2023
ISUOG Practice Guidelines (updated): fetal cardiac screening
Carvalho J, Axt‐Fliedner R, Chaoui R, Copel J, Cuneo B, Goff D, Kopylov L, Hecher K, Lee W, Moon‐Grady A, Mousa H, Munoz H, Paladini D, Prefumo F, Quarello E, Rychik J, Tutschek B, Wiechec M, Yagel S. ISUOG Practice Guidelines (updated): fetal cardiac screening. Ultrasound In Obstetrics And Gynecology 2023, 61: 788-803. PMID: 37267096, DOI: 10.1002/uog.26224.Peer-Reviewed Original Research
2022
Impact of prenatally diagnosed congenital heart defects on outcomes and management
Wong J, Kohari K, Bahtiyar MO, Copel J. Impact of prenatally diagnosed congenital heart defects on outcomes and management. Journal Of Clinical Ultrasound 2022, 50: 646-654. PMID: 35543387, DOI: 10.1002/jcu.23219.Peer-Reviewed Original ResearchMeSH KeywordsChildEchocardiographyFemaleFetal HeartHeart Defects, CongenitalHumansInfant, NewbornPregnancyReferral and ConsultationUltrasonography, PrenatalConceptsCongenital heart defectsComplex congenital heart defectEarly fetal echocardiographyImproved survival ratesPrenatal detection rateGood psychosocial supportFetal echocardiogramFetal echocardiographyPatient educationCardiology specialistsHigh riskHeart defectsSurvival rateCongenital heartPsychosocial supportEarly detectionPrenatal identificationPrenatal detectionDelivery planningDetection rateUltrasound technologyImportant contributorEchocardiogramEchocardiographyNeonates
2021
Utility of routine screening fetal echocardiogram in pregnancies conceived by in vitro fertilization
Bjorkman KR, Bjorkman SH, Ferdman DJ, Sfakianaki AK, Copel JA, Bahtiyar MO. Utility of routine screening fetal echocardiogram in pregnancies conceived by in vitro fertilization. Fertility And Sterility 2021, 116: 801-808. PMID: 34210397, DOI: 10.1016/j.fertnstert.2021.04.035.Peer-Reviewed Original ResearchConceptsFetal echocardiogramIncidence of CHDFetal echocardiographyIVF pregnanciesRisk factorsIVF groupInsignificant ventricular septal defectsLarge tertiary care centerStatewide hospital discharge dataMean gestational ageTertiary care centerCases of CHDHospital discharge dataRoutine prenatal careVentricular septal defectConfidence intervalsPopulation ratesBirth Defects RegistrySignificant CHDMedication exposureCohort studyPulmonary stenosisPrevious pregnancyGestational ageInfant outcomesSpecial Report of the Society for Maternal-Fetal Medicine Placenta Accreta Spectrum Ultrasound Marker Task Force: Consensus on definition of markers and approach to the ultrasound examination in pregnancies at risk for placenta accreta spectrum
Shainker SA, Coleman B, Timor I, Bhide A, Bromley B, Cahill AG, Gandhi M, Hecht JL, Johnson KM, Levine D, Mastrobattista J, Philips J, Platt L, Shamshirsaz AA, Shipp TD, Silver RM, Simpson LL, Copel JA, Abuhamad A, Medicine S. Special Report of the Society for Maternal-Fetal Medicine Placenta Accreta Spectrum Ultrasound Marker Task Force: Consensus on definition of markers and approach to the ultrasound examination in pregnancies at risk for placenta accreta spectrum. American Journal Of Obstetrics And Gynecology 2021, 224: b2-b14. PMID: 33386103, DOI: 10.1016/j.ajog.2020.09.001.Peer-Reviewed Original ResearchConceptsPlacenta accreta spectrumUltrasound examinationAmerican CollegePrenatal ultrasound evaluationMaternal-fetal medicineAbnormal placental attachmentTask ForcePlacenta percretaMaternal morbidityPlacenta accretaPlacenta incretaAdherent placentaCesarean deliveryUltrasound evaluationDiagnostic medical sonographySonographic markersUltrasound markersPlacental attachmentExpert consensusInvasive placentationDefinition of markersPrenatal detectionAmerican RegistryUltrasoundPregnancy
2020
Treatment and outcome of 370 cases with spontaneous or post‐laser twin anemia–polycythemia sequence managed in 17 fetal therapy centers
Tollenaar L, Slaghekke F, Lewi L, Ville Y, Lanna M, Weingertner A, Ryan G, Arévalo S, Khalil A, Brock C, Klaritsch P, Hecher K, Gardener G, Bevilacqua E, Kostyukov K, Bahtiyar M, Kilby M, Tiblad E, Oepkes D, Lopriore E, Middeldorp J, Haak M, Klumper F, Akkermans J, Delagrange H, Pandya V, Faiola S, Favre R, Hobson S, Rodo C, Thilaganathan B, Papanna R, Greimel P, de Sousa M, Carlin A, Gladkova K, Copel J. Treatment and outcome of 370 cases with spontaneous or post‐laser twin anemia–polycythemia sequence managed in 17 fetal therapy centers. Ultrasound In Obstetrics And Gynecology 2020, 56: 378-387. PMID: 32291846, PMCID: PMC7497010, DOI: 10.1002/uog.22042.Peer-Reviewed Original ResearchConceptsTwin anemia-polycythemia sequenceFetal therapy centersMonochorionic twin pregnanciesPost-laser twin anemia-polycythemia sequenceExpectant management groupSevere neonatal morbidityIntrauterine transfusionExpectant managementPerinatal mortalitySelective feticideTwin pregnanciesLaser surgeryNeonatal morbidityDelivery groupIUT groupDiagnosis of TAPSMiddle cerebral artery peak systolic velocityFetal middle cerebral artery peak systolic velocityBirth intervalLaser surgery groupProlongation of pregnancyTherapy CenterPeak systolic velocityLarge international cohortMedian diagnosis
2019
Utility of Fetal Cardiac Axis and Cardiac Position Assessment in Predicting Neonatal Respiratory Morbidity in Fetal Congenital Lung Lesions
Tuzovic L, Copel JA, Stitelman DH, Levit O, Bahtiyar MO. Utility of Fetal Cardiac Axis and Cardiac Position Assessment in Predicting Neonatal Respiratory Morbidity in Fetal Congenital Lung Lesions. Journal Of Ultrasound In Medicine 2019, 38: 2361-2372. PMID: 30653685, DOI: 10.1002/jum.14931.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesFemaleFetal HeartHumansLungLung DiseasesPregnancyRetrospective StudiesSensitivity and SpecificityUltrasonography, PrenatalYoung AdultConceptsAbnormal cardiac axisNegative predictive valueFetal cardiac axisNeonatal respiratory morbidityRespiratory morbidityCongenital lung lesionsCardiac positionPositive predictive valuePredictive valueCardiac axisLung lesionsHigh negative predictive valueSevere respiratory morbidityRetrospective cohort studyRight-sided lesionsNormal cardiac axisCohort studyWeeks' gestationMorbidityCP assessmentWeeksDiagnostic performanceLesionsPatientsGestation
2013
ISUOG Practice Guidelines (updated): sonographic screening examination of the fetal heart
International Society of Ultrasound in Obstetrics and Gynecology, Carvalho J, Allan L, Chaoui R, Copel J, DeVore G, Hecher K, Lee W, Munoz H, Paladini D, Tutschek B, Yagel S. ISUOG Practice Guidelines (updated): sonographic screening examination of the fetal heart. Ultrasound In Obstetrics And Gynecology 2013, 41: 348-359. PMID: 23460196, DOI: 10.1002/uog.12403.Commentaries, Editorials and Letters
2012
Comparative Analysis of 2-D Versus 3-D Ultrasound Estimation of the Fetal Adrenal Gland Volume and Prediction of Preterm Birth
Turan O, Turan S, Buhimschi I, Funai E, Campbell K, Bahtiyar O, Harman C, Copel J, Baschat A, Buhimschi C. Comparative Analysis of 2-D Versus 3-D Ultrasound Estimation of the Fetal Adrenal Gland Volume and Prediction of Preterm Birth. American Journal Of Perinatology 2012, 29: 673-680. PMID: 22644825, PMCID: PMC3838705, DOI: 10.1055/s-0032-1314887.Peer-Reviewed Original Research
2011
Assessment of the fetal thymus by two‐ and three‐dimensional ultrasound during normal human gestation and in fetuses with congenital heart defects
Li L, Bahtiyar M, Buhimschi C, Zou L, Zhou Q, Copel J. Assessment of the fetal thymus by two‐ and three‐dimensional ultrasound during normal human gestation and in fetuses with congenital heart defects. Ultrasound In Obstetrics And Gynecology 2011, 37: 404-409. PMID: 20886509, DOI: 10.1002/uog.8853.Peer-Reviewed Original Research
2008
ISUOG consensus statement: what constitutes a fetal echocardiogram?
Lee W, Allan L, Carvalho J, Chaoui R, Copel J, Devore G, Hecher K, Munoz H, Nelson T, Paladini D, Yagel S. ISUOG consensus statement: what constitutes a fetal echocardiogram? Ultrasound In Obstetrics And Gynecology 2008, 32: 239-242. PMID: 18663769, DOI: 10.1002/uog.6115.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConsensusFemaleHeart Defects, CongenitalHumansPractice Guidelines as TopicPregnancyUltrasonography, PrenatalPrenatal Imaging
Reddy UM, Filly RA, Copel JA. Prenatal Imaging. Obstetrics And Gynecology 2008, 112: 145-157. PMID: 18591320, PMCID: PMC2788813, DOI: 10.1097/01.aog.0000318871.95090.d9.Peer-Reviewed Original ResearchMeSH KeywordsFemaleFetal DiseasesHumansImaging, Three-DimensionalMagnetic Resonance ImagingPregnancyPrenatal CareUltrasonography, PrenatalConceptsFetal magnetic resonance imagingMagnetic resonance imagingNervous system anomaliesFetal central nervous system anomaliesEunice Kennedy Shriver National InstituteCentral nervous system anomaliesNon-central nervous system anomaliesSystem anomaliesFirst-trimester ultrasonographyPrediction of prognosisModality of choiceThree-dimensional ultrasonographyAnatomic surveySpecialized centersFetal sedationFetal observationsChild healthPregnancy evaluationPrenatal imagingUltrasonographyResonance imagingAvailable evidenceRemote reviewNational InstituteClinical applicationPrenatal Course of Isolated Muscular Ventricular Septal Defects Diagnosed Only by Color Doppler Sonography
Bahtiyar MO, Dulay AT, Weeks BP, Friedman AH, Copel JA. Prenatal Course of Isolated Muscular Ventricular Septal Defects Diagnosed Only by Color Doppler Sonography. Journal Of Ultrasound In Medicine 2008, 27: 715-720. PMID: 18424646, DOI: 10.7863/jum.2008.27.5.715.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesDown SyndromeEchocardiographyFemaleFetal DevelopmentFetal DiseasesFetal HeartFollow-Up StudiesGestational AgeHeart Septal Defects, VentricularHumansInfant, NewbornNuchal Translucency MeasurementPregnancyPregnancy OutcomeProspective StudiesRisk AssessmentTripletsTwinsUltrasonography, Doppler, ColorUltrasonography, PrenatalConceptsVentricular septal defectColor Doppler examinationMuscular VSDDoppler examinationSeptal defectStudy groupIsolated muscular ventricular septal defectTrisomy 21Isolated ventricular septal defectMuscular ventricular septal defectsHigh-resolution ultrasound equipmentCommon congenital heart defectSmall muscular VSDMean gestational ageFetal echocardiographic examinationColor Doppler sonographyCongenital heart defectsPrenatal resolutionTriplet gestationsEchocardiographic examinationGestational ageCounseling patientsPerinatal courseTwin gestationsFirst trimester
2004
Indications for Fetal Echocardiography
Small M, Copel J. Indications for Fetal Echocardiography. Pediatric Cardiology 2004, 25: 210-222. PMID: 15360114, DOI: 10.1007/s00246-003-0587-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsEchocardiographyFemaleFetal DiseasesFetal HeartHeart Defects, CongenitalHumansPregnancyPregnancy ComplicationsUltrasonography, Prenatal
2002
Midtrimester nuchal thickness and the prediction of postnatal congenital heart defect
Bahado-Singh RO, Rowther M, Bailey J, Copel J, Mendilcioglu I, Choi S, Oz U. Midtrimester nuchal thickness and the prediction of postnatal congenital heart defect. American Journal Of Obstetrics And Gynecology 2002, 187: 1250-1253. PMID: 12439514, DOI: 10.1067/mob.2002.128025.Peer-Reviewed Original ResearchConceptsNuchal thickness measurementPrediction of CHDNuchal thicknessRisk factorsHeart defectsStepwise logistic regression analysisBackground population riskIndividual patient's riskEpidemiologic risk factorsSignificant risk factorsMultiple risk factorsPatient-specific riskSignificant predictorsLogistic regression analysisCongenital heart defectsOnly significant predictorMajor CHDPostnatal evaluationPatient riskMidtrimester fetusesNormal fetusesCongenital heartCHDLogistic regression
2001
Transvaginal sonographic evaluation of fetal anatomy at 14 to 16 weeks. Why it is not feasible in the United States.
Copel J. Transvaginal sonographic evaluation of fetal anatomy at 14 to 16 weeks. Why it is not feasible in the United States. Journal Of Ultrasound In Medicine 2001, 20: 710-711. PMID: 11444728, DOI: 10.7863/jum.2001.20.7.710.Commentaries, Editorials and LettersUltrasound markers of fetal Down syndrome.
Bahado-Singh R, Mendilcioglu I, Copel J. Ultrasound markers of fetal Down syndrome. JAMA 2001, 285: 2857-8. PMID: 11401604.Commentaries, Editorials and LettersIsolated major congenital heart disease
Allan L, Benacerraf B, Copel J, Carvalho J, Chaoui R, Eik-Nes S, Tegnander E, Gembruch U, Huhta J, Pilu G, Wladimiroff J, Yagel S. Isolated major congenital heart disease. Ultrasound In Obstetrics And Gynecology 2001, 17: 370-379. PMID: 11380959, DOI: 10.1046/j.1469-0705.2001.00439.x.Peer-Reviewed Original ResearchRatio of nuchal thickness to humerus length for Down syndrome detection
Bahado-Singh R, Oz U, Hsu C, Deren O, Copel J, Mahoney M. Ratio of nuchal thickness to humerus length for Down syndrome detection. American Journal Of Obstetrics And Gynecology 2001, 184: 1284-1288. PMID: 11349203, DOI: 10.1067/mob.2001.113878.Peer-Reviewed Original ResearchConceptsDown syndrome riskHigh-risk groupMaternal ageSyndrome riskNuchal thicknessDown syndromeDown syndrome detectionStudy populationIndividual Down's syndrome riskMean gestational ageOverall study populationAge-related riskHumerus lengthSyndrome detectionDown syndrome casesDown's syndrome likelihood ratiosGestational ageProspective dataHealthy groupGross anomaliesNormal fetusesSyndrome casesBiparietal diameterAmniocentesis casesFetal populationPrenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient
Verheijen P, Lisowski L, Stoutenbeek P, Hitchcock J, Brenner J, Copel J, Kleinman C, Meijboom E, Bennink G. Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient. Journal Of Thoracic And Cardiovascular Surgery 2001, 121: 798-803. PMID: 11279423, DOI: 10.1067/mtc.2001.112825.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseHeart diseaseLower base excessHeart obstructionMetabolic acidosisBase excessDuctus-dependent congenital heart diseasePrenatal diagnosisPostnatal diagnosisImproved long-term outcomesGroup of patientsArterial blood gasesLong-term outcomesCause of deathHigher lactate levelsDays of lifePrevention of acidosisSignificant differencesBiventricular repairPreoperative conditionCerebral damageRetrospective studySurgical outcomesPreoperative acidosisBlood gases
2000
Color Doppler imaging of placental masses: differential diagnosis and fetal outcome
Prapas N, Liang R, Hunter D, Copel J, Lu L, Pazkash V, Mari G. Color Doppler imaging of placental masses: differential diagnosis and fetal outcome. Ultrasound In Obstetrics And Gynecology 2000, 16: 559-563. PMID: 11169351, DOI: 10.1046/j.1469-0705.2000.00324.x.Peer-Reviewed Original ResearchConceptsCases of chorioangiomaPlacental massPlacental hemorrhagePremature laborDifferential diagnosisRapid tumor growthColor Doppler imagingColor flow mappingPlacental chorioangiomaFetal outcomesPerinatal outcomesNeonatal deathRetrospective studyDoppler examinationBlood flowChorioangiomaColor DopplerDoppler imagingTumor growthHemorrhageHalf year periodFlow mappingOnly caseDiagnosisSuch masses