2018
FRI0371 Clinical characteristics and outcome of isolated lupus nephritis
Bugdayli K, Chowdhary V, Crowson C, Zand L, Alexander M, Cornell L. FRI0371 Clinical characteristics and outcome of isolated lupus nephritis. Annals Of The Rheumatic Diseases 2018, 77: 720. DOI: 10.1136/annrheumdis-2018-eular.6053.Peer-Reviewed Original ResearchExtra-renal manifestationsLupus nephritisSystemic lupus erythematosusAntinuclear antibodiesClinical manifestationsEnd-stage renal diseaseStandardised data collection formClass III nephritisPartial renal responseRenal biopsy databasePositive antinuclear antibodyAnti-dsDNA antibodiesMajority of patientsExtractable nuclear antigensImmune complex glomerulonephritisData collection formMean C3SLICC criteriaLast followMycophenolate mofetilRenal involvementRenal transplantClinical characteristicsLaboratory featuresPartial response
2015
AB0539 Risk of Cardiovascular Events in Patients with Cutaneous Lupus Erythematosus: A Population-Based Study
Singh A, Crowson C, Davis M, Maradit-Kremers H, Matteson E, Chowdhary V. AB0539 Risk of Cardiovascular Events in Patients with Cutaneous Lupus Erythematosus: A Population-Based Study. Annals Of The Rheumatic Diseases 2015, 74: 1080. DOI: 10.1136/annrheumdis-2015-eular.4318.Peer-Reviewed Original ResearchCutaneous lupus erythematosusSystemic lupus erythematosusPopulation-based cohortCardiovascular eventsCardiovascular diseaseLupus erythematosusCumulative incidenceRisk factorsDiagnosis of CLESubtypes of CLERisk of CVDPositive antinuclear antibodyIndependent risk factorSex-matched subjectsKaplan-Meier methodMedical record reviewSex-matched cohortChronic inflammatory diseaseSex-matched controlsComplex gene-environment interactionsMedian ESRAntinuclear antibodiesSystemic inflammationRecord reviewMyocardial infarctionTHU0329 Risk of Cancer is not Increased in Patients with Cutaneous Lupus Erythematosus: A Population-Based Study
Singh A, Crowson C, Davis M, Maradit-Kremers H, Matteson E, Chowdhary V. THU0329 Risk of Cancer is not Increased in Patients with Cutaneous Lupus Erythematosus: A Population-Based Study. Annals Of The Rheumatic Diseases 2015, 74: 314. DOI: 10.1136/annrheumdis-2015-eular.4320.Peer-Reviewed Original ResearchCutaneous lupus erythematosusSystemic lupus erythematosusPopulation-based cohortNon-melanoma skin cancerSex-matched subjectsRisk of malignancyLupus erythematosusIndex dateCumulative incidenceDiagnosis of CLESubtypes of CLESkin cancerSystemic immune dysregulationPositive antinuclear antibodyChronic autoimmune diseaseKaplan-Meier methodMedical record reviewSex-matched cohortCLE subjectsImmunomodulatory medicationsMedian ESRCLE patientsDiagnosis dateAntinuclear antibodiesImmune dysregulation
2007
Characterization of haemorrhagic pulmonary capillaritis: another manifestation of Pristane-induced lupus
Chowdhary V, Grande J, Luthra H, David C. Characterization of haemorrhagic pulmonary capillaritis: another manifestation of Pristane-induced lupus. Rheumatology 2007, 46: 1405-1410. PMID: 17576695, DOI: 10.1093/rheumatology/kem117.Peer-Reviewed Original ResearchConceptsAnti-neutrophil cytoplasm antibodiesBronchoalveolar lavagePulmonary capillaritisAntinuclear antibodiesIL-10IL-6IL-4IL-2TNF-alphaIFN-gammaPhosphate-buffered saline injectionEvidence of vasculitisLupus-specific autoantibodiesPristane-induced lupusPristane-injected miceImmune complex depositionSingle intraperitoneal injectionDifferential cell countsPristane injectionAlveolar inflammationCytokine levelsCytoplasm antibodiesLupus lesionsNeutrophil infiltrationEndothelial injury