2024
Race, Ethnicity, and Gender Differences in Patient Reported Well-Being and Cognitive Functioning Within 3 Months of Symptomatic Illness During COVID-19 Pandemic
Hill M, Huebinger R, Ebna Mannan I, Yu H, Wisk L, O’Laughlin K, Gentile N, Stephens K, Gottlieb M, Weinstein R, Koo K, Santangelo M, Saydah S, Spatz E, Lin Z, Schaeffer K, Kean E, Montoy J, Rodriguez R, Idris A, McDonald S, Elmore J, Venkatesh A. Race, Ethnicity, and Gender Differences in Patient Reported Well-Being and Cognitive Functioning Within 3 Months of Symptomatic Illness During COVID-19 Pandemic. Journal Of Racial And Ethnic Health Disparities 2024, 1-18. PMID: 39172356, DOI: 10.1007/s40615-024-02124-8.Peer-Reviewed Original ResearchPROMIS T-scoresPain interferenceBlack participantsWell-beingHealth-related quality of lifeNon-Hispanic white participantsCognitive functionMeasures of healthHealth-related qualityMethodsThis prospective cohort studyFollow-up surveyProspective cohort studyT-scoreQuality of lifeCOVID-19-related health outcomesLower well-beingPROMIS-29Physical functionHealth outcomesBaseline to 3Social participationWhite participantsCohort studyCOVID-19Sleep disturbanceEvaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA)
Maayah M, Latif N, Vijay A, Gallegos C, Cigarroa N, Martinez E, Mazure C, Miller E, Spatz E, Shah S. Evaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA). Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 3: 102195. PMID: 39166160, PMCID: PMC11330936, DOI: 10.1016/j.jscai.2024.102195.Peer-Reviewed Original ResearchIschemic heart diseaseNonobstructive coronary arteriesCoronary artery diseaseArtery diseaseObstructive coronary artery diseaseCoronary arteryLong-term cardiovascular prognosisHeart diseaseSuspected ischemic heart diseaseAtherosclerotic coronary artery diseaseCoronary vasomotor disordersPretest probability of diseasePragmatic diagnostic algorithmExpert consensus documentEvaluating ischemic heart diseaseImpact quality of lifeQuality of lifeSymptomatic patientsPretest probabilityANOCACardiovascular prognosisVasomotor disordersDiagnostic evaluationPersistent symptomsDiagnostic strategies
2023
Illness Perception and the Impact of a Definitive Diagnosis on Women With Ischemia and No Obstructive Coronary Artery Disease: A Qualitative Study.
Tseng L, Göç N, Schwann A, Cherlin E, Kunnirickal S, Odanovic N, Curry L, Shah S, Spatz E. Illness Perception and the Impact of a Definitive Diagnosis on Women With Ischemia and No Obstructive Coronary Artery Disease: A Qualitative Study. Circulation Cardiovascular Quality And Outcomes 2023, 16: 521-529. PMID: 37476997, DOI: 10.1161/circoutcomes.122.009834.Peer-Reviewed Original ResearchConceptsObstructive coronary artery diseaseCoronary function testingCoronary artery diseaseInvasive coronary angiographyArtery diseaseCoronary angiographyFunction testingDefinitive diagnosisYale-New Haven HospitalNon-Hispanic blacksMore patient-centered careNew Haven HospitalPatient-centered careStructured telephone interviewQuality of lifeHealth care experiencesNon-Hispanic whitesGroup of womenCoronary functionIllness perceptionsMean ageINOCAUncertain causeMultidisciplinary teamPatient care
2019
Associations between community well-being and hospitalisation rates: results from a cross-sectional study within six US states
Roy B, Riley C, Herrin J, Spatz E, Hamar B, Kell KP, Rula EY, Krumholz H. Associations between community well-being and hospitalisation rates: results from a cross-sectional study within six US states. BMJ Open 2019, 9: e030017. PMID: 31780588, PMCID: PMC6886944, DOI: 10.1136/bmjopen-2019-030017.Peer-Reviewed Original ResearchConceptsHospitalisation ratesZip codesPrimary care physician densityCross-sectional study SETTINGCancer-related admissionsRespiratory-related admissionsCross-sectional studyQuality of lifeRace/ethnicityCause hospitalisationSecondary outcomesPrimary outcomeHighest quintileUnnecessary hospitalisationAdmission ratesSD increaseHospitalisationLife benefitsPhysician densityStudy settingMain independent variableBeing IndexHospital bedsAdmissionGallup-Sharecare WellAssociation of Diabetes Mellitus With Health Status Outcomes in Young Women and Men After Acute Myocardial Infarction: Results From the VIRGO Study
Ding Q, Funk M, Spatz ES, Whittemore R, Lin H, Lipska KJ, Dreyer RP, Spertus JA, Krumholz HM. Association of Diabetes Mellitus With Health Status Outcomes in Young Women and Men After Acute Myocardial Infarction: Results From the VIRGO Study. Journal Of The American Heart Association 2019, 8: e010988. PMID: 31441351, PMCID: PMC6755841, DOI: 10.1161/jaha.118.010988.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsDiabetes MellitusFemaleHealth StatusHealth Status IndicatorsHumansMaleMental HealthMiddle AgedMyocardial InfarctionPatient Reported Outcome MeasuresPredictive Value of TestsPrevalencePrognosisQuality of LifeRecovery of FunctionRisk AssessmentRisk FactorsSex FactorsSpainTime FactorsUnited StatesYoung AdultConceptsAcute myocardial infarctionEuroQol visual analogue scaleSeattle Angina QuestionnaireDiabetes mellitusForm Health SurveyHealth status outcomesHealth statusVIRGO StudyAnalog scaleMyocardial infarctionHealth SurveyStatus outcomesYoung adultsSAQ angina frequencyCardiovascular risk factorsHealth status scoresRisk of mortalityWorse health statusPoor health statusQuality of lifeWorse anginaAngina QuestionnaireClinical characteristicsHealthcare useStatus score
2018
Association Between Financial Burden, Quality of Life, and Mental Health Among Those With Atherosclerotic Cardiovascular Disease in the United States
Annapureddy A, Valero-Elizondo J, Khera R, Grandhi GR, Spatz ES, Dreyer RP, Desai NR, Krumholz HM, Nasir K. Association Between Financial Burden, Quality of Life, and Mental Health Among Those With Atherosclerotic Cardiovascular Disease in the United States. Circulation Cardiovascular Quality And Outcomes 2018, 11: e005180. PMID: 30571331, DOI: 10.1161/circoutcomes.118.005180.Peer-Reviewed Original ResearchIdentifying county characteristics associated with resident well-being: A population based study
Roy B, Riley C, Herrin J, Spatz ES, Arora A, Kell KP, Welsh J, Rula EY, Krumholz HM. Identifying county characteristics associated with resident well-being: A population based study. PLOS ONE 2018, 13: e0196720. PMID: 29791476, PMCID: PMC5965855, DOI: 10.1371/journal.pone.0196720.Peer-Reviewed Original ResearchConceptsCounty-level factorsClinical careCross-sectional studyQuality of lifeBetter health outcomesMulti-dimensional assessmentHealth outcomesBeing IndexGallup-Sharecare WellUS residentsCareCounty characteristicsSurvey participantsResident wellUS countiesScoresCounty equivalentsAssessmentFactorsCohort
2016
Economic Impact of Moderate‐Vigorous Physical Activity Among Those With and Without Established Cardiovascular Disease: 2012 Medical Expenditure Panel Survey
Valero‐Elizondo J, Salami JA, Osondu CU, Ogunmoroti O, Arrieta A, Spatz ES, Younus A, Rana JS, Virani SS, Blankstein R, Blaha MJ, Veledar E, Nasir K. Economic Impact of Moderate‐Vigorous Physical Activity Among Those With and Without Established Cardiovascular Disease: 2012 Medical Expenditure Panel Survey. Journal Of The American Heart Association 2016, 5: e003614. PMID: 27604455, PMCID: PMC5079024, DOI: 10.1161/jaha.116.003614.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedArrhythmias, CardiacCardiovascular DiseasesCase-Control StudiesCoronary Artery DiseaseDiabetes MellitusExerciseFemaleHealth ExpendituresHealth ServicesHeart FailureHumansHypercholesterolemiaHypertensionMaleMiddle AgedObesityPeripheral Arterial DiseaseRetrospective StudiesSmokingStrokeUnited StatesYoung AdultConceptsModerate-vigorous physical activityDays/weekPhysical activityHealth care expendituresTotal annual health care expendituresLower health care expendituresAnnual health care expendituresCare expendituresLower health care spendingModifiable risk factorsCardiovascular disease outcomesMedical Expenditure Panel SurveyFinal study sampleYears of ageQuality of lifeMedical Expenditure PanelLink logCVD statusHealth care spendingRisk factorsDisease outcomeStudy populationUS adultsRepresentative cohortTwo-part econometric model
2015
Sex Differences in Perceived Stress and Early Recovery in Young and Middle-Aged Patients With Acute Myocardial Infarction
Xu X, Bao H, Strait K, Spertus JA, Lichtman JH, D'Onofrio G, Spatz E, Bucholz EM, Geda M, Lorenze NP, Bueno H, Beltrame JF, Krumholz HM. Sex Differences in Perceived Stress and Early Recovery in Young and Middle-Aged Patients With Acute Myocardial Infarction. Circulation 2015, 131: 614-623. PMID: 25679303, PMCID: PMC4652932, DOI: 10.1161/circulationaha.114.012826.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMiddle-aged patientsMyocardial infarctionMental health statusWorse recoveryHealth statusSex differencesBaseline stressSex-based disparitiesYears of ageMultiple health outcomesQuality of lifeGreater mental stressSex-based differencesClinical characteristicsFemale sexEarly recoveryPerceived Stress ScaleGeneral populationGreater psychological stressHealth outcomesImprovement scoresInfarctionPatientsYounger age
2014
Effect of Low Perceived Social Support on Health Outcomes in Young Patients With Acute Myocardial Infarction: Results From the Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients (VIRGO) Study
Bucholz EM, Strait KM, Dreyer RP, Geda M, Spatz ES, Bueno H, Lichtman JH, D'Onofrio G, Spertus JA, Krumholz HM. Effect of Low Perceived Social Support on Health Outcomes in Young Patients With Acute Myocardial Infarction: Results From the Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients (VIRGO) Study. Journal Of The American Heart Association 2014, 3: e001252. PMID: 25271209, PMCID: PMC4323798, DOI: 10.1161/jaha.114.001252.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYoung AMI Patients (VIRGO) studyLow social supportQuality of lifeDepressive symptomsHealth statusYounger patientsMyocardial infarctionHealth outcomesENRICHD Social Support InventoryLow Perceived Social SupportSocial supportDepressive symptoms 12 monthsBaseline health statusLower functional statusWorse physical functioningWorse health statusPatient studiesSymptoms 12 monthsLower mental functioningMore depressive symptomsMultivariable adjustmentSocial Support InventoryAMI patientsFunctional status