1990
A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury
Bracken M, Shepard M, Collins W, Holford T, Young W, Baskin D, Eisenberg H, Flamm E, Leo-Summers L, Maroon J, Marshall L, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H. A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury. New England Journal Of Medicine 1990, 322: 1405-1411. PMID: 2278545, DOI: 10.1056/nejm199005173222001.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryNeurologic recoverySafety of methylprednisoloneSystematic neurological examinationPlacebo-controlled trialHours of injuryMajor morbidityNeurologic outcomeControlled TrialsNeurological examinationIncomplete lesionsMotor functionMethylprednisoloneNaloxonePatientsBody weightSensory functionInjuryPlaceboInfusionBolusEffective remainsTreatmentDose
1982
Effect of age at first childbirth on risk of developing specific histologic subtype of breast cancer
Livolsi V, Kelsey J, Fischer D, Holford T, Mostow E, Goldenberg I. Effect of age at first childbirth on risk of developing specific histologic subtype of breast cancer. Cancer 1982, 49: 1937-1940. PMID: 6280850, DOI: 10.1002/1097-0142(19820501)49:9<1937::aid-cncr2820490931>3.0.co;2-h.Peer-Reviewed Original ResearchConceptsBreast cancerRisk factorsHistologic subtypeLobular carcinomaSpecific histologic subtypesBenign breast diseaseBreast cancer riskCase-control studyFirst childLater ageVariety of cancersPostmenopausal womenDuct cancerEffect of ageNulliparous womenDuctal carcinomaHistopathologic subtypeEpidemiologic variablesLobular tumorsBreast diseaseBreast carcinomaFamily historyCancer riskBody weightComparison women