2024
Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up
Dietz N, Kumar C, Elsamadicy A, Bjurström M, Wong K, Jamieson A, Sharma M, Wang D, Ugiliweneza B, Drazin D, Boakye M. Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up. Scientific Reports 2024, 14: 25340. PMID: 39455709, PMCID: PMC11511981, DOI: 10.1038/s41598-024-76248-6.Peer-Reviewed Original ResearchConceptsDegenerative lumbar pathologySurgical site infectionSpinal surgeryPolypharmacy groupSite infectionLumbar pathologyFollow-upMedical complicationsElective lumbar spinal surgeryLumbar spinal surgeryUrinary tract infectionDegenerative lumbar conditionsReturn to the emergency departmentTract infectionsNon-polypharmacy groupSurgical patientsLumbar conditionsSurgeryPatientsComplicationsPolypharmacyEmergency departmentPrescribed medicationsMarketScan datasetDegenerative conditions
2021
Effects of preoperative nutritional status on complications and readmissions after posterior lumbar decompression and fusion for spondylolisthesis: A propensity-score analysis
Elsamadicy AA, Havlik J, Reeves BC, Koo AB, Sherman J, Lo SL, Shin JH, Sciubba DM. Effects of preoperative nutritional status on complications and readmissions after posterior lumbar decompression and fusion for spondylolisthesis: A propensity-score analysis. Clinical Neurology And Neurosurgery 2021, 211: 107017. PMID: 34781222, DOI: 10.1016/j.clineuro.2021.107017.Peer-Reviewed Original ResearchConceptsUnplanned readmissionAdverse eventsSpine surgerySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseOccurrence of AEsPreoperative serum albumin levelQuality Improvement Program databaseMultivariate logistic regression analysisPosterior lumbar decompressionPreoperative nutritional statusHigh rateImprovement Program databaseRetrospective cohort studySerum albumin levelSignificant independent predictorsEffects of malnutritionLogistic regression analysisPropensity score analysisPropensity-score matchingMalnourished cohortMalnourished patientsPerioperative complicationsPostoperative complicationsLumbar decompressionPatient- and hospital-related risk factors for non-routine discharge after lumbar decompression and fusion for spondylolisthesis
Elsamadicy AA, Freedman IG, Koo AB, David W, Hengartner AC, Havlik J, Reeves BC, Hersh A, Pennington Z, Kolb L, Laurans M, Shin JH, Sciubba DM. Patient- and hospital-related risk factors for non-routine discharge after lumbar decompression and fusion for spondylolisthesis. Clinical Neurology And Neurosurgery 2021, 209: 106902. PMID: 34481141, DOI: 10.1016/j.clineuro.2021.106902.Peer-Reviewed Original ResearchConceptsNon-routine dischargeDependent functional statusAdverse eventsIndependent predictorsUnplanned readmissionLonger LOSSpinal decompressionLumbar spondylolisthesisFemale sexFunctional statusSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseNon-Hispanic black race/ethnicityHospital-related risk factorsQuality Improvement Program databaseNon-Hispanic black raceICD-9-CM diagnosisBlack race/ethnicityMultivariate logistic regression modelNon-home dischargeHospital-related factorsImprovement Program databaseRetrospective cohort studyLength of stayProcedural Coding SystemFenestrated pedicle screws for thoracolumbar instrumentation in patients with poor bone quality: Case series and systematic review of the literature
Ehresman J, Pennington Z, Elsamadicy AA, Hersh A, Lubelski D, Lehner K, Cottrill E, Schilling A, Lakomkin N, Ahmed AK, Lo SF, Sciubba DM. Fenestrated pedicle screws for thoracolumbar instrumentation in patients with poor bone quality: Case series and systematic review of the literature. Clinical Neurology And Neurosurgery 2021, 206: 106675. PMID: 34020324, DOI: 10.1016/j.clineuro.2021.106675.Peer-Reviewed Original ResearchConceptsPulmonary cement embolismFenestrated pedicle screwsCement leakageBone qualityCement embolismInstrumented fusionHardware looseningOsteoporotic fracturesPedicle screwsSystematic reviewSymptomatic pulmonary cement embolismNon-augmented patientsSingle-surgeon seriesDegenerative spine diseaseHigh-quality evidencePoor bone qualityEndpoints of interestLow reported ratesPathologic fractureCase seriesSpine metastasesFenestrated screwsSpine diseasePRISMA guidelinesPatients
2018
Minimally Invasive Lateral Access Surgery and Reoperation Rates: A Multi-Institution Retrospective Review of 2060 Patients
Nayar G, Wang T, Sankey EW, Berry-Candelario J, Elsamadicy AA, Back A, Karikari I, Isaacs R. Minimally Invasive Lateral Access Surgery and Reoperation Rates: A Multi-Institution Retrospective Review of 2060 Patients. World Neurosurgery 2018, 116: e744-e749. PMID: 29787875, DOI: 10.1016/j.wneu.2018.05.082.Peer-Reviewed Original ResearchConceptsRate of reoperationLateral access surgeryLumbar spine surgeryMore comorbiditiesSurgical approachSpine surgeryDecompressive lumbar spine surgeryElective lumbar spinal surgeryMulti-institution retrospective reviewAccess surgeryLower body mass indexLumbar spinal surgeryBody mass indexOpen posterior approachHealth care systemOnly significant predictorAdditional readmissionsLT cohortOP cohortOP surgeryReoperation ratePatient demographicsSurgical complicationsRetrospective reviewMass indexInfluence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery.
Elsamadicy AA, Kemeny H, Adogwa O, Sankey EW, Goodwin CR, Yarbrough CK, Lad SP, Karikari IO, Gottfried ON. Influence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery. Journal Of Neurosurgery Spine 2018, 29: 40-45. PMID: 29701564, DOI: 10.3171/2017.12.spine171079.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanDiagnostic Self EvaluationDisability EvaluationElective Surgical ProceduresFemaleHealth StatusHealthcare DisparitiesHumansLumbar VertebraeMaleMiddle AgedPainPatient Reported Outcome MeasuresPatient SatisfactionPrevalenceProspective StudiesRetrospective StudiesSelf ConceptTime FactorsWhite PeopleConceptsElective lumbar spine surgeryPatient-reported outcomesLumbar spine surgerySpine surgeryPatient satisfactionRacial disparitiesPatient demographicsReadmission ratesWhite patientsAA patientsMedical recordsLong-term patient-reported outcomesOverall patient-reported outcomeGreater body mass indexBaseline patient demographicsInferior surgical outcomesVAS-LP scoresPatient-reported satisfactionOverall patient satisfactionBody mass indexVisual analog scaleAfrican American patientsPatient-specific factorsPatient satisfaction measuresPerception of healthInterdisciplinary Care Model Independently Decreases Use of Critical Care Services After Corrective Surgery for Adult Degenerative Scoliosis
Adogwa O, Elsamadicy AA, Sergesketter AR, Ongele M, Vuong V, Khalid S, Moreno J, Cheng J, Karikari IO, Bagley CA. Interdisciplinary Care Model Independently Decreases Use of Critical Care Services After Corrective Surgery for Adult Degenerative Scoliosis. World Neurosurgery 2018, 111: e845-e849. PMID: 29317368, DOI: 10.1016/j.wneu.2017.12.180.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCase ManagementClinical ProtocolsCohort StudiesCritical CareDecompression, SurgicalFemaleGeriatricsHumansLumbar VertebraeMaleNeurosurgical ProceduresPatient Care TeamPostoperative CarePostoperative ComplicationsRetrospective StudiesScoliosisSpinal FusionTreatment OutcomeConceptsElderly patientsCritical care servicesICU transferIndependent predictorsCorrective surgeryFusion surgeryComanagement modelSpine surgeryCare servicesComplex lumbar spine surgeryTeam approachIntensive care unit resourcesPeri-operative optimizationSenior Health (POSH) programDuration of surgeryLumbar spine surgeryInterdisciplinary care modelLong-term outcomesLumbar fusion surgeryMajor academic medical centerAdult degenerative scoliosisAcademic medical centerInterdisciplinary team approachPOSH cohortHospital course
2017
The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion
Adogwa O, Elsamadicy AA, Sergesketter A, Oyeyemi D, Galan D, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion. World Neurosurgery 2017, 110: e266-e270. PMID: 29109065, DOI: 10.1016/j.wneu.2017.10.147.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCKD groupPatient demographicsKidney diseaseLumbar arthrodesisPreoperative chronic kidney diseaseInferior perioperative outcomesLumbar spine decompressionPostoperative complication profileLength of surgeryPostoperative complication rateEpisode of deliriumUrinary tract infectionDeep vein thrombosisBody mass indexIntensive care unitMajor academic institutionPerioperative complicationsPerioperative outcomesPostoperative complicationsPrimary endpointAdult patientsComplication rateLumbar decompressionPostoperative outcomesGeriatric comanagement reduces perioperative complications and shortens duration of hospital stay after lumbar spine surgery: a prospective single-institution experience.
Adogwa O, Elsamadicy AA, Vuong VD, Moreno J, Cheng J, Karikari IO, Bagley CA. Geriatric comanagement reduces perioperative complications and shortens duration of hospital stay after lumbar spine surgery: a prospective single-institution experience. Journal Of Neurosurgery Spine 2017, 27: 670-675. PMID: 28960161, DOI: 10.3171/2017.5.spine17199.Peer-Reviewed Original ResearchConceptsLumbar spine surgeryHospital stayPOSH cohortElderly patientsSpine surgeryGeriatric comanagementPerioperative complicationsComplex lumbar spine surgeryElective lumbar spine surgeryMedical comorbid conditionsSenior Health (POSH) programDays of dischargeElective spinal surgerySingle institution experienceMajority of patientsNursing home admissionLumbar fusion surgeryResults One hundred twentyMajor academic medical centerAdult degenerative scoliosisAcademic medical centerHospital complicationsSurgical screeningPostoperative complicationsBaseline characteristicsImpact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients
Elsamadicy AA, Reddy GB, Nayar G, Sergesketter A, Zakare-Fagbamila R, Karikari IO, Gottfried ON. Impact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients. World Neurosurgery 2017, 107: 952-958. PMID: 28743671, DOI: 10.1016/j.wneu.2017.07.082.Peer-Reviewed Original ResearchConceptsElective lumbar spine surgeryLumbar spine surgeryVisual analog scaleSpine surgeryMale cohortPerception of healthFemale cohortAnalog scaleMean changeBaseline patient-reported outcome measuresVisual analog scale leg painEuroQol 5 dimensions questionnairePatient-reported outcome measuresPatient-reported outcome instrumentsBaseline patient demographicsLonger hospital stayOswestry Disability IndexSingle institutional studyOverall patient satisfactionLong-term patientsPatient-reported outcomesPatient satisfaction measuresPaucity of dataSpine OutcomesDisability Index
2016
Patient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery
Elsamadicy AA, Adogwa O, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Patient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery. World Neurosurgery 2016, 96: 148-151. PMID: 27593714, DOI: 10.1016/j.wneu.2016.08.097.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexCase-Control StudiesComorbidityDecompression, SurgicalElective Surgical ProceduresFemaleHumansLength of StayLogistic ModelsLumbar VertebraeMaleMiddle AgedMultivariate AnalysisObesityPatient ReadmissionPneumoniaPostoperative ComplicationsRadiculopathyRisk FactorsSpinal DiseasesSpinal FusionSpinal StenosisSpondylolisthesisSurgical Wound InfectionUrinary Tract InfectionsConceptsElective spine surgeryBody mass indexPreoperative body mass indexMultivariate logistic regression analysisDays of dischargeIndependent risk factorHospital readmissionSpine surgeryLogistic regression analysisPreoperative obesityReadmission ratesIndependent predictorsMass indexRisk factorsEarly unplanned hospital readmissionPatient body mass indexUnplanned hospital readmissionPostoperative complication rateAppropriate risk stratificationPrevalence of obesityMajor academic medical centerAcademic medical centerRegression analysisHealth care climateIndex surgeryDo measures of surgical effectiveness at 1 year after lumbar spine surgery accurately predict 2-year outcomes?
Adogwa O, Elsamadicy AA, Han JL, Cheng J, Karikari I, Bagley CA. Do measures of surgical effectiveness at 1 year after lumbar spine surgery accurately predict 2-year outcomes? Journal Of Neurosurgery Spine 2016, 25: 689-696. PMID: 26722957, DOI: 10.3171/2015.8.spine15476.Peer-Reviewed Original ResearchConceptsTransforaminal lumbar interbody fusionLumbar spine surgeryAnterior lumbar interbody fusionLong-term outcomesLateral interbody fusionLumbar interbody fusionSpine surgeryInterbody fusionSurgical effectivenessOutcome measuresSF-36 physical component summary scorePhysical component summary scoreLongitudinal assessmentPatient-reported outcome instrumentsAchievement of MCIDMultiinstitutional prospective studyVAS leg painComponent summary scoresClinical outcome dataPatient-centered measuresLogistic regression modelingIneffective patient careInstitutional registryOutcomes RegistrySF-36
2015
Effects of Psoas Muscle Thickness on Outcomes of Lumbar Fusion Surgery
Verla T, Adogwa O, Elsamadicy A, Moreno JR, Farber H, Cheng J, Bagley CA. Effects of Psoas Muscle Thickness on Outcomes of Lumbar Fusion Surgery. World Neurosurgery 2015, 87: 283-289. PMID: 26619920, DOI: 10.1016/j.wneu.2015.11.022.Peer-Reviewed Original ResearchConceptsPsoas muscle thicknessLumbar fusion surgeryFusion surgeryMuscle thicknessPsoas muscleSpinal stabilizationVisual analog scale pain scoreHip flexor weaknessScale pain scoresPreoperative magnetic resonanceInterbody fusion surgeryLumbar intervertebral spaceSpecific clinical outcomesWarrants further investigationEarly ambulationPain scoresAdult patientsFlexor weaknessPostoperative rehabilitationRetrospective reviewClinical outcomesHospital recordsSurgical optionsLumbar pathologyFunctional outcomeDo obese patients have worse outcomes after direct lateral interbody fusion compared to non-obese patients?
Adogwa O, Farber SH, Fatemi P, Desai R, Elsamadicy A, Cheng J, Bagley C, Gottfried O, Isaacs RE. Do obese patients have worse outcomes after direct lateral interbody fusion compared to non-obese patients? Journal Of Clinical Neuroscience 2015, 25: 54-57. PMID: 26549673, DOI: 10.1016/j.jocn.2015.05.056.Peer-Reviewed Original ResearchConceptsDirect lateral interbody fusionNon-obese patientsOswestry Disability IndexLateral interbody fusionObese patientsLeg painPostoperative complicationsComplication rateInterbody fusionPain numerical rating scoresVisual analog scale (VAS) backLumbar spinal fusion surgeryDegenerative diseasesAnterior thigh numbnessIncidence of durotomySimilar complication profilePostoperative complication rateLong-term outcomesNumerical rating scoreCerebrospinal fluid leakSpinal fusion surgeryPsoas hematomaThigh numbnessDisability IndexNerve injury