective cohort studyElective spinal surgeryImprovement Program databaseIndependent risk factorMajor adverse eventsPercentage of complicationsAdministrative database study
2017
Revision Total Knee Arthroplasty in Octogenarians: An Analysis of 957 Cases
Bovonratwet P, Tyagi V, Ottesen TD, Ondeck NT, Rubin LE, Grauer JN. Revision Total Knee Arthroplasty in Octogenarians: An Analysis of 957 Cases. The Journal Of Arthroplasty 2017, 33: 178-184. PMID: 28844628, DOI: 10.1016/j.arth.2017.07.032.Peer-Reviewed Original ResearchConceptsRevision total knee arthroplastyTotal knee arthroplastyBlood transfusionOctogenarian patientsKnee arthroplastyPatient populationNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseLonger lengthYoung populationHigh rateImprovement Program databaseYoung patient populationNumber of octogenariansLarger patient populationYear oldsHospital stayIntraoperative characteristicsPerioperative complicationsPerioperative coursePropensity matchingAdvanced ageProgram databaseOctogenariansStayReported Litigation Associated With Primary Hip and Knee Arthroplasty
Bokshan SL, Ruttiman RJ, DePasse JM, Eltorai AEM, Rubin LE, Palumbo MA, Daniels AH. Reported Litigation Associated With Primary Hip and Knee Arthroplasty. The Journal Of Arthroplasty 2017, 32: 3573-3577.e1. PMID: 28781019, DOI: 10.1016/j.arth.2017.07.001.Peer-Reviewed Original ResearchConceptsKnee arthroplastyNerve injuryCommon complicationTechnical complicationsPhysician lossTotal joint arthroplastyCauses of litigationMalpractice lawsuitsPrimary hipTotal hipLikely complicationsJoint arthroplastyRetrospective analysisHip arthroplastyComplicationsArthroplasty surgeonsArthroplastyPainPatientsInjuryHipSurgeonsAverage paymentVerdictSearchCasesOutpatient and Inpatient Unicompartmental Knee Arthroplasty Procedures Have Similar Short-Term Complication Profiles
Bovonratwet P, Ondeck NT, Tyagi V, Nelson SJ, Rubin LE, Grauer JN. Outpatient and Inpatient Unicompartmental Knee Arthroplasty Procedures Have Similar Short-Term Complication Profiles. The Journal Of Arthroplasty 2017, 32: 2935-2940. PMID: 28602533, DOI: 10.1016/j.arth.2017.05.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAmbulatory Surgical ProceduresArthroplasty, Replacement, KneeCohort StudiesComorbidityDatabases, FactualFemaleHumansInpatientsLength of StayMaleMiddle AgedOutcome Assessment, Health CareOutpatientsPatient ReadmissionPatient SatisfactionPostoperative ComplicationsPropensity ScoreQuality ImprovementUnited StatesConceptsUnicompartmental knee arthroplastyNational Surgical Quality Improvement Program databaseInpatient Unicompartmental Knee ArthroplastyQuality Improvement Program databaseLength of hospitalImprovement Program databasePerioperative complicationsProgram databaseOutpatient unicompartmental knee arthroplastyShort-term complication profileUnicompartmental knee arthroplasty (UKA) proceduresNational patient populationPerioperative outcome measuresHigh patient satisfactionKnee arthroplasty proceduresPotential confounding factorsInpatient cohortPerioperative outcomesPostdischarge complicationsPatient characteristicsComplication profileOutpatient surgeryPatient populationKnee arthroplastyOutpatient procedureIntraoperative Femur Fracture Risk During Primary Direct Anterior Approach Cementless Total Hip Arthroplasty With and Without a Fracture Table
Cohen EM, Vaughn JJ, Ritterman SA, Eisenson DL, Rubin LE. Intraoperative Femur Fracture Risk During Primary Direct Anterior Approach Cementless Total Hip Arthroplasty With and Without a Fracture Table. The Journal Of Arthroplasty 2017, 32: 2847-2851. PMID: 28511947, DOI: 10.1016/j.arth.2017.04.020.Peer-Reviewed Original ResearchConceptsIntraoperative femur fracturesTotal hip arthroplastyCementless total hip arthroplastyDirect anterior approachFracture tableHip arthroplastyNonfracture patientsDAA total hip arthroplastySurgical technique variationsStatistical differenceFemoral neck fracturesRevision femoral stemFemur fracture riskAnterior approachMale patientsRetrospective reviewNeck fracturesFemur fracturesFracture riskExclusion criteriaPatientsAverage ageHip surgeonsBone hookFemoral implants
2016
Modifiable Risk Factors in Total Joint Arthroplasty: A Pilot Study.
DeFroda SF, Rubin LE, Jenkins DR. Modifiable Risk Factors in Total Joint Arthroplasty: A Pilot Study. Rhode Island Medical Journal 2016, 99: 28-31. PMID: 27128514.Peer-Reviewed Original ResearchConceptsBody mass indexTotal joint arthroplastyRisk factorsJoint arthroplastyLevel III retrospective studiesModifiable risk factorsIndex surgeonMorbid obesityDiabetes mellitusHemoglobin A1cMass indexPoor outcomeRetrospective studyArthroplasty surgeonsRisk reduction strategiesTobacco productsPilot studyReplacement proceduresStudy periodPatientsSurgeryArthroplastySignificant proportionSurgeonsOutcomes
2014
Cost Benefit Analysis of Topical Tranexamic Acid in Primary Total Hip and Knee Arthroplasty
Tuttle JR, Ritterman SA, Cassidy DB, Anazonwu WA, Froehlich JA, Rubin LE. Cost Benefit Analysis of Topical Tranexamic Acid in Primary Total Hip and Knee Arthroplasty. The Journal Of Arthroplasty 2014, 29: 1512-1515. PMID: 24630599, DOI: 10.1016/j.arth.2014.01.031.Peer-Reviewed Original ResearchConceptsTopical tranexamic acidPrimary total hipTranexamic acidTotal hipKnee arthroplastyTopical TXAPostoperative hemoglobinTransfusion rateAdverse eventsRetrospective cohortConsecutive patientsHospital dispositionArthroplasty patientsPrimary hipDelta hemoglobinTransfusion costsHome dispositionNursing facilitiesPatientsHipArthroplastyHemoglobinCohortEarly Catastrophic Failure of Trochanteric Fixation with the Dall-Miles Cable Grip System
Klinge SA, Vopat BG, Daniels AH, Bariteau JT, Rubin LE, Limbird R. Early Catastrophic Failure of Trochanteric Fixation with the Dall-Miles Cable Grip System. The Journal Of Arthroplasty 2014, 29: 1289-1291. PMID: 24529942, DOI: 10.1016/j.arth.2014.01.001.Peer-Reviewed Original ResearchConceptsDall-Miles cable grip systemCable grip systemTrochanteric fixationGreater trochanteric fixationReports of patientsUltimate fixation strengthEarly catastrophic failureOperating room staffCerclage cablesClinical practiceRoom staffFixation strengthGrip systemSurgical instrumentsFixationPatientsFailureOsteotomySurgeons
2013
Primary knee arthrodesis for severe crystalline arthropathy.
Vopat BG, Ritterman SA, Kayiaros S, Rubin LE. Primary knee arthrodesis for severe crystalline arthropathy. The American Journal Of Orthopedics 2013, 42: e91-3. PMID: 24278911.Peer-Reviewed Original ResearchConceptsKnee arthrodesisPain-free kneesPeriarticular soft tissue massesSurgery of choiceSignificant bone lossSoft tissue massMonosodium urate crystalsKnee fusionKnee painInflammatory arthritisPatient factorsBone lossCrystalline arthropathyGouty arthritisLigamentous instabilityUncontrolled goutUrate crystalsDiarthroidal jointsHealth careCommon formArthritisArthrodesisGoutFunctional levelDifficult access
2005
Arterial thrombosis associated with heterozygous factor V Leiden disorder, hyperhomocysteinemia, and peripheral arterial disease: Importance of synergistic factors
Page C, Rubin LE, Gusberg RJ, Dardik A. Arterial thrombosis associated with heterozygous factor V Leiden disorder, hyperhomocysteinemia, and peripheral arterial disease: Importance of synergistic factors. Journal Of Vascular Surgery 2005, 42: 1014-1018. PMID: 16275464, DOI: 10.1016/j.jvs.2005.06.019.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAcute DiseaseAngiographyFactor VFactor V DeficiencyFibrinolytic AgentsFollow-Up StudiesHeparinHeterozygoteHumansHyperhomocysteinemiaInjections, Intra-ArterialMaleMiddle AgedMutationPeripheral Vascular DiseasesPopliteal ArteryThromboembolismThrombolytic TherapyTissue Plasminogen ActivatorConceptsPeripheral arterial diseaseArterial diseaseArterial thrombosisPre-existing peripheral arterial diseaseAcute popliteal artery thrombosisAcute arterial thrombosisPopliteal artery thrombosisIntra-arterial thrombolysisRisk factor modificationDeep venous thrombosisLong-term treatmentFactor V LeidenArtery thrombosisAcute thrombosisVenous thrombosisHomocysteine levelsFactor modificationV LeidenNormal limitsThrombosisHyperhomocysteinemiaFolic acidDiseaseDisordersAnticoagulation