2021
Fibroblasts: Origins, definitions, and functions in health and disease
Plikus MV, Wang X, Sinha S, Forte E, Thompson SM, Herzog EL, Driskell RR, Rosenthal N, Biernaskie J, Horsley V. Fibroblasts: Origins, definitions, and functions in health and disease. Cell 2021, 184: 3852-3872. PMID: 34297930, PMCID: PMC8566693, DOI: 10.1016/j.cell.2021.06.024.Peer-Reviewed Original ResearchConceptsDiverse mesenchymal cellsComplex extracellular matrixCell fateCellular progenyTissue homeostasisCell cycleBiochemical cuesReversible plasticityExtracellular matrixPositional informationMesenchymal cellsSkeletal muscleTissue repairFibrotic disordersFibroblastsLineagesNicheProgenyHomeostasisPhenotypeOrgansFatePlasticityCellsFunction
2008
More than one way to skin . . .
Fuchs E, Horsley V. More than one way to skin . . . Genes & Development 2008, 22: 976-985. PMID: 18413712, PMCID: PMC2732395, DOI: 10.1101/gad.1645908.Peer-Reviewed Original ResearchConceptsStem cellsMultiple signaling networksNormal tissue homeostasisStem cell nicheStem cell populationResident stem cellsEpithelial-mesenchymal interactionsCell populationsCell fateSignaling networksSpecific lineagesTissue homeostasisCell nicheEpithelial stem cellsEpithelial lineageRecent cluesNormal homeostasisEpithelial tissuesLineagesWound repairHomeostasisCellsHair folliclesNicheFate
2007
Reprogramming somatic cells to their embryonic state
Horsley V, Fuchs E. Reprogramming somatic cells to their embryonic state. All Life 2007, 1: 89-93. PMID: 19404413, PMCID: PMC2639841, DOI: 10.2976/1.2757614.Peer-Reviewed Original ResearchES cellsSomatic cellsPluripotent fateStem cellsEmbryonic stem cellsES-like cellsHuman ES cellsCell Stem CellTranscription factorsEmbryonic cellsAdult bodyPluripotent potentialHuman diseasesTypes of cellsEmbryonic stateAbility of scientistsRegenerative medicineEmbryosCellsRegenerative therapyFatePluripotencyLineagesMechanismExpression