2023
Pediatric HIV Disclosure Intervention Improves Immunologic Outcome at 48 Weeks: The Sankofa Trial Experience
Shabanova V, Emuren L, Gan G, Antwi S, Renner L, Amissah K, Kusah J, Lartey M, Reynolds N, Paintsil E. Pediatric HIV Disclosure Intervention Improves Immunologic Outcome at 48 Weeks: The Sankofa Trial Experience. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 94: 371-380. PMID: 37643414, PMCID: PMC10617661, DOI: 10.1097/qai.0000000000003292.Peer-Reviewed Original ResearchConceptsHIV disclosure interventionsVirologic outcomesCD4 percentWeek 48HIV statusIntervention groupHIV disclosureDisclosure interventionDetectable viral loadWorld Health OrganizationAntiretroviral therapyImmunologic outcomesClinical outcomesIntervention armViral loadControl armClinical trialsTrial experienceSecondary analysisDisclosure statusHealth OrganizationCategorical variablesWeeksLinear mixed modelsBaseline
2020
Clinic-Based Pediatric Disclosure Intervention Trial Improves Pediatric HIV Status Disclosure in Ghana.
Paintsil E, Kyriakides TC, Antwi S, Renner L, Nichols JS, Amissah K, Kusah JT, Alhassan A, Ofori IP, Catlin AC, Gan G, Lartey M, Reynolds NR. Clinic-Based Pediatric Disclosure Intervention Trial Improves Pediatric HIV Status Disclosure in Ghana. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 84: 122-131. PMID: 32049772, PMCID: PMC7138721, DOI: 10.1097/qai.0000000000002316.Peer-Reviewed Original ResearchConceptsTreatment groupsHIV disclosure interventionsHIV health careHIV-positive childrenMultivariate Cox modelDisclosure interventionHIV status disclosureBetter overall treatment effectHealth care providersYears of ageChild-caregiver dyadsOverall treatment effectModified intentionHIV clinicHIV statusIntervention armIntervention trialsStatus disclosureTreat approachCare providersCox modelTime pointsTherapeutic communicationControl participantsHealth care
2019
HLA, Non-HLA Antibodies, and Eplet Mismatches in Pediatric Liver Transplantation: Observations From a Small, Single-Center Cohort.
Ekong UD, Antala S, Bow L, Sese D, Morotti R, Rodriguez-Davalos M, Gan G, Deng Y, Emre SH. HLA, Non-HLA Antibodies, and Eplet Mismatches in Pediatric Liver Transplantation: Observations From a Small, Single-Center Cohort. Experimental And Clinical Transplantation 2019, 17: 6-17. PMID: 30777518, PMCID: PMC11165937, DOI: 10.6002/ect.mesot2018.l30.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsChildChild, PreschoolConnecticutFemaleGraft RejectionGraft SurvivalHistocompatibilityHistocompatibility TestingHLA AntigensHumansImmunosuppressive AgentsInfantIsoantibodiesLiver TransplantationMaleRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeYoung AdultConceptsDonor-specific antibodiesEpitope mismatchesMismatch loadAcute rejectionClass II donor-specific antibodiesDQ lociDQ Donor-Specific AntibodiesNon-HLA antibodiesAntibody-mediated rejectionPediatric liver transplantationSingle-center cohortHLAMatchmaker softwareImmunosuppression strategiesLiver transplantLiver transplantationAllograft fibrosisEplet mismatchesLiver biopsyPediatric patientsFibrosis scoreHLA-DRRetrospective reviewTransplant physiciansHLA-DQHLA-DQB1
2018
High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana
Nichols JS, Kyriakides TC, Antwi S, Renner L, Lartey M, Seaneke OA, Obeng R, Catlin AC, Gan G, Reynolds NR, Paintsil E, Team O. High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana. AIDS Care 2018, 31: 25-34. PMID: 30235940, PMCID: PMC6288009, DOI: 10.1080/09540121.2018.1524113.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyART adherence ratesPediatric HIV carePrevalence of adherenceAntiretroviral medication adherenceCohort of childrenHIV-positive statusChildren of caregiversChild-caregiver dyadsHIV carePharmacy recordsRefill dataMedian adherenceMedication adherenceAdherence ratesPoor adherenceHigh prevalencePositive statusIntervention studiesHIVGood adherenceAdherenceBaseline dataChildrenTherapy