2023
Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis
Moledina D, Obeid W, Smith R, Rosales I, Sise M, Moeckel G, Kashgarian M, Kuperman M, Campbell K, Lefferts S, Meliambro K, Bitzer M, Perazella M, Luciano R, Pober J, Cantley L, Colvin R, Wilson F, Parikh C. Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis. Journal Of Clinical Investigation 2023, 133: e168950. PMID: 37395276, PMCID: PMC10313360, DOI: 10.1172/jci168950.Peer-Reviewed Original ResearchConceptsUrinary CXCL9External validation cohortValidation cohortControl groupAIN diagnosisDiscovery cohortKidney tissueDiagnostic biomarkersAcute interstitial nephritisCXCL9 mRNA expressionAcute kidney injuryBiopsy-confirmed diagnosisAvailable clinical testsNational InstituteKidney injuryTubulointerstitial nephritisInterstitial nephritisKidney biopsyHistological confirmationHistological diagnosisTreatment optionsLymphocyte chemotaxisCXCL9MRNA expression differencesPatients
2005
Second Prize: Simple Method for Achieving Renal Parenchymal Hypothermia for Pure Laparoscopic Partial Nephrectomy
Webster TM, Moeckel GW, Herrell SD. Second Prize: Simple Method for Achieving Renal Parenchymal Hypothermia for Pure Laparoscopic Partial Nephrectomy. Journal Of Endourology 2005, 19: 1075-1081. PMID: 16283843, DOI: 10.1089/end.2005.19.1075.Peer-Reviewed Original ResearchConceptsPure laparoscopic partial nephrectomyLaparoscopic partial nephrectomyCore body temperaturePartial nephrectomyRenal vein bloodRenal vascular occlusionPhase 3Body temperaturePhase 1 testingPhase 2Renal parenchymaPathologic analysisHuman trialsProtective effectControl groupSurvival surgeryCreatinine resultsDegrees CNephrectomyReperfusionCreatinine assaysAverage timeSurgeryHypothermiaPhase 1