2024
Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up
Dietz N, Kumar C, Elsamadicy A, Bjurström M, Wong K, Jamieson A, Sharma M, Wang D, Ugiliweneza B, Drazin D, Boakye M. Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up. Scientific Reports 2024, 14: 25340. PMID: 39455709, PMCID: PMC11511981, DOI: 10.1038/s41598-024-76248-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedElective Surgical ProceduresFemaleFollow-Up StudiesHumansLumbar VertebraeMaleMiddle AgedPolypharmacyPostoperative ComplicationsSurgical Wound InfectionConceptsDegenerative lumbar pathologySurgical site infectionSpinal surgeryPolypharmacy groupSite infectionLumbar pathologyFollow-upMedical complicationsElective lumbar spinal surgeryLumbar spinal surgeryUrinary tract infectionDegenerative lumbar conditionsReturn to the emergency departmentTract infectionsNon-polypharmacy groupSurgical patientsLumbar conditionsSurgeryPatientsComplicationsPolypharmacyEmergency departmentPrescribed medicationsMarketScan datasetDegenerative conditions
2021
A Web-Based Calculator for Predicting the Occurrence of Wound Complications, Wound Infection, and Unplanned Reoperation for Wound Complications in Patients Undergoing Surgery for Spinal Metastases
Hersh AM, Feghali J, Hung B, Pennington Z, Schilling A, Antar A, Patel J, Ehresman J, Cottrill E, Lubelski D, Elsamadicy AA, Goodwin CR, Lo SL, Sciubba DM. A Web-Based Calculator for Predicting the Occurrence of Wound Complications, Wound Infection, and Unplanned Reoperation for Wound Complications in Patients Undergoing Surgery for Spinal Metastases. World Neurosurgery 2021, 155: e218-e228. PMID: 34403800, DOI: 10.1016/j.wneu.2021.08.041.Peer-Reviewed Original ResearchConceptsLow platelet countWound complicationsPlatelet countUnplanned reoperationWound infectionRevision surgeryWeb-based calculatorIncision lengthHigher CCIHigher Charlson comorbidity indexSingle comprehensive cancer centerKarnofsky Performance Scale scoreLonger incision lengthCharlson Comorbidity IndexWound-related complicationsIndependent predictive factorsSurgical site infectionMultivariable logistic regressionPerformance Scale scoreComprehensive cancer centerOptimism-corrected areaPoor health statusComorbidity indexIndex surgeryMetastasis surgery
2020
Laser Interstitial Thermotherapy for Treatment of Symptomatic Peritumoral Edema After Radiosurgery for Meningioma
Hong CS, Beckta JM, Kundishora AJ, Elsamadicy AA, Chiang VL. Laser Interstitial Thermotherapy for Treatment of Symptomatic Peritumoral Edema After Radiosurgery for Meningioma. World Neurosurgery 2020, 136: 295-300. PMID: 32001396, DOI: 10.1016/j.wneu.2020.01.143.Peer-Reviewed Original ResearchConceptsSymptomatic peritumoral edemaPeritumoral edemaLaser interstitial thermotherapySurgical resectionGrade IOpen surgical resectionEffective therapeutic modalityViable alternative treatmentInterstitial thermotherapyExperienced resolutionCorticosteroid therapyIntraoperative biopsyRefractory casesConservative managementMost patientsLesion recurrenceMedical therapyRadiation necrosisUnderlying lesionSurgical interventionWound infectionTherapeutic modalitiesRadiosurgical treatmentAlternative treatmentFrontotemporal lesions
2018
Does Nasal Carriage of Staphylococcus aureus Increase the Risk of Postoperative Infections After Elective Spine Surgery: Do Most Infections Occur in Carriers?
Adogwa O, Vuong VD, Elsamadicy AA, Lilly DT, Desai SA, Khalid S, Cheng J, Bagley CA. Does Nasal Carriage of Staphylococcus aureus Increase the Risk of Postoperative Infections After Elective Spine Surgery: Do Most Infections Occur in Carriers? World Neurosurgery 2018, 116: e519-e524. PMID: 29772370, DOI: 10.1016/j.wneu.2018.05.025.Peer-Reviewed Original ResearchConceptsSurgical site infectionElective spine surgeryWound infectionNasal colonizationSite infectionSpine surgeryCases of SSIPost-operative surgical site infectionDirect medical record reviewAdult spinal deformity surgeryProspective multi-institutional studyLocal vancomycin powderPostoperative wound infectionDeep wound infectionHistory of diabetesMajority of patientsMedical record reviewDay of surgeryBody mass indexStandard deviation agePost-operative infectionSpinal deformity surgeryMulti-institutional studyBaseline characteristicsNasal carriage
2017
Prophylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases.
Adogwa O, Elsamadicy AA, Sergesketter A, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Prophylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases. Journal Of Neurosurgery Spine 2017, 27: 328-334. PMID: 28665245, DOI: 10.3171/2017.2.spine161310.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsAntibiotic ProphylaxisFemaleFollow-Up StudiesHumansMaleMiddle AgedPowdersRetrospective StudiesSpinal CurvaturesSpineSurgical Wound InfectionVancomycinConceptsSurgical site infectionMean body mass indexIntraoperative vancomycin powderVancomycin powderWound infectionAdult patientsProphylactic useCases of SSIPatients' mean body mass indexMicrobiological patternDirect medical record reviewPostoperative surgical site infectionDuke University Medical CenterDeep wound infectionEmpirical antibiotic therapyHistory of diabetesAdverse clinical outcomesMedical record reviewConsecutive surgical casesDay of surgeryBody mass indexSpinal deformity surgeryUniversity Medical CenterRandomized control trialHealth care systemPost-operative delirium is an independent predictor of 30-day hospital readmission after spine surgery in the elderly (≥65years old): A study of 453 consecutive elderly spine surgery patients
Elsamadicy AA, Wang TY, Back AG, Lydon E, Reddy GB, Karikari IO, Gottfried ON. Post-operative delirium is an independent predictor of 30-day hospital readmission after spine surgery in the elderly (≥65years old): A study of 453 consecutive elderly spine surgery patients. Journal Of Clinical Neuroscience 2017, 41: 128-131. PMID: 28262398, DOI: 10.1016/j.jocn.2017.02.040.Peer-Reviewed Original ResearchConceptsPost-operative deliriumIndependent risk factorSpine surgeryElderly patientsReadmission ratesHospital readmissionRisk factorsDelirium patientsComplication rateIndependent predictorsPost-operative complication rateSuperficial surgical site infectionMultivariate logistic regression analysisDuke University Medical CenterConsecutive elderly patientsSpine surgery patientsSurgical site infectionLogistic regression analysisUniversity Medical CenterLower healthcare costsDSM-V criteriaHospital stayUnplanned readmissionPatient demographicsSurgery patients
2016
Patient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery
Elsamadicy AA, Adogwa O, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Patient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery. World Neurosurgery 2016, 96: 148-151. PMID: 27593714, DOI: 10.1016/j.wneu.2016.08.097.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexCase-Control StudiesComorbidityDecompression, SurgicalElective Surgical ProceduresFemaleHumansLength of StayLogistic ModelsLumbar VertebraeMaleMiddle AgedMultivariate AnalysisObesityPatient ReadmissionPneumoniaPostoperative ComplicationsRadiculopathyRisk FactorsSpinal DiseasesSpinal FusionSpinal StenosisSpondylolisthesisSurgical Wound InfectionUrinary Tract InfectionsConceptsElective spine surgeryBody mass indexPreoperative body mass indexMultivariate logistic regression analysisDays of dischargeIndependent risk factorHospital readmissionSpine surgeryLogistic regression analysisPreoperative obesityReadmission ratesIndependent predictorsMass indexRisk factorsEarly unplanned hospital readmissionPatient body mass indexUnplanned hospital readmissionPostoperative complication rateAppropriate risk stratificationPrevalence of obesityMajor academic medical centerAcademic medical centerRegression analysisHealth care climateIndex surgery