Annexin-A5 monomer as a membrane repair agent for the treatment of renal ischemia-reperfusion injury
Dong Y, Jia Z, Kang B, Zhang W. Annexin-A5 monomer as a membrane repair agent for the treatment of renal ischemia-reperfusion injury. Molecular Biology Reports 2024, 51: 679. PMID: 38796668, DOI: 10.1007/s11033-024-09606-2.Peer-Reviewed Original ResearchConceptsRenal ischemia-reperfusion injuryIschemia-reperfusion injuryEffect of anxA5Bilateral renal IRIBackgroundRenal ischemia-reperfusion injuryProtective effectTreatment of renal ischemia-reperfusion injuryAcute kidney injurySimulated ischemia-reperfusion injuryEpithelial cell membranesHK-2 cellsMechanism of actionKidney injurySD ratsIn vitro experimentsTherapeutic effectPrevent cell deathMeasure cellular activityKidney structureAnnexin A5HK-2AnxA5In vitroCell deathCell membrane integrity