A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes
Carmell M, Dokshin G, Skaletsky H, Hu Y, van Wolfswinkel J, Igarashi K, Bellott D, Nefedov M, Reddien P, Enders G, Uversky V, Mello C, Page D. A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes. ELife 2016, 5: e19993. PMID: 27718356, PMCID: PMC5098910, DOI: 10.7554/elife.19993.Peer-Reviewed Original ResearchConceptsDedicated germlineMajor eukaryotic lineagesDNA damage repairGerm cell markersEukaryotic lineagesDiverse eukaryotesEukaryotic evolutionMulticellular organismsMulticellular animalsSexual reproductionEarly eukaryotesGenomic integrityPhylogenetic analysisAncient familyReproductive cellsDamage repairGene expressionEukaryotesHeritable genomeGerm cellsProteinStem cellsGCNAGermlineCell markers