2024
P116. National trends and risk factors for new-onset depression following posterior lumbar fusion
Day W, Gouzoulis M, Zhu J, Seddio A, Fourman M, Grauer J. P116. National trends and risk factors for new-onset depression following posterior lumbar fusion. The Spine Journal 2024, 24: s119. DOI: 10.1016/j.spinee.2024.06.138.Peer-Reviewed Original ResearchNew-onset depressionPosterior lumbar fusionNational administrative claims databaseSingle-level posterior lumbar fusionRisk factorsDevelopment of new-onset depressionAdministrative claims databasePostoperative complicationsLumbar fusionNational trendsFactors associated with patientsClaims databaseAggregate patient dataAdult patientsTarget risk mitigation strategiesMultivariate logistic regressionPsychiatric risk factorsPotential risk factorsElixhauser Comorbidity IndexPercentage of patientsHigher oddsCase-controlAlcohol/drug abuseDiagnosis of tumorsLogistic regressionRate and risk factors for inpatient falls following single-level posterior lumbar fusion: A national registry study
Gouzoulis M, Jabbouri S, Seddio A, Moran J, Day W, Ratnasamy P, Grauer J. Rate and risk factors for inpatient falls following single-level posterior lumbar fusion: A national registry study. North American Spine Society Journal (NASSJ) 2024, 20: 100549. PMID: 39318705, PMCID: PMC11417567, DOI: 10.1016/j.xnsj.2024.100549.Peer-Reviewed Original ResearchPosterior lumbar fusionSingle-level posterior lumbar fusionInpatient fallsOdds ratioLumbar fusionFall prevention programsIncidence of secondary injuryNational sample of patientsRisk factorsDecreased odds ratioPatient variablesPotential patient outcomesMultivariate logistic regressionNational registry studySample of patientsPrevention programsInpatient costsMedicaid insuranceActive deliriumAlcohol use disorderMethods Adult patientsSpinal pathologyOutcome metricsCommercial insuranceNational sampleRisk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty
Jayaram R, Day W, Gouzoulis M, Zhu J, Grauer J, Rubin L. Risk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty. Arthroplasty Today 2024, 28: 101440. PMID: 39139361, PMCID: PMC11320433, DOI: 10.1016/j.artd.2024.101440.Peer-Reviewed Original ResearchBody mass indexNerve injuryElixhauser Comorbidity IndexRisk factorsMultivariate analysisOdds ratioRisk of nerve injuryTotal hip arthroplastyRevision proceduresObese BMI statusUnderweight body mass indexDecreased odds ratioPatient ageSurgery typeRisk stratificationAdverse eventsBMI statusMass indexFemale sexAdverse outcomesComorbidity indexDecreased riskPatient counselingHip arthroplastyNerveA 10-year perspective on the question of whether surgeries for adolescent idiopathic scoliosis are “one and done”?
Gouzoulis M, Joo P, Jeong S, Jabbouri S, Moran J, Zhu J, Grauer J. A 10-year perspective on the question of whether surgeries for adolescent idiopathic scoliosis are “one and done”? Spine Deformity 2024, 12: 903-908. PMID: 38555557, DOI: 10.1007/s43390-024-00858-3.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisIdiopathic scoliosisRisk factorsAssociated with male sexTime of surgeryLong-term outcomesYear follow-upMultivariate regressionMonths to 2Reoperation incidenceReoperation ratePSF patientsExcellent outcomesPediatric surgeonsReoperationMale sexFollow-upStudy cohortPatient characteristicsPatient counselingSurgeryConclusionsThe current studyInterquartile rangeScoliosis fusionResultsIn total
2023
The Burden of Revision Total Ankle Replacement Has Markedly Increased from 2010 to 2020
Ratnasamy P, Maloy G, Oghenesume O, Peden S, Grauer J, Oh I. The Burden of Revision Total Ankle Replacement Has Markedly Increased from 2010 to 2020. Foot & Ankle Orthopaedics 2023, 8: 2473011423s00199. PMCID: PMC10750518, DOI: 10.1177/2473011423s00199.Peer-Reviewed Original ResearchExplant surgeryRisk factorsYounger ageComorbidity burdenIndependent predictorsFemale sexRevision surgeryMultivariate logistic regression analysisHigher comorbidity burdenPatient comorbidity burdenRevision total ankle replacementTotal ankle replacement surgeryRetrospective cohort studyIndependent risk factorImplant survival rateElixhauser Comorbidity IndexRisk of revisionTiming of revisionLogistic regression analysisSite of careTotal ankle replacementLarge national databaseAnkle replacement surgeryOccurrence of revisionExplant patientsRisk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients
Ratnasamy P, Rudisill K, Oghenesume O, Riedel M, Grauer J. Risk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients. JAAOS Global Research And Reviews 2023, 7: e23.00001. PMID: 37428152, PMCID: PMC10332831, DOI: 10.5435/jaaosglobal-d-23-00001.Peer-Reviewed Original ResearchConceptsContralateral hip fractureInitial hip fractureKaplan-Meier survival analysisGeriatric hip fracturesHip fractureSurvival analysisFragility fracture patientsIndex hip fractureHip fracture fixationKaplan-Meier analysisBody mass indexMultivariate logistic regressionFracture patientsContralateral fractureIndependent predictorsGeriatric patientsHigh morbidityMass indexPatient mortalityFemale sexNational cohortRisk factorsFracture fixationMultivariate analysisLogistic regressionThe Burden of Revision Total Ankle Replacement Has Increased From 2010 to 2020
Ratnasamy P, Maloy G, Oghenesume O, Peden S, Grauer J, Oh I. The Burden of Revision Total Ankle Replacement Has Increased From 2010 to 2020. Foot & Ankle Orthopaedics 2023, 8: 24730114231198234. PMID: 37767009, PMCID: PMC10521287, DOI: 10.1177/24730114231198234.Peer-Reviewed Original ResearchElixhauser Comorbidity IndexHigher Elixhauser comorbidity indexRetrospective cohort studyCohort studyIndependent predictorsAnnual incidenceRevision surgeryRisk factorsYounger ageMultivariate logistic regression analysisRevision total ankle replacementTotal ankle replacement surgeryIndependent risk factorImplant survival rateTiming of revisionLogistic regression analysisSite of careTotal ankle replacementAnkle replacement surgeryExplant patientsExplant surgeryComorbidity indexPatient factorsIndex procedureFemale sexLow Rates of 5-Year Secondary Surgery and Postoperative Complications After Primary Hip Arthroscopy in More Than 30,000 Patients
Gillinov S, Kim D, Moran J, Lee M, Fong S, Mahatme R, Simington J, Owens J, McLaughlin W, Grauer J, Jimenez A. Low Rates of 5-Year Secondary Surgery and Postoperative Complications After Primary Hip Arthroscopy in More Than 30,000 Patients. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2023, 39: 1639-1648. PMID: 37286283, DOI: 10.1016/j.arthro.2023.01.100.Peer-Reviewed Original ResearchConceptsPrimary hip arthroscopySecondary surgery rateMultivariate logistic regressionSecondary surgeryHip arthroscopySurgery ratesRisk factorsFemale sexLabral tearsTenth RevisionHip arthroplastyLabral repairInternational ClassificationClass II/III obesityLogistic regressionPrevious hip arthroscopyClass I obesityPostoperative complication rateRate of complicationsFive-year ratesDay of surgeryFrequent surgical procedureKaplan-Meier analysisTotal hip arthroplastyLarge national datasetEmergency department visits within 90 days of lumbar discectomy
Ratnasamy P, Rudisill K, Caruana D, Kammien A, Grauer J. Emergency department visits within 90 days of lumbar discectomy. The Spine Journal 2023, 23: 1522-1530. PMID: 37356460, DOI: 10.1016/j.spinee.2023.06.384.Peer-Reviewed Original ResearchConceptsElixhauser Comorbidity IndexSurgical site painED visitsED utilizationLumbar discectomySite painUnderwent reoperationPatient factorsPostoperative weekPatient satisfactionPrimary diagnosisRisk factorsCSF leakHealth care resource utilizationHigher Elixhauser comorbidity indexExcess health care expendituresCommon primary diagnosisType of reoperationNerve root decompressionDay of surgeryEmergency department visitsPatient-level predictorsPosterior segmental instrumentationRisk of reoperationSpecific patient characteristics
2022
Postoperative spine surgical site infections: high rate of failure of one-stage irrigation and debridement
Dhodapkar M, Galivanche A, Halperin S, Elaydi A, Rubio D, Grauer J. Postoperative spine surgical site infections: high rate of failure of one-stage irrigation and debridement. The Spine Journal 2022, 23: 484-491. PMID: 36549456, DOI: 10.1016/j.spinee.2022.12.005.Peer-Reviewed Original ResearchConceptsSurgical site infectionElective spine surgerySpine surgeryInitial managementRate of SSIInfection characteristicsSpine surgical site infectionPostoperative surgical site infectionRetrospective case-control studyPresence of bacteremiaRisk stratification toolCase-control studySingle academic institutionTimes greater oddsDevastating complicationSite infectionMultivariable analysisStratification toolSurgical managementSurgical variablesIndex procedureSurgical interventionRisk factorsInclusion criteriaLarge cohortNinety-Day Emergency Department Visits After Ankle Fracture Surgery
Kammien A, Ratnasamy P, Joo P, Grauer J. Ninety-Day Emergency Department Visits After Ankle Fracture Surgery. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 31: e51-e57. PMID: 36548157, DOI: 10.5435/jaaos-d-22-00484.Peer-Reviewed Original ResearchConceptsAnkle fracture surgeryElixhauser comorbidity index scoreComorbidity Index scoreED visitsED utilizationFracture surgeryPostoperative weekRisk factorsSurgical siteIndex scoreIncidence of readmissionEmergency department visitsDay of surgeryMultivariate logistic regressionORIF patientsPatient ageAnkle fracturesDepartment visitsOpen reductionConcomitant fracturesMedicaid insuranceEntire cohortEmergency departmentInternal fixationCare pathwayRisk factors for venous thromboembolism following fractures isolated to the foot and ankle fracture
Gouzoulis MJ, Joo PY, Kammien AJ, McLaughlin WM, Yoo B, Grauer JN. Risk factors for venous thromboembolism following fractures isolated to the foot and ankle fracture. PLOS ONE 2022, 17: e0276548. PMID: 36264985, PMCID: PMC9584400, DOI: 10.1371/journal.pone.0276548.Peer-Reviewed Original ResearchConceptsVenous thromboembolismAnkle fracturesFactor V LeidenSurgical treatmentRisk factorsActive cancerV LeidenTiming of VTEPrior venous thromboembolismIsolated footIndependent risk factorDeep vein thrombosisRisk/benefit considerationsMultivariate logistical regressionSpecific fracture patternsElixhauser indexPulmonary embolismVein thrombosisPearlDiver databaseMetatarsal fracturesAppendicular fracturesMale sexSuch injuriesTraumatic injuryChi-square analysisEmergency Department Visits Within 90 Days of Total Ankle Arthroplasty
Ratnasamy P, Kammien A, Gouzoulis M, Grauer J. Emergency Department Visits Within 90 Days of Total Ankle Arthroplasty. Foot & Ankle Orthopaedics 2022, 7: 2473011421s00895. PMCID: PMC9679845, DOI: 10.1177/2473011421s00895.Peer-Reviewed Original ResearchTotal ankle arthroplastyElixhauser Comorbidity IndexSurgical site painED visitsSite painTAA patientsAnkle arthroplastyRisk factorsCommon reasonHealth care utilization/costsHigher Elixhauser comorbidity indexPostoperative ED visitsRetrospective cohort studyEmergency department visitsDay of surgeryLogistic regression analysisComorbidity indexCohort studyED utilizationDepartment visitsPatient factorsPostoperative weekEmergency departmentPatient populationFemale sexIncidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis
Gillinov SM, Joo PY, Zhu JR, Moran J, Rubin LE, Grauer JN. Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 30: 1047-1053. PMID: 35947825, PMCID: PMC9588560, DOI: 10.5435/jaaos-d-22-00150.Peer-Reviewed Original ResearchConceptsPrimary total hip arthroplastyTotal hip arthroplastyElixhauser Comorbidity IndexBody mass indexComorbidity indexMass indexHip dislocationRevision surgeryRisk factorsHip arthroplastyIndex total hip arthroplastyHigher Elixhauser comorbidity indexPrimary THA patientsFirst-time dislocationCumulative incidenceMost patientsPostoperative dataTHA patientsRecurrent episodesControl subjectsFemale sexLarge cohortPatientsMultivariate analysisYounger ageIncidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients
Gillinov SM, Fosam A, Burroughs PJ, Schneble CA, McLaughlin WM, Moran J, Jimenez AE, Grauer JN, Medvecky MJ. Incidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients. The American Journal Of Sports Medicine 2022, 50: 2893-2899. PMID: 35916771, DOI: 10.1177/03635465221111115.Peer-Reviewed Original ResearchConceptsBony realignment proceduresAutologous chondrocyte implantationBody mass indexPrimary Autologous Chondrocyte ImplantationRevision surgeryRisk factorsRealignment proceduresPostoperative yearKnee arthroplastyFemale sexChondrocyte implantationECI scoresElixhauser comorbidity index scoreChondral defectsComorbidity Index scoreKaplan-Meier analysisLarge national cohortUnicompartmental knee arthroplastyTotal knee arthroplastyOsteochondral allograft transplantationLevel of evidenceOsteochondral autograft transferArticular cartilage proceduresFull-thickness chondral defectsChondral proceduresHidradenitis Suppurativa Leads to Increased Risk of Wound-Related Complications following Total Joint Arthroplasty
Gouzoulis MJ, Kammien AJ, Caruana DL, Wiznia DH, Grauer JN. Hidradenitis Suppurativa Leads to Increased Risk of Wound-Related Complications following Total Joint Arthroplasty. Arthroplasty Today 2022, 16: 169-174. PMID: 35789782, PMCID: PMC9249970, DOI: 10.1016/j.artd.2022.05.013.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyAdverse eventsHS patientsImplant survivalSkin lesionsKaplan-Meier survival curvesNon-HS patientsSurgical site infectionElixhauser Comorbidity IndexInflammatory skin lesionsSpecific adverse eventsLog-rank testPotential risk factorsTotal joint arthroplastyWound-related issuesRisk of woundComorbidity indexAdult patientsSite infectionDegenerative etiologyWound dehiscenceKnee arthroplastyRevision rateRisk factors
2021
Risk Factors for Venous Thromboembolism in Children Undergoing Orthopedic Surgery.
Mets EJ, Pathak N, Galivanche AR, McLynn RP, Frumberg DB, Grauer JN. Risk Factors for Venous Thromboembolism in Children Undergoing Orthopedic Surgery. Orthopedics 2021, 45: 31-37. PMID: 34846239, DOI: 10.3928/01477447-20211124-06.Peer-Reviewed Original ResearchConceptsVenous thromboembolismAdverse eventsRisk factorsOrthopedic surgeryNational Surgical Quality Improvement Program Pediatric databaseSurgeons National Surgical Quality Improvement Program Pediatric databaseIncidence of VTEPostoperative venous thromboembolismMinor adverse eventsPostoperative adverse eventsPreoperative blood transfusionIndependent risk factorMajor adverse eventsHigh-risk subpopulationsVTE prophylaxisPerioperative outcomesPatient demographicsBlood transfusionPatient factorsPediatric patientsSurgical variablesPreventable complicationsFemur fracturesPatient populationRetrospective analysisPredictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture
Haynes MS, Alder KD, Toombs C, Amakiri IC, Rubin LE, Grauer JN. Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture. JAAOS Global Research And Reviews 2021, 5: e20.00221. PMID: 33989253, PMCID: PMC8133215, DOI: 10.5435/jaaosglobal-d-20-00221.Peer-Reviewed Original ResearchConceptsHip fracture populationPostoperative deliriumPreoperative dementiaHip fractureGeriatric hip fracture populationDependent functional statusFracture populationAdverse postoperative outcomesHigher American SocietyIndependent risk factorPostoperative adverse outcomesGeriatric patient populationNongeneral anesthesiaPreoperative diabetesPostoperative outcomesIndependent predictorsMale sexAdverse outcomesPatient populationFunctional statusRevision surgeryRisk factorsDeliriumHigher oddsRisk subpopulations
2020
Incidence, predictors, and timing of post-operative stroke following elective total hip arthroplasty and total knee arthroplasty
Haynes MS, Alder KD, Bellamkonda K, Kuzomunhu L, Grauer JN. Incidence, predictors, and timing of post-operative stroke following elective total hip arthroplasty and total knee arthroplasty. PLOS ONE 2020, 15: e0239239. PMID: 32941539, PMCID: PMC7498016, DOI: 10.1371/journal.pone.0239239.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyTotal hip arthroplastyIndependent risk factorPostoperative day twoPostoperative strokeKnee arthroplastyRisk factorsHip arthroplastyElective primary total hip arthroplastyTHA/TKANational Surgical Quality Improvement databaseElective total hip arthroplastyDay twoPrimary total hip arthroplastyPost-operative strokePostoperative day nineTiming of strokeHigher American SocietyIncidence of strokePostoperative day oneMajority of strokesQuality improvement databaseRetrospective comparative studyAnesthesiologists (ASA) scoreCouncil patientsReadmissions After Distal Radius Fracture Open Reduction and Internal Fixation: An Analysis of 11,124 Patients
Malpani R, John TS, Mercier MR, Ottesen TD, Nduaguba AM, Webb ML, Grauer JN. Readmissions After Distal Radius Fracture Open Reduction and Internal Fixation: An Analysis of 11,124 Patients. JAAOS Global Research And Reviews 2020, 4: e20.00110. PMID: 33969951, PMCID: PMC7384800, DOI: 10.5435/jaaosglobal-d-20-00110.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseImprovement Program databaseMultivariate analysisAnesthesiologists classOpen reductionInternal fixationRisk factorsProgram databaseMedical reasonsSurgeons National Surgical Quality Improvement Program databasePredictors of readmissionInsulin-dependent diabetesCommon surgical procedureQuality improvement initiativesAmerican SocietyPostoperative readmissionsIndex surgeryInsulin usePerioperative factorsUnplanned readmissionPatient demographicsPerioperative outcomesAdult patientsSurgical reasons