Featured Publications
Declines in Pneumonia Mortality Following the Introduction of Pneumococcal Conjugate Vaccines in Latin American and Caribbean Countries
de Oliveira LH, Shioda K, Valenzuela M, Janusz CB, Rearte A, Sbarra AN, Warren JL, Toscano CM, Weinberger DM, Team M. Declines in Pneumonia Mortality Following the Introduction of Pneumococcal Conjugate Vaccines in Latin American and Caribbean Countries. Clinical Infectious Diseases 2020, 73: 306-313. PMID: 32448889, PMCID: PMC8516507, DOI: 10.1093/cid/ciaa614.Peer-Reviewed Original ResearchConceptsPneumonia mortalityPneumonia deathsAge groupsIntroduction of PCVPneumococcal conjugate vaccinePediatric immunization programsYears of ageCause pneumoniaMulticountry evaluationPCV introductionConjugate vaccinePostvaccination periodImmunization programsChildren 2Age strataPopulation-level impactMortalityPneumoniaMortality dataStandardized protocolModerate incidenceDeathNational-level mortality dataVaccinePCV
2023
2618. Four Respiratory Viruses are Involved in the Majority of Community-Acquired Alveolar Pneumonia (CAAP) Episodes in Children < 5 Years
Dagan R, van der Beek B, Greenberg D, Ben-Shimol S, Keren-Naos A, Weinberger D, Danino D. 2618. Four Respiratory Viruses are Involved in the Majority of Community-Acquired Alveolar Pneumonia (CAAP) Episodes in Children < 5 Years. Open Forum Infectious Diseases 2023, 10: ofad500.2231. PMCID: PMC10679033, DOI: 10.1093/ofid/ofad500.2231.Peer-Reviewed Original ResearchAlveolar pneumoniaRespiratory virusesBacterial-viral coinfectionsOnly medical centerProspective active surveillanceYoung childrenGrant/research supportParainfluenza virusActive surveillanceMedical CenterNasal samplesHospitalizationPositive specimensEpidemiological activityViral detectionStudy periodViral activityMonthly incidenceMultiple studiesVirusPneumoniaChildrenEpisodesMain virusesRSV
2010
Association of Serotype with Risk of Death Due to Pneumococcal Pneumonia: A Meta-Analysis
Weinberger DM, Harboe ZB, Sanders EA, Ndiritu M, Klugman KP, Rückinger S, Dagan R, Adegbola R, Cutts F, Johnson HL, O'Brien KL, Scott JA, Lipsitch M. Association of Serotype with Risk of Death Due to Pneumococcal Pneumonia: A Meta-Analysis. Clinical Infectious Diseases 2010, 51: 692-699. PMID: 20715907, PMCID: PMC2927802, DOI: 10.1086/655828.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseaseRisk of deathCarriage prevalenceHost factorsAssociation of serotypesLower comorbidity scorePooled effect estimatesStudy-specific estimatesNasopharyngeal carriage prevalenceCase fatality ratioSerotype-specific dataHigher carriage prevalenceRandom-effects methodBacteremic pneumoniaPooled RRComorbidity scorePneumococcal pneumoniaPneumococcal diseaseMeningitis patientsDisease outcomePotential confoundingPneumoniaSerotype 14Epidemiologic measuresMeta-Analysis