The Unique-5 and -6 Motifs of ZO-1 Regulate Tight Junction Strand Localization and Scaffolding Properties
Fanning AS, Little BP, Rahner C, Utepbergenov D, Walther Z, Anderson JM. The Unique-5 and -6 Motifs of ZO-1 Regulate Tight Junction Strand Localization and Scaffolding Properties. Molecular Biology Of The Cell 2006, 18: 721-731. PMID: 17182847, PMCID: PMC1805089, DOI: 10.1091/mbc.e06-08-0764.Peer-Reviewed Original ResearchConceptsProper cellular locationMAGUK protein familyZO-1Tight junction transmembrane proteinsGUK domainTight junctionsMAGUK proteinsProtein familyScaffolding functionsTransmembrane proteinComplex protein bindingCellular locationLateral cell membranesRegulatory functionsC-terminalCultured cellsCell membraneJunction strandsVariable regionsMotifProteinBindingU5Protein bindingMAGUKs