2012
Clonally dominant cardiomyocytes direct heart morphogenesis
Gupta V, Poss KD. Clonally dominant cardiomyocytes direct heart morphogenesis. Nature 2012, 484: 479-484. PMID: 22538609, PMCID: PMC3340018, DOI: 10.1038/nature11045.Peer-Reviewed Original ResearchConceptsStem cell populationVertebrate embryosVertebrate organsNew lineageClonal dominanceEmbryonic structuresClonal analysisTissue architectureCell populationsProliferative behaviorIndividual cardiomyocytesAdult formKey mechanismCardiomyocytesAdult cardiac structureCirculatory needsMorphogenesisLineagesEmbryosMaturesDominanceOrgansVariable sizeThick wallsLateral expansion
2011
tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration
Kikuchi K, Gupta V, Wang J, Holdway JE, Wills AA, Fang Y, Poss KD. tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration. Development 2011, 138: 2895-2902. PMID: 21653610, PMCID: PMC3119303, DOI: 10.1242/dev.067041.Peer-Reviewed Original ResearchConceptsHeart developmentZebrafish heart developmentRecent lineage-tracing studiesLineage-tracing studiesEmbryonic developmentUpstream sequencesHeart regenerationCell typesEpicardial cellsDevelopmental potentialCardiac muscle cellsZebrafishTCF21Muscle cellsPerivascular cellsCellsFateRegenerationCardiogenesisLarvalEpicardial tissueSequenceExpressionDevelopment