A personalized medicine approach to ovulation induction/ovarian stimulation: development of a predictive model and online calculator from level-I evidence
Souter I, Sun F, Zhang H, Diamond MP, Legro RS, Wild RA, Hansen KR, Santoro N, Network F. A personalized medicine approach to ovulation induction/ovarian stimulation: development of a predictive model and online calculator from level-I evidence. Fertility And Sterility 2022, 117: 408-418. PMID: 35125179, PMCID: PMC8985501, DOI: 10.1016/j.fertnstert.2021.10.024.Peer-Reviewed Original ResearchMeSH KeywordsAdultBody Mass IndexClinical Decision-MakingCoitusDecision Support TechniquesFemaleFertilityFertility Agents, FemaleHumansInfertility, FemaleInsemination, ArtificialMaleMaternal AgeOvulation InductionPolycystic Ovary SyndromePrecision MedicinePregnancyPregnancy RateRandomized Controlled Trials as TopicRisk AssessmentRisk FactorsTreatment OutcomeConceptsCumulative pregnancy rateAntimüllerian hormone levelsBody mass indexMultiple pregnanciesPregnancy rateClinical pregnancyOvulation inductionOvarian responseMedication doseMass indexHormone levelsLower body mass indexPregnancy rate/cyclePartner ageHigh antral follicle countLower medication doseMultiple Intrauterine GestationsMultiple pregnancy rateAntral follicle countPolycystic ovary syndromeCharacteristic curveMultivariable regression modelsPersonalized medicine approachGonadotropin useIndividualized chance