2024
Risk factors for MACE and bleeding in atrial fibrillation patients undergoing surgery: Insights from the bridge trial
Shu L, Jack N, de Havenon A, Goldstein E, Khan F, Nguyen T, Henninger N, Siegler J, Stretz C, Perelstein E, Kala N, Rana M, Furie K, Douketis J, Yaghi S. Risk factors for MACE and bleeding in atrial fibrillation patients undergoing surgery: Insights from the bridge trial. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107839. PMID: 38944363, DOI: 10.1016/j.jstrokecerebrovasdis.2024.107839.Peer-Reviewed Original ResearchMajor adverse cardiovascular eventsSymptomatic bleedingBridging therapyRisk factorsAtrial fibrillationLow-molecular-weight heparin bridging therapyTemporary interruption of warfarin therapyInterruption of warfarin therapyNonsteroidal anti-inflammatory drug useElective proceduresAnti-inflammatory drug useElective invasive proceduresHeparin bridging therapyRisk of adverse outcomesAdverse cardiovascular eventsPerioperative risk stratificationCox regression modelsIdentified risk factorsPost hoc analysisPatient undergoes surgeryLogistic stepwise regressionWarfarin therapyBridging anticoagulationAF patientsBleeding outcomes
2023
Perioperative Acute Ischemic Stroke in Patients with Atrial Fibrillation
Shu L, Jiang W, Xiao H, Henninger N, Nguyen T, Siegler J, de Havenon A, Goldstein E, Mandel D, Rana M, Al‐Mufti F, Frontera J, Furie K, Yaghi S. Perioperative Acute Ischemic Stroke in Patients with Atrial Fibrillation. Annals Of Neurology 2023, 94: 321-329. PMID: 37183768, DOI: 10.1002/ana.26678.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeAtrial fibrillationPerioperative acute ischemic strokeDiagnosis-related groupsRisk factors-VASc scoreActive cancerHigher CHA<sub>2</sub> DS<sub>2</sub> VASc score. TheElective proceduresInternational Classification of DiseasesRisk factors of acute ischemic strokeScoring systemIschemic strokeClassification of DiseasesNeurological surgeryDays of dischargeLogistic regression modelsNationwide Readmissions DatabaseElective surgical proceduresAnticoagulant therapyInternational ClassificationPeriprocedural periodRenal failureSurgical typeAdult patients