2024
Estimating the health effects of COVID-19-related immunisation disruptions in 112 countries during 2020–30: a modelling study
Hartner A, Li X, Echeverria-Londono S, Roth J, Abbas K, Auzenbergs M, de Villiers M, Ferrari M, Fraser K, Fu H, Hallett T, Hinsley W, Jit M, Karachaliou A, Moore S, Nayagam S, Papadopoulos T, Perkins T, Portnoy A, Minh Q, Vynnycky E, Winter A, Burrows H, Chen C, Clapham H, Deshpande A, Hauryski S, Huber J, Jean K, Kim C, Kim J, Koh J, Lopman B, Pitzer V, Tam Y, Lambach P, Sim S, Woodruff K, Ferguson N, Trotter C, Gaythorpe K. Estimating the health effects of COVID-19-related immunisation disruptions in 112 countries during 2020–30: a modelling study. The Lancet Global Health 2024, 12: e563-e571. PMID: 38485425, PMCID: PMC10951961, DOI: 10.1016/s2214-109x(23)00603-4.Peer-Reviewed Original ResearchConceptsCatch-up activitiesVaccine-preventable disease burdenCatch-upVaccine Impact Modelling ConsortiumImmunisation servicesMiddle-income countriesEffectiveness of HPV vaccinationVaccine effectivenessAffected cohortBill & Melinda Gates FoundationImmunisation coverageLow-incomeLong-term effectsWHO-UNICEFDisease burdenVaccination coverageCalendar yearImmunisation effortsMelinda Gates FoundationMitigation measuresCountriesYears of vaccinationYellow fever vaccine
2022
Predicting the long-term impact of rotavirus vaccination in 112 countries from 2006 to 2034: A transmission modeling analysis
Kraay A, Steele M, Baker J, Hall E, Deshpande A, Saidzosa B, Mukaratirwa A, Boula A, Mpabalwani E, Kiulia N, Tsolenyanu E, Enweronu-Laryea C, Abebe A, Beyene B, Tefera M, Willilo R, Batmunkh N, Pastore R, Mwenda J, Antoni S, Cohen A, Pitzer V, Lopman B. Predicting the long-term impact of rotavirus vaccination in 112 countries from 2006 to 2034: A transmission modeling analysis. Vaccine 2022, 40: 6631-6639. PMID: 36210251, PMCID: PMC10351612, DOI: 10.1016/j.vaccine.2022.09.072.Peer-Reviewed Original ResearchMeSH KeywordsCost-Benefit AnalysisGastroenteritisHumansInfantRotavirusRotavirus InfectionsRotavirus VaccinesVaccinationConceptsRotavirus vaccinationRotavirus positivityVaccine introductionOne-dose scheduleTwo-dose seriesRotavirus burdenRotavirus casesRotavirus gastroenteritisHospital admissionMiddle-income countriesVaccine impactVaccinated individualsLong-term impactMortality burdenPercent reductionVaccinationLife yearsIndirect protectionLow-income countriesLong-term magnitudePositivityDeathBurdenYearsIntroduction Data
2016
Strategies to Prevent Cholera Introduction during International Personnel Deployments: A Computational Modeling Analysis Based on the 2010 Haiti Outbreak
Lewnard JA, Antillón M, Gonsalves G, Miller AM, Ko AI, Pitzer VE. Strategies to Prevent Cholera Introduction during International Personnel Deployments: A Computational Modeling Analysis Based on the 2010 Haiti Outbreak. PLOS Medicine 2016, 13: e1001947. PMID: 26812236, PMCID: PMC4727895, DOI: 10.1371/journal.pmed.1001947.Peer-Reviewed Original ResearchConceptsOral cholera vaccineProbability of casesAntimicrobial chemoprophylaxisCholera vaccineOral cholera vaccinationAntimicrobial regimensProphylactic efficacyAsymptomatic carriageCholera vaccinationAsymptomatic carriersIncidence rateLargest cholera epidemicCholera epidemicChemoprophylaxisCholera incidence ratesFalse-positive test outcomesVaccinationFirst weekDiagnostic screeningAntimicrobial chemotherapyHaiti cholera epidemicIntervention strategiesVaccineIndependent panelCholera importationIn-season and out-of-season variation of rotavirus genotype distribution and age of infection across 12 European countries before the introduction of routine vaccination, 2007/08 to 2012/13.
Hungerford D, Vivancos R, Read J, Pitzer V, Cunliffe N, French N, Iturriza-Gómara M. In-season and out-of-season variation of rotavirus genotype distribution and age of infection across 12 European countries before the introduction of routine vaccination, 2007/08 to 2012/13. Eurosurveillance 2016, 21 PMID: 26794258, DOI: 10.2807/1560-7917.es.2016.21.2.30106.Peer-Reviewed Original ResearchConceptsGenotype distributionMultinomial multivariate logistic regressionRotavirus gastroenteritis casesRotavirus genotype distributionRoutine rotavirus vaccinationRotavirus vaccination programRotavirus-positive specimensMultivariate logistic regressionOdds of infectionAge of infectionRVGE casesUntypable genotypesRotavirus vaccinationRoutine vaccinationVaccine introductionVaccination programGastroenteritis casesEpidemiological changesGenotype surveillanceLogistic regressionCommon genotypeMicrobiological dataVaccinationSurveillance networkAge
2015
Did Large-Scale Vaccination Drive Changes in the Circulating Rotavirus Population in Belgium?
Pitzer VE, Bilcke J, Heylen E, Crawford FW, Callens M, De Smet F, Van Ranst M, Zeller M, Matthijnssens J. Did Large-Scale Vaccination Drive Changes in the Circulating Rotavirus Population in Belgium? Scientific Reports 2015, 5: 18585. PMID: 26687288, PMCID: PMC4685644, DOI: 10.1038/srep18585.Peer-Reviewed Original ResearchMeSH KeywordsBelgiumGenotypeHumansModels, TheoreticalRotavirusRotavirus InfectionsRotavirus VaccinesVaccinationConceptsVaccine introductionStrain-specific vaccine effectivenessVaccine-derived immunityRotavirus vaccine introductionVaccine-induced immunityAbsence of vaccinationRotavirus populationLarge-scale vaccinationDistribution of genotypesRotavirus gastroenteritisVaccine effectivenessHomotypic strainHospitalization dataPredominant rotavirusStrain replacementVaccinationVaccineImmunityInfectionViral populationsPopulationGastroenteritisYearsIncidenceRotavirus
2014
Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study
Pitzer VE, Bowles CC, Baker S, Kang G, Balaji V, Farrar JJ, Grenfell BT. Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study. PLOS Neglected Tropical Diseases 2014, 8: e2642. PMID: 24416466, PMCID: PMC3886927, DOI: 10.1371/journal.pntd.0002642.Peer-Reviewed Original ResearchConceptsChristian Medical College HospitalSubstantial indirect protectionMedical College HospitalCulture-confirmed casesImpact of vaccinationIncidence of typhoidTransmission dynamicsOne-time campaignChronic carriersCollege HospitalVaccination strategiesEndemic settingsTyphoid feverVaccinationTyphoid infectionTyphoid casesNatural historyIndirect protectionVi polysaccharideBasic reproductive numberTyphoidIncidenceTyphoid incidenceAge distributionReproductive number
2011
Modeling rotavirus strain dynamics in developed countries to understand the potential impact of vaccination on genotype distributions
Pitzer VE, Patel MM, Lopman BA, Viboud C, Parashar UD, Grenfell BT. Modeling rotavirus strain dynamics in developed countries to understand the potential impact of vaccination on genotype distributions. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 19353-19358. PMID: 22084114, PMCID: PMC3228484, DOI: 10.1073/pnas.1110507108.Peer-Reviewed Original ResearchConceptsHeterotypic immunityCommon rotavirus genotypesPredominance of G1Impact of vaccinationVaccine-type strainsDistribution of genotypesPrevaccination levelsRotavirus incidenceRotavirus genotypesVaccinationGenotype distributionImmunityGenotype patternsRelative prevalenceVaccineIncidenceStrong immunityFrequency of cyclingDisease incidenceGenotypesStrong protectionNew strainG1HomotypicPrevalence