2015
Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil
Ungprasert P, Chowdhary V, Davis M, Makol A. Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil. Lupus 2015, 25: 427-430. PMID: 26537421, DOI: 10.1177/0961203315615221.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusAutoimmune myelofibrosisLupus erythematosusBullous skin lesionsPresenting manifestationPeripheral destructionHematological abnormalitiesSkin lesionsMofetilErythematosusPancytopeniaMyelofibrosisManifestationsLeucopeniaThrombocytopeniaAnemiaGlucocorticoidsLesionsAbnormalities
2014
IgG4‐related (neurologic) disease: diagnostic challenges, clinical clues and expanding spectrum
Flanagan EP, Chowdhary VR, McCarthy JT, Smyrk TC, Chari ST, Kumar N. IgG4‐related (neurologic) disease: diagnostic challenges, clinical clues and expanding spectrum. International Journal Of Rheumatic Diseases 2014, 18: 807-809. PMID: 25307728, DOI: 10.1111/1756-185x.12465.Peer-Reviewed Original ResearchSystemic Inflammatory Response Elicited by Superantigen Destabilizes T Regulatory Cells, Rendering Them Ineffective during Toxic Shock Syndrome
Tilahun AY, Chowdhary VR, David CS, Rajagopalan G. Systemic Inflammatory Response Elicited by Superantigen Destabilizes T Regulatory Cells, Rendering Them Ineffective during Toxic Shock Syndrome. The Journal Of Immunology 2014, 193: 2919-2930. PMID: 25092888, PMCID: PMC4157092, DOI: 10.4049/jimmunol.1400980.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsAntibodiesAntigen-Antibody ComplexEnterotoxinsGlucocorticoid-Induced TNFR-Related ProteinGlucocorticoidsHLA-DR alpha-ChainsHLA-DR beta-ChainsHLA-DR3 AntigenInterferon-gammaInterleukin-17Interleukin-2Lymphocyte ActivationMethicillin-Resistant Staphylococcus aureusMiceMice, TransgenicReceptors, Tumor Necrosis FactorShock, SepticStaphylococcal InfectionsSuperantigensT-Lymphocytes, RegulatoryUp-RegulationConceptsToxic shock syndromeEndogenous TregsRegulatory cellsShock syndromeT cellsGlucocorticoid-induced TNFR family-related receptorCommunity-acquired methicillin-resistant strainsEx vivoHLA-DR3 transgenic miceSerum IFN-γ levelsFailure of TregsSystemic inflammatory responseIL-2/T regulatory (Treg) cellsIFN-γ levelsConventional T cellsLife-threatening infectionsMethicillin-resistant strainsT cell activationS. aureus strainsTreg numbersAdoptive transferIL-17Immune activationInflammatory response