2023
Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Metz T, Allshouse A, McMillin G, Greene T, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Silver R. Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function. JAMA 2023, 330: 2191-2199. PMID: 38085313, PMCID: PMC10716715, DOI: 10.1001/jama.2023.21146.Peer-Reviewed Original ResearchConceptsPrimary composite outcomeAdverse pregnancy outcomesComposite outcomeFirst trimesterCannabis exposurePregnancy outcomesCannabis usePlacental functionPropensity score-weighted analysisNulliparous Pregnancy Outcomes StudyOngoing exposureMaternal cannabis useUrine cotinine assayUrine samplesMedical record abstractionPregnancy outcome dataGestational-age birthsBody mass indexGestational age windowsPregnancy Outcomes StudyUS medical centersOngoing cannabis useAdjudication of outcomesMaternal cannabisHypertensive disorders
2014
Association Between Stillbirth and Illicit Drug Use and Smoking During Pregnancy
Varner MW, Silver RM, Hogue C, Willinger M, Parker CB, Thorsten VR, Goldenberg RL, Saade GR, Dudley DJ, Coustan D, Stoll B, Bukowski R, Koch MA, Conway D, Pinar H, Reddy UM. Association Between Stillbirth and Illicit Drug Use and Smoking During Pregnancy. Obstetrics And Gynecology 2014, 123: 113-125. PMID: 24463671, PMCID: PMC3931517, DOI: 10.1097/aog.0000000000000052.Peer-Reviewed Original ResearchConceptsIllicit drug useCotinine assaysDrug useMaternal serum cotinine levelStillbirth Collaborative Research NetworkCannabis useSelf-reported smoking historyRisk of stillbirthLive-birth deliveriesSerum cotinine levelsCase-control studySecond-hand smokeUmbilical cord samplesIllicit drugsDose-response relationshipStillbirth deliverySmoking historyCotinine levelsMaternal serumSerum cotinineBirth deliveryCord homogenateSmoking useCord samplesStillbirth