Estimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis
Carey G, Holleck J, Alshaeba S, Jayakrishnan R, Gordon K, Grimshaw A, Gunderson C. Estimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2023, 78: 1150-1159. PMID: 36964648, DOI: 10.1093/jac/dkad078.Peer-Reviewed Original ResearchConceptsCommon infectious syndromesEmpirical antibioticsPrevalence of MRSAInfectious syndromesMRSA infectionIll patientsMortality rateSystematic reviewAbsolute mortality benefitAnti-MRSA therapyEmpirical antibiotic coverageLow-risk infectionsSoft tissue infectionsUrinary tract infectionAbsolute risk reductionMethicillin-resistant Staphylococcus aureusCatheter-related infectionsStudy of patientsBaseline mortality ratesSystematic literature searchWeb of ScienceMRSA coverageAntibiotic coverageEmpirical antimicrobialsMortality benefitProviding Structured Real-Time Feedback on Postdischarge Outcomes Using Electronic Health Record Data
Zegarek M, Holleck J, Merchant N, Windish D, Hay S. Providing Structured Real-Time Feedback on Postdischarge Outcomes Using Electronic Health Record Data. Southern Medical Journal 2023, 116: 305-311. PMID: 36863053, DOI: 10.14423/smj.0000000000001522.Peer-Reviewed Original ResearchConceptsPostdischarge outcomesTransitions of carePoor patient outcomesInternal medicine residentsPatient outcomesInpatient rotationsMedicine residentsElectronic health record dataTime of dischargeHealth record dataElectronic health recordsDischarge planningFuture practiceFree-text responsesPostintervention surveysHealth recordsRecord dataOutcomesAdditional staffPatientsMedical student participantsReducing Nighttime Interruptions and Improving Sleep for Hospitalized Patients by Restructuring Nighttime Clinical Workflow
Holleck M, Tikkanen K, Holleck J, Frank C, Falco N, Cosentino D, Chang J. Reducing Nighttime Interruptions and Improving Sleep for Hospitalized Patients by Restructuring Nighttime Clinical Workflow. Journal Of General Internal Medicine 2023, 38: 2091-2097. PMID: 36697927, PMCID: PMC10361944, DOI: 10.1007/s11606-022-08005-2.Peer-Reviewed Original ResearchConceptsBlood pressure checkPressure checkHospitalized patientsSleep disruptionClinical workflowNighttime sleep disruptionsVenous thromboembolism prophylaxisGeneral medical wardsPercentage of patientsCross-sectional studyVeterans Administration HospitalWorse sleep qualityKey ResultsAfterNocturnal disruptionsTelemetry patientsThromboembolism prophylaxisMedical wardsImproved sleepMedication administrationAdministration HospitalSleep qualityPatientsNighttime disruptionsSleep surveyHospital