In vitro sealing of punctured fetal membranes: Potential treatment for midtrimester premature rupture of membranes
Reddy U, Shah S, Nemiroff R, Ballas S, Hyslop T, Chen J, Wapner R, Sciscione A. In vitro sealing of punctured fetal membranes: Potential treatment for midtrimester premature rupture of membranes. American Journal Of Obstetrics And Gynecology 2001, 185: 1090-1093. PMID: 11717639, DOI: 10.1067/mob.2001.117685.Peer-Reviewed Original ResearchConceptsMidtrimester premature ruptureAmniotic fluidPremature ruptureFetal membranesAmniotic membraneSignificant perinatal morbidityPrimary outcome variableSecond trimester pregnancySecond trimester amniotic fluidRank sum testPerinatal morbidityMedian timeTrimester pregnancyPuncture siteEffective treatmentPotential treatmentNeedle punctureOutcome variablesSum test