2023
Polysomnography
Jafari B, Mohsenin V. Polysomnography. 2023, 374-387. DOI: 10.1016/b978-0-12-822963-7.00174-2.Peer-Reviewed Original ResearchMovement disordersREM sleep behavior disorderSleep behavior disorderSleep-disordered breathingArterial oxygen saturationSleep stagesREM sleep stagesLimb electromyogramsCardiorespiratory functionRespiratory effortSleep architectureArousal disorderOxygen saturationChin electromyogramDiagnostic utilityOrgan functionPolysomnographyBehavior disorderOral airflowSleepDisordersEye movementsStage WElectromyogramBreathing
2022
Obstructive Sleep Apnea and Polycystic Ovary Syndrome
Chu Y, Hilbert J, Mohsenin V. Obstructive Sleep Apnea and Polycystic Ovary Syndrome. 2022, 393-409. DOI: 10.1007/978-3-030-92589-5_20.Peer-Reviewed Original ResearchPolycystic ovary syndromeObstructive sleep apneaCardiovascular outcomesOvary syndromeSleep apneaPathogenesis of OSAPrevalence of OSARepetitive upper airway obstructionsUntreated sleep-disordered breathingExcess of androgensUpper airway obstructionImproved cardiovascular outcomesSleep-disordered breathingSleep breathing disordersWeight-matched controlsImproved sleep qualityRates of obesityAirway obstructionNorepinephrine levelsCentral adiposityAtypical symptomsInsulin resistanceTreatment optionsSex hormonesTreatment benefit
2018
Treating Sleep-Related Breathing Disorders
Won C, Mohsenin V, Kryger M. Treating Sleep-Related Breathing Disorders. 2018, 105-123. DOI: 10.1007/978-1-4939-8607-1_9.Peer-Reviewed Original ResearchPositive airway pressure therapySignificant symptomatic benefitAirway pressure therapySleep-disordered breathingMental health outcomesNeuropsychomotor functionsPAP therapyMainstay treatmentSymptomatic benefitPAP adherenceBreathing disordersPressure therapySide effectsHealth outcomesPatientsTherapyEffective alternativeAdherenceRobust evidenceTolerabilityBreathingSleep
2016
Chitinase-3-like protein-1 (YKL-40) as a marker of endothelial dysfunction in obstructive sleep apnea
Jafari B, Mohsenin V. Chitinase-3-like protein-1 (YKL-40) as a marker of endothelial dysfunction in obstructive sleep apnea. Sleep Medicine 2016, 25: 87-92. PMID: 27823723, DOI: 10.1016/j.sleep.2016.08.001.Peer-Reviewed Original ResearchConceptsHypertensive OSAObstructive sleep apneaFlow-mediated vasodilationEndothelial dysfunctionYKL-40Sleep apneaEndothelial-dependent vasodilatory capacityNormotensive OSAChitinase-3-like protein 1Sleep-disordered breathingCharacteristic curve analysisChitinase-3-like proteinHypertension independentVasodilatory capacityCardiovascular morbidityEndothelial functionHypertension statusRisk factorsPrevalent disorderHypertensionNegative correlationDysfunctionPotential biomarkersSignificant negative correlationCurve analysisThe emerging role of microRNAs in hypoxia-induced pulmonary hypertension
Mohsenin V. The emerging role of microRNAs in hypoxia-induced pulmonary hypertension. Sleep And Breathing 2016, 20: 1059-1067. PMID: 27154628, DOI: 10.1007/s11325-016-1351-y.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionHypoxia-induced pulmonary hypertensionPulmonary hypertensionArterial hypertensionHeart failureRole of microRNAsMechanism of PHPulmonary arterial blood pressurePulmonary arterial smooth muscle cellsDevelopment of PHIdiopathic pulmonary arterial hypertensionChronic obstructive lung diseasePathogenesis of PHArterial smooth muscle cellsRight heart failureRight ventricular dysfunctionPoor prognostic signArterial blood pressureCongestive heart failureObstructive lung diseaseSleep-disordered breathingSetting of hypoxiaAberrant vascular remodelingQuality of lifeSmooth muscle cells
2013
Polysomnography
Jafari B, Mohsenin V. Polysomnography. 2013, 465-474. DOI: 10.1016/b978-0-12-378610-4.00352-1.Peer-Reviewed Original Research
2001
Gender Differences in the Expression of Sleep-Disordered Breathing Role of Upper Airway Dimensions
Mohsenin V. Gender Differences in the Expression of Sleep-Disordered Breathing Role of Upper Airway Dimensions. CHEST Journal 2001, 120: 1442-1447. PMID: 11713117, DOI: 10.1378/chest.120.5.1442.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaSleep-disordered breathingUpper airway sizeUpper airway dimensionsSleep apneaAirway sizeMale patientsFemale patientsAirway dimensionsUpper airwayEvaluation of SDBPrevalence of OSAPharyngeal sizeGreater total body fatMild obstructive sleep apneaUpper airway resistance syndromeSevere obstructive sleep apneaPharyngeal muscle toneUpper airway patencyEffect of obesityExcessive daytime sleepinessSimilar clinical presentationUpper airway narrowingDifferent pathogenetic mechanismsMajor risk factor
1999
Quality of Life in Patients with Obstructive Sleep Apnea Effect of Nasal Continuous Positive Airway Pressure—A Prospective Study
D’Ambrosio C, Bowman T, Mohsenin V. Quality of Life in Patients with Obstructive Sleep Apnea Effect of Nasal Continuous Positive Airway Pressure—A Prospective Study. CHEST Journal 1999, 115: 123-129. PMID: 9925072, DOI: 10.1378/chest.115.1.123.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaQuality of lifeMental healthMedical Outcomes Study Short Form-36 questionnaireNasal continuous positive airway pressure treatmentEffect of OSAContinuous positive airway pressure (CPAP) treatmentNasal continuous positive airway pressureDiagnosis of OSASocial functioningPositive airway pressure treatmentContinuous positive airway pressureShort Form-36 questionnaireEffect of nCPAPPositive airway pressureRespiratory disturbance indexSleep-disordered breathingBody mass indexEvents/hGender-matched populationCase series analysisSeverity of diseaseMagnitude of improvementNCPAP levelNCPAP therapy
1995
Sleep apnea in patients with hemispheric stroke
Mohsenin V, Valor R. Sleep apnea in patients with hemispheric stroke. Archives Of Physical Medicine And Rehabilitation 1995, 76: 71-76. PMID: 7811179, DOI: 10.1016/s0003-9993(95)80046-8.Peer-Reviewed Original ResearchConceptsSleep-disordered breathingHemispheric strokeCerebral symptomsSleep apneaStroke patientsRapid eye movement (REM) sleepArterial oxygen desaturationComplications of strokePresence of hypertensionRespiratory disturbance indexBody mass indexAbnormal sleep architectureEye movement sleepSlow-wave sleepOxygen desaturationGroups of subjectsBrainstem lesionsCerebrovascular accidentCerebral strokeMass indexRespiratory disturbancesRespiratory eventsMovement sleepSleep architecturePrior history