2004
Antiangiogenic therapy Creating a unique “window” of opportunity
Lin M, Sessa W. Antiangiogenic therapy Creating a unique “window” of opportunity. Cancer Cell 2004, 6: 529-531. PMID: 15607955, DOI: 10.1016/j.ccr.2004.12.003.Peer-Reviewed Original ResearchAngiogenesis InhibitorsAngiopoietin-1AnimalsAntibodies, MonoclonalBasement MembraneBlood VesselsCell MovementCollagenasesCombined Modality TherapyGamma RaysGliomaHumansMiceModels, BiologicalNeoplasmsNeovascularization, PathologicPericytesReceptor, TIE-2Time FactorsVascular Endothelial Growth Factor Receptor-2Xenograft Model Antitumor Assays
1999
Codistribution of NOS and caveolin throughout peripheral vasculature and skeletal muscle of hamsters
Segal S, Brett S, Sessa W. Codistribution of NOS and caveolin throughout peripheral vasculature and skeletal muscle of hamsters. American Journal Of Physiology 1999, 277: h1167-h1177. PMID: 10484439, DOI: 10.1152/ajpheart.1999.277.3.h1167.Peer-Reviewed Original ResearchConceptsCaveolin-3Caveolin-1Skeletal muscleCaveolin isoformsCoat proteinCaveolinFunctional interactionIntact organismEnzyme isoformsNitric oxide synthase activitySmooth muscle cellsMuscle fibersOxide synthase activityVascular smooth muscleSynthase activitySkeletal muscle fibersMuscle cellsIsoformsCell systemSystemic vasculatureVena cavaFemoral arteryAbdominal aortaPeripheral vasculatureEndothelial cellsHsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension
Shah V, Wiest R, Garcia-Cardena G, Cadelina G, Groszmann R, Sessa W. Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension. American Journal Of Physiology 1999, 277: g463-g468. PMID: 10444461, DOI: 10.1152/ajpgi.1999.277.2.g463.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholineAnimalsBenzoquinonesBlood VesselsHSP90 Heat-Shock ProteinsHypertension, PortalIn Vitro TechniquesLactams, MacrocyclicMaleMethoxamineMicrocirculationNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type IIIQuinonesRatsRats, Sprague-DawleySplanchnic CirculationTissue DistributionVasoconstrictor AgentsVasodilationVasodilator AgentsConceptsEndothelial nitric oxide synthasePortal vein ligationNitric oxide synthasePortal hypertensionMesenteric vasculatureOxide synthaseNormal animalsACh-dependent vasodilationExperimental portal hypertensionExcessive NO productionNO-dependent responsesNOS catalytic activityDependent vasodilationVein ligationVascular controlMesenteric circulationPVL animalsMesenteric vesselsHeat shock protein 90Sodium nitroprussideNO productionEndothelial liningHypertensionShock protein 90Methoxamine
1998
The hepatic circulation in health and disease: Report of a single‐topic symposium
Shah V, García‐Cardeña G, Sessa W, Groszmann R. The hepatic circulation in health and disease: Report of a single‐topic symposium. Hepatology 1998, 27: 279-288. PMID: 9425948, DOI: 10.1002/hep.510270141.Peer-Reviewed Original Research