2011
C. elegans meg‐1 and meg‐2 differentially interact with nanos family members to either promote or inhibit germ cell proliferation and survival
Kapelle WS, Reinke V. C. elegans meg‐1 and meg‐2 differentially interact with nanos family members to either promote or inhibit germ cell proliferation and survival. Genesis 2011, 49: 380-391. PMID: 21305687, DOI: 10.1002/dvg.20726.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansCaenorhabditis elegans ProteinsCell ProliferationCell SurvivalDisorders of Sex DevelopmentEmbryo, NonmammalianEpistasis, GeneticFemaleGene Expression Regulation, DevelopmentalGerm CellsLuminescent ProteinsMaleRNA InterferenceRNA-Binding ProteinsTime FactorsConceptsGerm cell proliferationMeg 1Germ cellsEmbryonic primordial germ cellsTargeted RNAi screenPrimordial germ cellsCell proliferationGerm cell survivalGerm lineageP granulesRNAi screenLarval stagesMEG 2Cell survivalFamily membersMultiple pathwaysGerm cell degenerationPhenotypeSterilityProliferationOptimal proliferationCellsCell degenerationEmbryogenesisLineages
2002
A Targeted RNAi Screen for Genes Involved in Chromosome Morphogenesis and Nuclear Organization in the Caenorhabditis elegans Germline
Colaiácovo M, Stanfield G, Reddy K, Reinke V, Kim S, Villeneuve A. A Targeted RNAi Screen for Genes Involved in Chromosome Morphogenesis and Nuclear Organization in the Caenorhabditis elegans Germline. Genetics 2002, 162: 113-128. PMID: 12242227, PMCID: PMC1462232, DOI: 10.1093/genetics/162.1.113.Peer-Reviewed Original ResearchConceptsChromosome morphogenesisNuclear organizationRNA interferenceCaenorhabditis elegans germlineFunctional genomic strategiesMeiotic prophase eventsTargeted RNAi screenGene expression surveyDNA microarray technologyGermline phenotypeGermline proliferationMeiosis genesChromosome organizationMitotic growthRNAi screenGenomic strategiesMeiotic progressionMeiotic prophaseExpression profilesMicroarray technologyGermlineGenesMorphogenesisCaenorhabditisProphase