Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up
Dietz N, Kumar C, Elsamadicy A, Bjurström M, Wong K, Jamieson A, Sharma M, Wang D, Ugiliweneza B, Drazin D, Boakye M. Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up. Scientific Reports 2024, 14: 25340. PMID: 39455709, PMCID: PMC11511981, DOI: 10.1038/s41598-024-76248-6.Peer-Reviewed Original ResearchConceptsDegenerative lumbar pathologySurgical site infectionSpinal surgeryPolypharmacy groupSite infectionLumbar pathologyFollow-upMedical complicationsElective lumbar spinal surgeryLumbar spinal surgeryUrinary tract infectionDegenerative lumbar conditionsReturn to the emergency departmentTract infectionsNon-polypharmacy groupSurgical patientsLumbar conditionsSurgeryPatientsComplicationsPolypharmacyEmergency departmentPrescribed medicationsMarketScan datasetDegenerative conditionsDecompression Alone Versus Interspinous/Interlaminar Device Placement for Degenerative Lumbar Pathologies: Systematic Review and Meta-Analysis
Pennington Z, Lakomkin N, Mikula A, Elsamadicy A, Astudillo Potes M, Fogelson J, Grossbach A, Elder B. Decompression Alone Versus Interspinous/Interlaminar Device Placement for Degenerative Lumbar Pathologies: Systematic Review and Meta-Analysis. World Neurosurgery 2024, 185: 417-434.e3. PMID: 38508384, DOI: 10.1016/j.wneu.2024.03.054.Peer-Reviewed Original ResearchPatient-reported outcomesDecompression-aloneDegenerative lumbar pathologyPain improvementInterlaminar deviceLumbar pathologySF-36 physical component scoreLeg pain improvementDisease-specific patient-reported outcomeBack pain improvementPhysical component scorePhysical function scoresTotal care costsEQ-5D scoresTotal treatment costsSymptom severity scoresReoperation ratePerioperative complicationsConventional surgerySF-36Care costsFollow-upComponent scoresSeverity scoreDevice placement