Effect of Doxycycline on Progression of Arterial Calcification in the Noninvasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA(3)CT)
Kim T, Kostiuk V, Olson S, Curci J, Matsumura J, Baxter B, Blackwelder W, Terrin M, Guzman R. Effect of Doxycycline on Progression of Arterial Calcification in the Noninvasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA(3)CT). Annals Of Vascular Surgery 2023, 104: 1-9. PMID: 37356652, PMCID: PMC10748791, DOI: 10.1016/j.avsg.2023.06.019.Peer-Reviewed Original ResearchAbdominal Aortic Aneurysm Clinical TrialSerum MMP-3MMP-9 levelsArterial calcificationEffect of doxycyclineNon-invasive treatmentMMP-3Clinical trialsTomography scanMatrix metalloproteinasesSmall aortic aneurysmsArtery calcificationBaseline characteristicsPlacebo armCalcium scoreStudy armsAortic aneurysmPreclinical modelsMean changeAbdominal vesselsPatientsIndividual arteriesMatrix degradingDoxycyclineCalcification