2019
Movement and Performance Explain Widespread Cortical Activity in a Visual Detection Task
Salkoff D, Zagha E, McCarthy E, McCormick D. Movement and Performance Explain Widespread Cortical Activity in a Visual Detection Task. Cerebral Cortex 2019, 30: 421-437. PMID: 31711133, PMCID: PMC7029483, DOI: 10.1093/cercor/bhz206.Peer-Reviewed Original ResearchConceptsVisual detection taskSecondary motor cortexTask performanceTask-related movementsCortical activityMotor cortexDetection taskTask-independent processesOptimal task performanceWidespread cortical activityTask-related changesHead-fixed miceResponse choicesDorsal cortexOrofacial movementsNeural activityTrial variationLick responsesArousal stateTrial variabilityTarget trialsLick rateCortexCortical signalsTrials
2015
Competing Neural Ensembles in Motor Cortex Gate Goal-Directed Motor Output
Zagha E, Ge X, McCormick DA. Competing Neural Ensembles in Motor Cortex Gate Goal-Directed Motor Output. Neuron 2015, 88: 565-577. PMID: 26593093, PMCID: PMC4660255, DOI: 10.1016/j.neuron.2015.09.044.Peer-Reviewed Original ResearchConceptsPopulations of neuronsAnticipation of movementMotor cortexCortical neuronsCortical circuitsIntracellular techniquesUnit recordingsNeural ensemblesMotor outputNeuronsSensory stimuliNeural activityMotor representationsSensory detection taskMotor commandsFuture studiesTask-related neural dynamicsCortexMiceCellular activities