2019
Endogenous development of Cystoisospora belli in intestinal and biliary epithelium of humans
Dubey JP, Evason KJ, Walther Z. Endogenous development of Cystoisospora belli in intestinal and biliary epithelium of humans. Parasitology 2019, 146: 865-872. PMID: 30859916, DOI: 10.1017/s003118201900012x.Peer-Reviewed Original ResearchConceptsBiliary epitheliumC. belliEpithelial cellsCystoisospora belliSingle parasitophorous vacuoleDuodenal biopsiesBiliary tractDepressed immunityPAS-positive granulesHistopathologic diagnosisHost epithelial cellsBiopsy samplesDigestive disordersSame PVParasitophorous vacuoleParasite multipliesCertain inclusionTransmission cycleEpitheliumCoccidian parasitesAsexual stagesBelliMerozoitesCellsOocysts
2008
A PDZ‐Binding Motif Controls Basolateral Targeting of Syndecan‐1 Along the Biosynthetic Pathway in Polarized Epithelial Cells
Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I. A PDZ‐Binding Motif Controls Basolateral Targeting of Syndecan‐1 Along the Biosynthetic Pathway in Polarized Epithelial Cells. Traffic 2008, 9: 1915-1924. PMID: 18764819, PMCID: PMC2820280, DOI: 10.1111/j.1600-0854.2008.00805.x.Peer-Reviewed Original ResearchConceptsPolarized epithelial cellsBiosynthetic pathwayPDZ domain-containing proteinsType II PDZDomain-containing proteinsPDZ-Binding MotifSyndecan-1Cell surface proteoglycansEpithelial cellsBasolateral targetingNormal epithelial morphologyBasolateral domainMotif leadPlasma membranePDZBasolateral localizationSurface proteoglycansBasolateral surfaceApical surfaceEpithelial morphologyMotifPotential rolePathwayCellsMislocalization