Yan Huang, PhD
Associate Research Scientist in Medicine (Comparative Medicine)Cards
About
Research
Publications
2026
Vitamin E Protects Against Gestational Deep Vein Thrombosis: The Role of Inhibiting Endothelial Ferroptosis
Zhang J, Du R, Sun W, Huang Y, Zhang Y, Bayibieke K, Chen L, Lu T, Ni H, Zhong X, Chen C, Sun B, Xu Y, Cheng X. Vitamin E Protects Against Gestational Deep Vein Thrombosis: The Role of Inhibiting Endothelial Ferroptosis. Drug Design Development And Therapy 2026, 20: 600777. PMID: 42699317, PMCID: PMC13544368, DOI: 10.2147/dddt.s600777.Peer-Reviewed Original ResearchMβCD@HA-Ad nanoparticles inhibit pancreatic cancer progression by targeting Caveolin-1/Piezo1/PLA2G4A-mediated lipid reprogramming
Xue Y, Chen X, Jiang X, Guo Y, Huang Y, Wang Z, Lu Y, Yang Y, Wang D. MβCD@HA-Ad nanoparticles inhibit pancreatic cancer progression by targeting Caveolin-1/Piezo1/PLA2G4A-mediated lipid reprogramming. Journal Of Controlled Release 2026, 398: 115223. PMID: 42532144, DOI: 10.1016/j.jconrel.2026.115223.Peer-Reviewed Original ResearchMapping AAV capsid sequences to functions through function-guided in silico evolution
Guo B, Zheng H, Lin X, Jiang H, Mo A, Wei H, Zhang R, Yuan Y, Wu Y, Li H, Zhang Y, Song Z, Ni X, Huang Y, Yu B, Yang Y, Gu X, Chen Z, Cheng N, Wang X. Mapping AAV capsid sequences to functions through function-guided in silico evolution. Cell Press Blue 2026, 1: 100016. DOI: 10.1016/j.cpblue.2026.100016.Peer-Reviewed Original ResearchtRF-34-P4R8YP9LON4VHM may serve as a promising potential diagnostic biomarker for hepatocellular carcinoma
Guo Y, Huang M, Lu Y, Xu T, Ge X, Huang Y, Zong W, Ni K. tRF-34-P4R8YP9LON4VHM may serve as a promising potential diagnostic biomarker for hepatocellular carcinoma. Scientific Reports 2026, 16: 19412. PMID: 42045304, PMCID: PMC13287578, DOI: 10.1038/s41598-026-49634-5.Peer-Reviewed Original ResearchLactylation Converts ABHD6 into a Mitochondrial Regulator That Drives Lenvatinib Resistance in Hepatocellular Carcinoma
Sun Y, Luo C, Yang H, Ye J, Song F, Yi Q, Zou W, Huang Y, Fan X, Wang L, Zhang Y, Ding Q, Zhu Y, Tang Z. Lactylation Converts ABHD6 into a Mitochondrial Regulator That Drives Lenvatinib Resistance in Hepatocellular Carcinoma. Cancer Research 2026, 86: 2970-2989. PMID: 41861279, PMCID: PMC13266342, DOI: 10.1158/0008-5472.can-25-4282.Peer-Reviewed Original ResearchEngineered LINC MIR503HG-loaded extracellular vesicles maintain stemness and pluripotency during long-term hiPSCs culture
Zhu J, Zhu X, Feng W, Jin Y, Ge X, Li Y, Xue X, Wang Z, Xu Y, Huang Y. Engineered LINC MIR503HG-loaded extracellular vesicles maintain stemness and pluripotency during long-term hiPSCs culture. Bioactive Materials 2026, 58: 650-665. PMID: 41551196, PMCID: PMC12809747, DOI: 10.1016/j.bioactmat.2025.12.023.Peer-Reviewed Original Research
2025
Management of preoperative biliary drainage on postoperative complications and mortality in patients with different degrees of obstructive jaundice undergoing pancreaticoduodenectomy
Guo Q, Wan J, Huang Y, Wang D, Chen Q, Wu C, Fan X, Wang P, Lu Y. Management of preoperative biliary drainage on postoperative complications and mortality in patients with different degrees of obstructive jaundice undergoing pancreaticoduodenectomy. Annals Of Hepato-Biliary-Pancreatic Surgery 2025, 29: 405-414. PMID: 41024413, PMCID: PMC12643813, DOI: 10.14701/ahbps.25-123.Peer-Reviewed Original ResearchAG73-GelMA/AlgMA hydrogels provide a stable microenvironment for the generation of pancreatic progenitor organoids
Wan J, Xu Y, Qi T, Xue X, Li Y, Huang M, Guo Y, Guo Q, Lu Y, Huang Y. AG73-GelMA/AlgMA hydrogels provide a stable microenvironment for the generation of pancreatic progenitor organoids. Journal Of Nanobiotechnology 2025, 23: 149. PMID: 40016740, PMCID: PMC11866579, DOI: 10.1186/s12951-025-03266-5.Peer-Reviewed Original ResearchMatrix stiffness boosts PDAC chemoresistance via SCD1-dependent lipid metabolic reprogramming
Zhang X, Zhu B, Yan J, Chen X, Wu D, Wang Z, Guan X, Huang Y, Zhao Y, Yang Y, Guo Y. Matrix stiffness boosts PDAC chemoresistance via SCD1-dependent lipid metabolic reprogramming. Regenerative Biomaterials 2025, 12: rbaf056. PMID: 40741620, PMCID: PMC12308179, DOI: 10.1093/rb/rbaf056.Peer-Reviewed Original Research
2024
Vascular endothelial cells derived from transgene-free pig induced pluripotent stem cells for vascular tissue engineering
Batty L, Park J, Qin L, Riaz M, Lin Y, Xu Z, Gao X, Li X, Lopez C, Zhang W, Hoareau M, Fallon M, Huang Y, Luo H, Luo J, Ménoret S, Li P, Jiang Z, Smith P, Sachs D, Tellides G, Anegon I, Pober J, Liu P, Qyang Y. Vascular endothelial cells derived from transgene-free pig induced pluripotent stem cells for vascular tissue engineering. Acta Biomaterialia 2024, 193: 171-184. PMID: 39681154, PMCID: PMC12212065, DOI: 10.1016/j.actbio.2024.12.033.Peer-Reviewed Original Research
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