2024
Pregnancy Outcomes in Women Who Developed Elevated Blood Pressure and Stage I Hypertension after 20 Weeks, Gestation
Woolcock H, Parra N, Zhang Y, Reddy U, Bello N, Miller E, Booker W. Pregnancy Outcomes in Women Who Developed Elevated Blood Pressure and Stage I Hypertension after 20 Weeks, Gestation. American Journal Of Perinatology 2024, 41: 2135-2143. PMID: 38569509, PMCID: PMC11496016, DOI: 10.1055/a-2298-5347.Peer-Reviewed Original ResearchAssociated with adverse pregnancy outcomesFetal growth restrictionPlacental abruptionWeeks gestationBlood pressureElevated BPAmerican Heart AssociationPregnancy outcomesNormal BPOdds of fetal growth restrictionIncreased riskOdds of placental abruptionAmerican CollegeMultivariable-adjusted odds ratioAssociated with HDPAdverse pregnancy outcomesWeeks of pregnancyProspective cohort studyElevated blood pressureConfidence intervalsStage I hypertensionAmerican College of Cardiology (ACCCesarean deliveryPreterm deliverySingleton pregnancies
2023
Sodium intake and the development of hypertensive disorders of pregnancy
Bank T, Grasch J, Chung J, Mercer B, McNeil R, Parry S, Saade G, Shanks A, Silver R, Simhan H, Yee L, Reddy U, Grobman W, Frey H. Sodium intake and the development of hypertensive disorders of pregnancy. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101166. PMID: 37741626, DOI: 10.1016/j.ajogmf.2023.101166.Peer-Reviewed Original ResearchConceptsHypertensive disordersHigh sodium intakeSodium intakeChronic hypertensionNonpregnant populationLow platelet count syndromeNeonatal intensive care unitNulliparous Pregnancy Outcomes StudyElevated liver enzymesGestational age neonatesFood frequency questionnaireLow sodium intakeIncidence risk ratioIntensive care unitWeeks of gestationPregnancy Outcomes StudyLack of associationChi-square testGestational hypertensionNeonatal outcomesNonpregnant stateSodium restrictionFrequency questionnairePreterm birthSingleton pregnanciesCervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix
Hoffman M, Clifton R, Biggio J, Saade G, Ugwu L, Longo M, Bousleiman S, Clark K, Grobman W, Frey H, Chauhan S, Dugoff L, Manuck T, Chien E, Rouse D, Simhan H, Esplin M, Macones G, Bickus M, Facco F, Tita A, Grant J, Casey B, Harris S, Harper L, Dunn D, Longo S, Hendricks M, Lata-Arias K, Costantine M, Bartholomew A, Cline D, Harper S, Ward C, Gardner N, Brindle S, Weigand S, McKenna D, Snow E, Fennig K, Habli M, Lambers D, McClellan M, Metz T, Sowles A, Varner M, Hill K, Morby V, Meadows C, Allard D, Werner E, Rousseau J, Milano J, Pettker C, Leventhal J, Gyamfi-Bannerman C, Wapner R, Carmona V, Firman B, Vanneman A, Palomares K, Beche I, Skupski D, Chan-Akeley R, Salazar A, Pacheco L, McCoy L, Saad A, Jain S, Omere C, Clifford C, McDonnold M, Chien E, Dalton W, Polito L, Milluzi C, Kushner K, Maile A, Bell J, Hackney D, Ortiz F, Timlin S, Goodnight W, Manuck T, Beamon C, Nun H, Eichelberger K, Moore A, Hughes B, Ferrara J, Grobman W, Mallett G, Stein L, Miller E, Plunkett B, Kearns K, Palatnik A, Malone T, Parry S, Pizzi C, Craig J, Filipczak A, Thom E, Doherty L, Hubbard A, Erikson P, Pinto T, Marcharchand P, Reddy U, Miodovnik M, Archer S. Cervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix. JAMA 2023, 330: 340-348. PMID: 37490086, PMCID: PMC10369212, DOI: 10.1001/jama.2023.10812.Peer-Reviewed Original ResearchConceptsCervical pessaryUsual carePreterm birthShort cervixVaginal progesteroneCervical lengthSingleton pregnanciesFetal deathPrimary outcomeInfant deathPrior spontaneous preterm birthTransvaginal ultrasound cervical lengthCervical pessary placementWeeks 0 daysSpontaneous preterm birthUltrasound cervical lengthWeeks 6 daysThird interim analysisNeonatal/infant mortalityPreterm deliverySingleton gestationsBaseline characteristicsUltrasound evidencePessary placementTransvaginal ultrasoundAssociation of maternal body mass index with success and outcomes of attempted operative vaginal delivery
Grasch J, Venkatesh K, Grobman W, Silver R, Saade G, Mercer B, Yee L, Scifres C, Parry S, Simhan H, Reddy U, Frey H. Association of maternal body mass index with success and outcomes of attempted operative vaginal delivery. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101081. PMID: 37422004, DOI: 10.1016/j.ajogmf.2023.101081.Peer-Reviewed Original ResearchConceptsMaternal body mass indexBody mass indexOperative vaginal deliveryVaginal delivery attemptComposite maternal morbidityComposite neonatal morbidityVaginal deliveryMass indexNeonatal morbidityCesarean deliveryMaternal morbidityAdverse outcomesSecond-stage cesarean deliveryBody mass index groupsBody mass index categoriesNulliparous Pregnancy Outcomes StudyNonanomalous singleton pregnanciesNeonatal adverse outcomesMultivariable logistic regressionPregnancy Outcomes StudyNulliparous individualsDose-dependent mannerSecondary outcomesSingleton pregnanciesPrimary outcomeFetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use?
Leon-Martinez D, Lundsberg L, Culhane J, Zhang J, Son M, Reddy U. Fetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use? American Journal Of Obstetrics And Gynecology 2023, 229: 678.e1-678.e16. PMID: 37348779, DOI: 10.1016/j.ajog.2023.06.035.Peer-Reviewed Original ResearchConceptsNeonatal composite outcomeComposite outcomeFetal growth restrictionGestational ageFetal weightWeeks of gestationPositive likelihood ratioGrowth restrictionNonanomalous singleton pregnanciesPoor neonatal outcomeRetrospective cohort studySingle academic centerWeeks of deliveryDays of deliveryFetal growth referencesElectronic medical recordsProportion of fetusesLikelihood ratioNeonatal morbidityNeonatal outcomesPerinatal outcomesCohort studySingleton pregnanciesNeonatal dataMedical records
2017
Neonatal Outcomes by Attempted Mode of Delivery and Obstetric Intervention for Pregnancies Affected by Spina Bifida [19R]
Spiliopoulos M, Iqbal S, Reddy U, Landy H, Huang C. Neonatal Outcomes by Attempted Mode of Delivery and Obstetric Intervention for Pregnancies Affected by Spina Bifida [19R]. Obstetrics And Gynecology 2017, 129: 188s. DOI: 10.1097/01.aog.0000514163.09127.5e.Peer-Reviewed Original ResearchImmediate neonatal outcomeNeonatal outcomesCesarean deliveryMode of deliveryVaginal deliverySpina bifidaInduced laborLabor induction groupRetrospective cohort studyPrevious cesarean deliveryInduction of laborMultivariable logistic regressionWeeks of gestationYears of ageSafe Labor studyNICU admissionCesarean sectionCohort studyRespiratory morbiditySingleton pregnanciesSpontaneous laborBreech deliveryGestational ageObstetric interventionsBirth trauma
2016
Factor V Leiden, prothrombin G20210A, and methylene tetrahydrofolate reductase mutations and stillbirth: the Stillbirth Collaborative Research Network
Silver RM, Saade GR, Thorsten V, Parker CB, Reddy UM, Drews-Botsch C, Conway D, Coustan D, Dudley DJ, Bukowski R, Hogue C, Pinar H, Varner MW, Goldenberg R, Willinger M. Factor V Leiden, prothrombin G20210A, and methylene tetrahydrofolate reductase mutations and stillbirth: the Stillbirth Collaborative Research Network. American Journal Of Obstetrics And Gynecology 2016, 215: 468.e1-468.e17. PMID: 27131585, DOI: 10.1016/j.ajog.2016.04.026.Peer-Reviewed Original ResearchConceptsFactor V LeidenStillbirth Collaborative Research NetworkCase-control studyHeritable thrombophiliaV LeidenProthrombin G20210AFetal thrombophiliaOdds ratioPAI-1 4G/4G polymorphismPopulation-based case-control studyMaternal factor V LeidenHomozygous factor V Leiden mutationFactor V Leiden mutationEvaluation of stillbirthTetrahydrofolate reductase mutationOdds of stillbirthV Leiden mutationTetrahydrofolate reductase C677TCollaborative research networksReductase C677TResearch NetworkMaternal thrombophiliaThrombophilia markersSingleton pregnanciesIncreased odds
2011
Prepregnancy Risk Factors for Antepartum Stillbirth in the United States
Reddy U, Laughon S, Sun L, Troendle J, Willinger M, Zhang J. Prepregnancy Risk Factors for Antepartum Stillbirth in the United States. Obstetrical & Gynecological Survey 2011, 66: 69-70. DOI: 10.1097/ogx.0b013e31821686c6.Peer-Reviewed Original ResearchPrepregnancy risk factorsAntepartum stillbirthBody mass indexRisk factorsAdvanced maternal ageChronic hypertensionTerm stillbirthMaternal ageMass indexPrepregnancy body mass indexLive birth controlsRisk of stillbirthWeeks of gestationAfrican American racePotential risk factorsIndividual risk factorsYears of ageAdjusted riskAntenatal surveillanceCesarean deliveryPreterm birthSingleton pregnanciesPreexisting diabetesTerm deliveryNormal weight
2010
Pregnancy Outcomes in Infertile Couples
Signore C, Reddy U. Pregnancy Outcomes in Infertile Couples. 2010, 715-725. DOI: 10.1007/978-1-4419-1436-1_49.Peer-Reviewed Original ResearchAssisted Reproductive TechnologyART pregnanciesHigh riskLong-term child healthReasonable pregnancy ratesSingleton ART pregnanciesNumber of embryosPerinatal outcomesMultiple gestationsPregnancy outcomesSingleton pregnanciesAdverse outcomesART mothersObserved complicationsHealthy childrenInfertility treatmentPregnancy rateInfertile couplesChild healthPregnancyReproductive technologiesDevelopmental problemsComplicationsOutcomesRecent data