2023
Serum BDNF levels and state anxiety are associated with somatic symptoms in patients with panic disorder
Li J, Li R, Li D, Zhang J, Luo X, Zhang Y. Serum BDNF levels and state anxiety are associated with somatic symptoms in patients with panic disorder. Frontiers In Psychiatry 2023, 14: 1168771. PMID: 37533888, PMCID: PMC10393281, DOI: 10.3389/fpsyt.2023.1168771.Peer-Reviewed Original ResearchPanic Disorder Severity Scale-Chinese VersionSerum BDNF levelsState-Trait Anxiety InventoryBDNF levelsSomatic symptomsPanic disorderPHQ-15State anxietyPD patientsSerum BDNFBaseline serum BDNF levelsHealthy controlsAssociated with somatic symptomsAnxiety-related symptomsAnxiety-related variablesMeasure somatic symptomsPHQ-15 scoresEscitalopram treatmentPanic severityAssess panicNinety PD patientsState-TraitAnxiety InventoryPanicPartial correlation analysis
2022
Sensory gating deficits and childhood trauma in the onset of first-episode schizophrenia
Wang L, Zeng W, Yin Y, Zhou Y, Huang J, Zhang P, Chen S, Fan H, Luo X, Tan S, Wang Z, Li C, Tian B, Tian L, Ma C, Li Y, Tan Y. Sensory gating deficits and childhood trauma in the onset of first-episode schizophrenia. Asian Journal Of Psychiatry 2022, 80: 103385. PMID: 36542893, DOI: 10.1016/j.ajp.2022.103385.Peer-Reviewed Original ResearchConceptsSensory gating deficitsFirst-episode schizophreniaGating deficitsS1-S2 differenceHealth controlsChildhood Trauma QuestionnaireChildhood trauma experiencesChildhood traumaS2/S1 ratioOnset of schizophreniaTrauma experiencesP50 sensory gatingSevere childhood traumaEmotional neglectSchizophrenia onsetS1 ratioSensory gatingAuditory conditioningEarly interventionCTQ totalSchizophreniaTraumaTrauma QuestionnaireStimulus paradigmPartial correlation analysis
2021
Kynurenine metabolism and metabolic syndrome in patients with schizophrenia
Zhang P, Huang J, Gou M, Zhou Y, Tong J, Fan F, Cui Y, Luo X, Tan S, Wang Z, Yang F, Tian B, Li CR, Hong LE, Tan Y. Kynurenine metabolism and metabolic syndrome in patients with schizophrenia. Journal Of Psychiatric Research 2021, 139: 54-61. PMID: 34034146, DOI: 10.1016/j.jpsychires.2021.05.004.Peer-Reviewed Original ResearchConceptsMetabolic syndromeKP metabolitesMS scorePathogenesis of MSKynurenine pathway metabolismRegression analysisKynurenine metabolismPatient groupHealthy controlsMultiple linear regression analysisSchizophrenia patientsLinear regression analysisPathway metabolismPatientsContributory roleSchizophreniaHigh nicotinamide adenine dinucleotideNicotinamide adenine dinucleotideMS factorsPotential rolePartial correlation analysisScoresMultiple regression analysisSyndromePathogenesis