2000
Clinical Measurement, Statistical Analysis, and Risk-Benefit: Controversies from Trials of Spinal Injury
Bracken M, Aldrich E, Herr D, Hitchon P, Holford T, Marshall L, Nockels R, Pascale V, Shepard M, Sonntag V, Winn H, Young W. Clinical Measurement, Statistical Analysis, and Risk-Benefit: Controversies from Trials of Spinal Injury. Journal Of Trauma And Acute Care Surgery 2000, 48: 558-561. PMID: 10744306, DOI: 10.1097/00005373-200003000-00036.Commentaries, Editorials and LettersConceptsNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudyAcute spinal cord injurySpinal Cord Injury StudyClinical measurementsHigh-dose methylprednisoloneSecondary neuronal damageSpinal cord injuryRisk benefitNeuronal damageFunctional recoverySafety profileCord injuryPharmacologic agentsSpinal injuryInjury studiesInnovative therapiesTrialsStatistical analysisInjuryMulticenterMethylprednisoloneSeries of trialsTherapyPrevention
1999
A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
Inouye S, Bogardus S, Charpentier P, Leo-Summers L, Acampora D, Holford T, Cooney L. A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients. New England Journal Of Medicine 1999, 340: 669-676. PMID: 10053175, DOI: 10.1056/nejm199903043400901.Peer-Reviewed Original ResearchConceptsSeverity of deliriumRisk factorsCognitive impairmentRecurrence rateIntervention groupRisk factor intervention strategyHearing impairmentVisual impairmentHospitalized Older PatientsPatients 70 yearsPrevention of deliriumUsual care unitsUsual care groupGeneral medicine serviceEffective treatment strategiesDuration of episodesPrevent DeliriumOlder patientsRate of usePrimary outcomeSleep medicationPoor outcomePrimary preventionPatient's deliriumTeaching hospital