Effects of Testosterone Treatment in Older Men
Snyder PJ, Bhasin S, Cunningham GR, Matsumoto AM, Stephens-Shields AJ, Cauley JA, Gill TM, Barrett-Connor E, Swerdloff RS, Wang C, Ensrud KE, Lewis CE, Farrar JT, Cella D, Rosen RC, Pahor M, Crandall JP, Molitch ME, Cifelli D, Dougar D, Fluharty L, Resnick SM, Storer TW, Anton S, Basaria S, Diem SJ, Hou X, Mohler ER, Parsons JK, Wenger NK, Zeldow B, Landis JR, Ellenberg SS. Effects of Testosterone Treatment in Older Men. New England Journal Of Medicine 2016, 374: 611-624. PMID: 26886521, PMCID: PMC5209754, DOI: 10.1056/nejmoa1506119.Peer-Reviewed Original ResearchMeSH KeywordsAgedDepressionDouble-Blind MethodFatigueHormone Replacement TherapyHumansLibidoMaleProstate-Specific AntigenReference ValuesSexual BehaviorTestosteroneWalkingConceptsMid-normal rangeMen 65 yearsSerum testosterone concentrationsYears of ageTestosterone treatmentTestosterone levelsTestosterone concentrationsMen 19Depressive symptomsOlder menChronic Illness Therapy-Fatigue ScalePsychosexual Daily QuestionnaireSerum testosterone levelsPercentage of menAdverse eventsErectile functionPrimary outcomePlacebo gelSexual functionStudy groupWalking distanceFunctional assessmentMen ageModerate benefitDaily questionnaires