2024
An update on the global disparities in kidney disease burden and care across world countries and regions
Bello A, Okpechi I, Levin A, Ye F, Damster S, Arruebo S, Donner J, Caskey F, Cho Y, Davids M, Davison S, Htay H, Jha V, Lalji R, Malik C, Nangaku M, See E, Sozio S, Tonelli M, Wainstein M, Yeung E, Johnson D, Group I, Abu-Alfa A, Amouzegar A, Anand S, Arogundade F, Ashuntantang G, Bavanandan S, Coppo R, Diongole H, Divyaveer S, Ekrikpo U, Ethier I, Fung W, Gaipov A, Ghimire A, Houston G, Ibrahim K, Irish G, Jindal K, Kelly D, Lightstone L, Madero M, Nalado A, Neuen B, Olanrewaju T, Osman M, Parekh R, Petrova A, Prasad N, Prikhodina L, Racki S, Riaz P, Saad S, Sakajiki A, Savaj S, Shah D, Suzuki Y, Tesar V, Tiv S, Tungsanga S, Tzanno-Martins C, Viecelli A, Wang A, Wong M, Zaidi D. An update on the global disparities in kidney disease burden and care across world countries and regions. The Lancet Global Health 2024, 12: e382-e395. PMID: 38365413, DOI: 10.1016/s2214-109x(23)00570-3.Peer-Reviewed Original ResearchMeSH KeywordsChildCost of IllnessDelivery of Health CareHumansKidneyRenal DialysisRenal Insufficiency, ChronicConceptsConservative kidney managementLow-resource settingsCountry income levelKidney replacement therapyKidney careHealth workforce shortagesWHO building blocksLiterature review of published reportsGlobal Kidney Health AtlasWorld Bank income groupsKidney care deliveryBurden of chronic kidney diseaseBurden of kidney diseaseGlobal burden of kidney diseaseAnnual median costsChronic kidney diseaseHigh-income countriesKidney disease burdenPhases of data collectionPrevalence of chronic kidney diseaseIncome levelPoint of deliveryAffordability of medicinesCare deliveryWorkforce shortages
2021
Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference
Babitt J, Eisenga M, Haase V, Kshirsagar A, Levin A, Locatelli F, Małyszko J, Swinkels D, Tarng D, Cheung M, Jadoul M, Winkelmayer W, Drüeke T, Participants C, Abu-Alfa A, Afsar B, Pai A, Besarab A, Moore G, Casadevall N, Cases A, de Francisco A, Eckardt K, Fishbane S, Fried L, Ganz T, Ginzburg Y, Gómez R, Goodnough L, Hamano T, Hanudel M, Hao C, Iseki K, Ix J, Johansen K, Ketteler M, Kovesdy C, Leaf D, Macdougall I, Massy Z, McMahon L, Minutolo R, Nakanishi T, Nemeth E, Obrador G, Parfrey P, Park H, Pecoits-Filho R, Robinson B, Roger S, Shah Y, Spinowitz B, Tanaka T, Tsukamoto Y, Tungsanga K, Walther C, Wang A, Wolf M. Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference. Kidney International 2021, 99: 1280-1295. PMID: 33839163, DOI: 10.1016/j.kint.2021.03.020.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseKidney diseaseAnemia guidelinesHypoxia-inducible factor prolyl hydroxylase inhibitorOptimal anemia managementErythropoiesis-stimulating agentsTreatment of anemiaIron homeostasisSignificant adverse consequencesControversies ConferenceIron therapyAnemia managementRandomized trialsDiagnostic challengePatient outcomesEpidemiological studiesHydroxylase inhibitorTreatment targetsGlobal outcomeLatest evidenceDiseaseAnemiaPrevious recommendationsAdverse consequencesOngoing controversyGroup II GBCM Can Be Used Safely for Imaging in Stage 4/5 CKD Patients: COMMENTARY.
Abu-Alfa A. Group II GBCM Can Be Used Safely for Imaging in Stage 4/5 CKD Patients: COMMENTARY. Kidney360 2021, 2: 16-19. PMID: 35378016, PMCID: PMC8785741, DOI: 10.34067/kid.0006002020.Commentaries, Editorials and Letters
2020
KDIGO Controversies Conference on onco-nephrology: kidney disease in hematological malignancies and the burden of cancer after kidney transplantation
Małyszko J, Bamias A, Danesh F, Dębska-Ślizień A, Gallieni M, Gertz M, Kielstein J, Tesarova P, Wong G, Cheung M, Wheeler D, Winkelmayer W, Porta C, Participants C, Abu-Alfa A, Amer H, Beutel G, Chapman J, Chen X, Chudek J, Cosmai L, Danesi R, De Stefano F, Iseki K, Jaimes E, Jhaveri K, Jurczyszyn A, Kazancioğlu R, Kitchlu A, Kollmannsberger C, Lahoti A, Li Y, Macía M, Matsubara T, Mitropoulos D, Noiri E, Perazella M, Ronco P, Rosner M, Romeo M, Sprangers B, Stadler W, Stevens P, Tesař V, da Costa e Silva V, Vesole D, Vijayan A, Viklický O, Workeneh B, Yanagita M, Zakharova E. KDIGO Controversies Conference on onco-nephrology: kidney disease in hematological malignancies and the burden of cancer after kidney transplantation. Kidney International 2020, 98: 1407-1418. PMID: 33276867, DOI: 10.1016/j.kint.2020.07.012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsHematologic NeoplasmsHumansKidneyKidney TransplantationNeoplasmsNephrologyRenal Insufficiency, ChronicConceptsChronic kidney diseaseKidney diseaseHematological malignanciesControversies ConferenceKidney transplantationModerate stage chronic kidney diseaseKDIGO Controversies ConferenceAcute kidney injuryKidney transplant recipientsBurden of cancerKidney injuryTransplant recipientsKidney transplantRegistry analysisMultiple myelomaClinical challengeCancer riskGlobal outcomeMalignancyCancerPatientsDiseaseTransplantationBidirectional relationshipRiskKDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer
Porta C, Bamias A, Danesh F, Dębska-Ślizień A, Gallieni M, Gertz M, Kielstein J, Tesarova P, Wong G, Cheung M, Wheeler D, Winkelmayer W, Małyszko J, Participants C, Abu-Alfa A, Amer H, Beutel G, Chapman J, Chen X, Chudek J, Cosmai L, Danesi R, De Stefano F, Iseki K, Jaimes E, Jhaveri K, Jurczyszyn A, Kazancioğlu R, Kitchlu A, Kollmannsberger C, Lahoti A, Li Y, Macía M, Matsubara T, Mitropoulos D, Noiri E, Perazella M, Ronco P, Rosner M, Romeo M, Sprangers B, Stadler W, Stevens P, Tesař L, da Costa e Silva V, Vesole D, Vijayan A, Viklický O, Workeneh B, Yanagita M, Zakharova E. KDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer. Kidney International 2020, 98: 1108-1119. PMID: 33126977, DOI: 10.1016/j.kint.2020.06.046.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseSolid organ malignanciesControversies ConferenceKidney impairmentKidney diseaseKidney cancerKDIGO Controversies ConferenceSetting of malignancyIncidence of cancerAreas of controversyOrgan malignanciesTreatment landscapeKidney functionOncology patientsMedical oncologyPalliative careRenal issuesPatient outcomesNovel therapiesCritical careMalignancyAnticancer treatmentCancerPatientsCancer treatmentUse of Gadolinium-Based Contrast Agents in Kidney Disease Patients: Time for Change
Abu-Alfa AK. Use of Gadolinium-Based Contrast Agents in Kidney Disease Patients: Time for Change. American Journal Of Kidney Diseases 2020, 76: 436-439. PMID: 32283121, DOI: 10.1053/j.ajkd.2020.03.011.Commentaries, Editorials and LettersContrast MediaGadoliniumHumansMagnetic Resonance ImagingNephrogenic Fibrosing DermopathyRenal Insufficiency, Chronic
2019
Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
House A, Wanner C, Sarnak M, Piña I, McIntyre C, Komenda P, Kasiske B, Deswal A, deFilippi C, Cleland J, Anker S, Herzog C, Cheung M, Wheeler D, Winkelmayer W, McCullough P, Participants C, Abu-Alfa A, Amann K, Aonuma K, Appel L, Baigent C, Bakris G, Banerjee D, Boletis J, Bozkurt B, Butler J, Chan C, Costanzo M, Dubin R, Filippatos G, Gikonyo B, Gikonyo D, Hajjar R, Iseki K, Ishii H, Knoll G, Lenihan C, Lentine K, Lerma E, Macedo E, Mark P, Noiri E, Palazzuoli A, Pecoits-Filho R, Pitt B, Rigatto C, Rossignol P, Setoguchi S, Sood M, Störk S, Suri R, Szummer K, Tang S, Tangri N, Thompson A, Vijayaraghavan K, Walsh M, Wang A, Weir M. Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2019, 95: 1304-1317. PMID: 31053387, DOI: 10.1016/j.kint.2019.02.022.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseDialysis-dependent chronic kidney diseaseNondialysis chronic kidney diseaseHeart failureKidney diseaseEjection fractionGlobal outcomeKidney transplant patientsReduced ejection fractionControversies ConferenceTransplant patientsBreakout group discussionsDiseaseOutcomesFailureHFpEFPatientsGroup discussionsPrevalenceIncidenceDiagnosisPrevention
2018
Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Eckardt K, Bansal N, Coresh J, Evans M, Grams M, Herzog C, James M, Heerspink H, Pollock C, Stevens P, Tamura M, Tonelli M, Wheeler D, Winkelmayer W, Cheung M, Hemmelgarn B, Participants C, Abu-Alfa A, Anand S, Arici M, Ballew S, Block G, Burgos-Calderon R, Charytan D, Das-Gupta Z, Dwyer J, Fliser D, Froissart M, Gill J, Griffith K, Harris D, Huffman K, Inker L, Jager K, Jun M, Kalantar-Zadeh K, Kasiske B, Kovesdy C, Krane V, Lamb E, Lerma E, Levey A, Levin A, Mauro J, Nash D, Navaneethan S, O’Donoghue D, Obrador G, Pecoits-Filho R, Robinson B, Schäffner E, Segev D, Stengel B, Stenvinkel P, Tangri N, Tentori F, Tsukamoto Y, Turakhia M, Vazquez M, Wang A, Williams A. Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2018, 93: 1281-1292. PMID: 29656903, PMCID: PMC5998808, DOI: 10.1016/j.kint.2018.02.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsClinical Decision-MakingConsensusEvidence-Based MedicineGlomerular Filtration RateHumansKidneyNephrologyPrognosisRenal Insufficiency, ChronicRisk FactorsSeverity of Illness IndexConceptsGlomerular filtration rateKidney replacement therapyCKD G4Kidney failureFiltration rateRisk factorsGlobal outcomeTraditional CVD risk factorsCKD Prognosis ConsortiumCVD risk factorsCardiovascular disease eventsPrognosis of patientsOptimal therapeutic strategyControversies ConferenceCohort studyCVD outcomesHeart failureVariable prognosisClinical outcomesTherapeutic challengeKidney diseasePrognostic valueReplacement therapyInternational expert groupPatient preferencesKidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Swanepoel C, Atta M, D’Agati V, Estrella M, Fogo A, Naicker S, Post F, Wearne N, Winkler C, Cheung M, Wheeler D, Winkelmayer W, Wyatt C, Participants C, Abu-Alfa A, Adu D, Agodoa L, Alpers C, Arogundade F, Ashuntantang G, Bagnis C, Bhimma R, Brocheriou I, Cohen A, Cohen K, Cook H, de Seigneux S, Fabian J, Finkelstein F, Haas M, Hamzah L, Hendry B, Imonje V, Jennette J, Kimmel P, Klotman M, Klotman P, Larsen C, McCulloch M, Mosiane P, Nast C, Okpechi I, Ray P, Rosenberg A, Ross M, Ryom L, Truong L, Ulasi I, Vogt L, Zeier M. Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2018, 93: 545-559. PMID: 29398134, PMCID: PMC5983378, DOI: 10.1016/j.kint.2017.11.007.Peer-Reviewed Original ResearchConceptsHIV-positive individualsKidney diseaseAntiretroviral therapyHIV infectionImmune complex kidney diseaseKidney disease preventionHIV-associated nephropathyFocal segmental glomerulosclerosisUnique HIVKidney injuryOpportunistic infectionsHIV treatmentClinical guidelinesRenal pathologySegmental glomerulosclerosisGeneral populationRole of geneticsGlobal outcomeDisease preventionNatural historyInfectious diseasesDiseaseInfectionGenetic factorsPrevention
2013
Effects of weight reduction regimens and bariatric surgery on chronic kidney disease in obese patients
Abou-Mrad RM, Abu-Alfa AK, Ziyadeh FN. Effects of weight reduction regimens and bariatric surgery on chronic kidney disease in obese patients. American Journal Of Physiology. Renal Physiology 2013, 305: f613-f617. PMID: 23825072, DOI: 10.1152/ajprenal.00173.2013.BooksMeSH KeywordsAlbuminuriaAnimalsBariatric SurgeryDiet, ReducingExerciseGlomerular Filtration RateHumansObesityProteinuriaRenal Insufficiency, ChronicWeight LossConceptsChronic kidney diseaseKidney diseaseBariatric surgeryModerate chronic kidney diseaseWeight reduction regimensIntentional weight lossRenal functional changesWeight loss interventionHigh-protein dietGlomerular hyperfiltrationPerioperative complicationsObese patientsRenal damageLoss interventionAdvanced stageFunctional changesModest riskWeight lossDiseaseAlbuminuriaObesityPatientsSurgeryBeneficial reductionHypertension