Lethal(2)giant larvae is required in the follicle cells for formation of the initial AP asymmetry and the oocyte polarity during Drosophila oogenesis
Li Q, Xin T, Chen W, Zhu M, Li M. Lethal(2)giant larvae is required in the follicle cells for formation of the initial AP asymmetry and the oocyte polarity during Drosophila oogenesis. Cell Research 2008, 18: 372-384. PMID: 18268543, DOI: 10.1038/cr.2008.25.Peer-Reviewed Original ResearchConceptsPosterior follicle cellsFollicle cellsOocyte polarityStalk cellsDrosophila tumor suppressor geneFLP/FRT systemSomatic follicle cellsDrosophila egg developmentTumor suppressor geneDrosophila oogenesisDV axesEgg chambersLgl functionEarly oogenesisFRT systemDorsoventral axesCell lineagesPosterior cellsAnteroposterior asymmetryRegulated differentiationSuppressor geneFunction mutationsPosterior localizationEgg developmentSpecific functions