2022
Robust prediction of memory and neuroticism in men and women using connectome‐based predictive modeling
Ju S, Horien C, Constable T, Fredericks C. Robust prediction of memory and neuroticism in men and women using connectome‐based predictive modeling. Alzheimer's & Dementia 2022, 18 DOI: 10.1002/alz.063015.Peer-Reviewed Original ResearchConnectome-based predictive modelingAlzheimer's diseaseRAVLT measuresFunctional MRI scansBackground Alzheimer's diseaseHealthy womenNeurobehavioral scoresHealthy subjectsHigh riskMemory performanceMRI scansBrain circuitryBrain connectivityWomenMenSexBrain connectomeDiseasePearson correlationScoresPredictorsConnectivity matrixBrain-based predictorsBehavioral measuresSubjectsPhenotypic Heterogeneity among GBA p.R202X Carriers in Lewy Body Spectrum Disorders
Napolioni V, Fredericks CA, Kim Y, Channappa D, Khan RR, Kim LH, Zafar F, Couthouis J, Davidzon GA, Mormino EC, Gitler AD, Montine TJ, Schüle B, Greicius MD. Phenotypic Heterogeneity among GBA p.R202X Carriers in Lewy Body Spectrum Disorders. Biomedicines 2022, 10: 160. PMID: 35052839, PMCID: PMC8774039, DOI: 10.3390/biomedicines10010160.Peer-Reviewed Original ResearchLewy body spectrum disordersParkinson's diseaseDisease patientsPathogenic roleGlucocerebrosidase 1 (GBA1) geneLewy body dementiaEarly disease onsetSystematic literature searchGaucher disease patientsPhenotypic heterogeneityNeuropathologic evaluationNeuropathologic featuresPathological featuresDisease onsetClinical penetranceSpectrum disorderGBA p.Index caseGaucher diseaseLiterature searchUnaffected relativesPatientsDiseaseNonsense variantAffected subjects
2019
P4‐576: CONCORDANCE BETWEEN 18F‐PI‐2620 TAU PET/MRI IMAGING AND CLINICAL OUTCOMES IN ALZHEIMER DISEASE AND OTHER TAUOPATHIES
Koran M, Davidzon G, Azevedo C, Toueg T, Nadiadwala A, Castillo J, Hall J, Sha S, Fredericks C, Greicius M, Wagner A, Zaharchuk G, Chin F, Mormino E. P4‐576: CONCORDANCE BETWEEN 18F‐PI‐2620 TAU PET/MRI IMAGING AND CLINICAL OUTCOMES IN ALZHEIMER DISEASE AND OTHER TAUOPATHIES. Alzheimer's & Dementia 2019, 15: p1541-p1541. DOI: 10.1016/j.jalz.2019.08.124.Peer-Reviewed Original ResearchRelative preservation of facial expression recognition in posterior cortical atrophy.
Pressman PS, Gola K, Shdo SM, Miller BL, Fredericks C, Mielke C, Pelak V, Rankin KP. Relative preservation of facial expression recognition in posterior cortical atrophy. Neurology 2019, 92: e1064-e1071. PMID: 30760634, PMCID: PMC6442010, DOI: 10.1212/wnl.0000000000007075.Peer-Reviewed Original ResearchConceptsPosterior cortical atrophyBehavioral variant frontotemporal dementiaAlzheimer's diseaseCortical atrophyHealthy controlsVariant frontotemporal dementiaObservational studyRelative preservationAffective blindsightBvFTD groupFrontotemporal dementiaPatientsGroup differencesAtrophyGroupDementiaDisease