2023
Randomized Trial of Hyperimmune Globulin for Congenital CMV Infection — 2-Year Outcomes
Hughes B, Clifton R, Rouse D, Saade G, Dinsmoor M, Reddy U, Pass R, Allard D, Mallett G, MacPherson C, Wapner R, Metz T, Goodnight W, Tita A, Costantine M, Swamy G, Heyborne K, Chien E, Chauhan S, El-Sayed Y, Casey B, Parry S, Simhan H, Napolitano P, Macones G. Randomized Trial of Hyperimmune Globulin for Congenital CMV Infection — 2-Year Outcomes. New England Journal Of Medicine 2023, 389: 1822-1824. PMID: 37937785, PMCID: PMC10683876, DOI: 10.1056/nejmc2308286.Peer-Reviewed Original ResearchDesirability of outcome ranking for obstetrical trials: illustration and application to the ARRIVE trial
SANDOVAL G, GROBMAN W, EVANS S, RICE M, CLIFTON R, CHAUHAN S, COSTANTINE M, GIBSON K, LONGO M, METZ T, MILLER E, PARRY S, REDDY U, ROUSE D, SIMHAN H, THORP J, TITA A, SAADE G, Network E. Desirability of outcome ranking for obstetrical trials: illustration and application to the ARRIVE trial. American Journal Of Obstetrics And Gynecology 2023, 230: 370.e1-370.e12. PMID: 37741532, PMCID: PMC10939984, DOI: 10.1016/j.ajog.2023.09.016.Peer-Reviewed Original ResearchElective inductionARRIVE trialCesarean deliverySecondary outcomesPrimary outcomeVaginal deliveryDesirability of outcomeEunice Kennedy Shriver National InstituteSpontaneous vaginal deliverySevere neonatal complicationsWeeks of gestationOperative vaginal deliveryBetter overall outcomesPerson-centred careNeonatal complicationsObstetric trialsExpectant managementPerinatal deathRandomized trialsDecreased riskPoor outcomeClinical trialsChild healthTreatment scoresOutcome rankingsPROMPT: Prospective Meta-analysis for Pessary Trials Study Protocol
Thom E, Saade G, Askie L, Ugwu L, Mol B, Vayssiere C, Norman J, Pajkrt E, Clifton R, Biggio J, Arnaud C, Berghella V, Canino M, Carreras E, Dugoff L, Hoffman M, Pacagnella R, Reddy U, Saccone G, van 't Hooft J, Dang V, Collaboration F. PROMPT: Prospective Meta-analysis for Pessary Trials Study Protocol. American Journal Of Perinatology 2023, 41: e2230-e2237. PMID: 37429323, PMCID: PMC10776795, DOI: 10.1055/s-0043-1771018.Peer-Reviewed Original ResearchShort cervical lengthPreterm birthIndividual patient dataShort cervixRandomized trialsPessary trialCervical lengthTwin gestationsSubsequent spontaneous preterm birthLong-term neurological disabilityOngoing randomized trialsSpontaneous preterm birthTrial study protocolWeeks of gestationProspective Meta-AnalysisSignificant health issueCervical supportNeonatal morbidityPreterm deliverySingleton gestationsSecondary outcomesFetal deathNeurological disabilityPrimary outcomeWeeks' gestation
2015
A Randomized Trial of Intrapartum Fetal ECG ST-Segment Analysis
Belfort M, Saade G, Thom E, Blackwell S, Reddy U, Thorp J, Tita A, Miller R, Peaceman A, McKenna D, Chien E, Rouse D, Gibbs R, El-Sayed Y, Sorokin Y, Caritis S, VanDorsten J. A Randomized Trial of Intrapartum Fetal ECG ST-Segment Analysis. Obstetrical & Gynecological Survey 2015, 70: 735-737. DOI: 10.1097/ogx.0000000000000276.Peer-Reviewed Original ResearchST-segment analysisFetal ECG ST segment analysisElectronic fetal monitoringApgar scoreCesarean deliveryNeonatal encephalopathyOperative deliveryPrimary outcomeVaginal deliveryRandomized trialsOpen groupElectronic fetal heart rate monitorMasked groupElectronic fetal heart rate monitoringFetal heart rate patternsUmbilical artery blood pHContinuous electronic fetal monitoringIntrapartum fetal deathFetal heart rate monitoringPrimary study outcomeOperative vaginal deliveryWeeks of gestationHeart rate patternsSignificant differencesFetal heart rate monitor