2016
Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study)
Gill TM, Pahor M, Guralnik JM, McDermott MM, King AC, Buford TW, Strotmeyer ES, Nelson ME, Sink KM, Demons JL, Kashaf SS, Walkup MP, Miller ME. Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study). The BMJ 2016, 352: i245. PMID: 26842425, PMCID: PMC4772786, DOI: 10.1136/bmj.i245.Peer-Reviewed Original ResearchConceptsSerious fall injuriesPhysical activity programHealth education programsStructured physical activity programSedentary older peopleFall injuriesHospital admissionFunctional limitationsActivity programOlder peopleModerate-intensity physical activity programShort Physical Performance Battery scorePhysical Performance Battery scoreNon-vertebral fracturesPrespecified secondary outcomesPhysical activity groupRelated hospital admissionsHealth education groupStructured physical activityBalance training activitiesRate of fallSecondary outcomesStretching exercisesIntervention assignmentClinical trials
2014
Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial
Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD. Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial. JAMA 2014, 311: 2387-2396. PMID: 24866862, PMCID: PMC4266388, DOI: 10.1001/jama.2014.5616.Peer-Reviewed Original ResearchConceptsMajor mobility disabilityPhysical activity groupModerate-intensity physical activity programHealth education groupPhysical activity programHealth education programsMobility disabilityOlder adultsActivity programClinical trialsActivity groupPhysical activityIncident major mobility disabilityShort Physical Performance BatteryPersistent mobility disabilityPhysical activity preventsEducation groupSerious adverse eventsIndependent risk factorPhysical Performance BatteryDefinitive clinical trialsStructured physical activityVulnerable older adultsAdverse eventsLifestyle intervention