2021
Synaptic recognition molecules in development and disease
Chowdhury D, Watters K, Biederer T. Synaptic recognition molecules in development and disease. Current Topics In Developmental Biology 2021, 142: 319-370. PMID: 33706921, PMCID: PMC8632550, DOI: 10.1016/bs.ctdb.2020.12.009.ChaptersConceptsSingle-cell expression studiesRecognition moleculesRecognition factorsKey protein familiesPost-translational modificationsLeucine-rich repeatsCell expression studiesSemaphorin/PlexinAlternative splicingProtein familyProteomic approachCombinatorial actionMolecular playersPartner recognitionExpression studiesMolecular themesSpecific expressionDisease relevanceSynapse specificationVertebrate brainImmunoglobulin SuperfamilyRich repertoireAppropriate brain regionsNeuron type-specific expressionSynaptic wiring
2007
SynCAMs Organize Synapses through Heterophilic Adhesion
Fogel AI, Akins MR, Krupp AJ, Stagi M, Stein V, Biederer T. SynCAMs Organize Synapses through Heterophilic Adhesion. Journal Of Neuroscience 2007, 27: 12516-12530. PMID: 18003830, PMCID: PMC6673342, DOI: 10.1523/jneurosci.2739-07.2007.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell AdhesionCell Adhesion MoleculesCell Adhesion Molecules, NeuronalCell DifferentiationCell LineCells, CulturedCoculture TechniquesHippocampusHumansImmunoglobulinsMacromolecular SubstancesMiceNeural PathwaysPresynaptic TerminalsProtein IsoformsRatsRats, Sprague-DawleySynapsesSynaptic MembranesSynaptic TransmissionTumor Suppressor ProteinsConceptsAdhesion complexesDivergent expression profilesImmunoglobulin superfamily memberHeterophilic complexesProtein familyPosttranslational modificationsHeterophilic adhesionSuperfamily membersCell adhesion moleculeSynapse organizationExpression profilesSynapse developmentSynCAM 1Cell junctionsActive presynaptic terminalsPostsynaptic sideMolecular compositionAdhesion moleculesAdhesive patternsProteinSynaptic cleftPresynaptic terminalsComplexesExcitatory neurotransmissionFunctional synapses