2020
Evolution of Embryo Implantation Was Enabled by the Origin of Decidual Stromal Cells in Eutherian Mammals
Chavan AR, Griffith OW, Stadtmauer D, Maziarz J, Pavlicev M, Fishman R, Koren L, Romero R, Wagner GP. Evolution of Embryo Implantation Was Enabled by the Origin of Decidual Stromal Cells in Eutherian Mammals. Molecular Biology And Evolution 2020, 38: 1060-1074. PMID: 33185661, PMCID: PMC7947829, DOI: 10.1093/molbev/msaa274.Peer-Reviewed Original ResearchConceptsEutherian mammalsEutherian lineagesDecidual stromal cellsNovel cell typesStromal cellsInflammatory responseStem lineageEutherian pregnancyCommon ancestorEvolutionary mechanismsExtended gestationMost marsupialsEmbryo attachmentEmbryo implantationMarsupialsLineagesCell typesMammalsMechanistic understandingEutheriansHelper T cellsFetal-maternal interfaceMammalian pregnancyMaternal tissuesNeutrophil recruitment
2019
Endometrial recognition of pregnancy occurs in the grey short-tailed opossum ( Monodelphis domestica).
Griffith OW, Chavan AR, Pavlicev M, Protopapas S, Callahan R, Maziarz J, Wagner GP. Endometrial recognition of pregnancy occurs in the grey short-tailed opossum ( Monodelphis domestica). Proceedings Of The Royal Society B 2019, 286: 20190691. PMID: 31213185, PMCID: PMC6599997, DOI: 10.1098/rspb.2019.0691.Peer-Reviewed Original ResearchConceptsRecognition of pregnancyGene expression changesProtein level differencesUpregulation of genesOestrous cycleStem lineagePlesiomorphic modeTranscriptional landscapeEutherian mammalsTranscriptional differencesUterus of femalesAmerican marsupialsMost marsupialsExpression changesFetal supportMarsupialsSteroid hormone profilesOpossumGenesEmbryosHuman pregnancyTransporter abundanceHormone profilesMaternal physiologyPregnancy