2020
Risk factors for recurrent tuberculosis after successful treatment in a high burden setting: a cohort study
Cudahy PGT, Wilson D, Cohen T. Risk factors for recurrent tuberculosis after successful treatment in a high burden setting: a cohort study. BMC Infectious Diseases 2020, 20: 789. PMID: 33097000, PMCID: PMC7585300, DOI: 10.1186/s12879-020-05515-4.Peer-Reviewed Original ResearchConceptsM. tuberculosis infectionRecurrent tuberculosisSuccessful treatmentTuberculosis recurrenceHazard ratioSmear gradeTuberculosis infectionRisk factorsSmear-positive pulmonary tuberculosisCox proportional hazards modelSputum smear gradeRepetitive unit-variable number tandem repeat (MIRU-VNTR) typingHigh-burden settingsRisk of recurrenceProportional hazards modelSuccessful treatment completionRecurrent diseaseCohort studyPulmonary tuberculosisBurden settingsClinical presentationRecurrent episodesInitial episodeNumber tandem repeat typingTreatment completion
2019
Evaluating strategies for control of tuberculosis in prisons and prevention of spillover into communities: An observational and modeling study from Brazil
Mabud TS, de Lourdes Delgado Alves M, Ko AI, Basu S, Walter KS, Cohen T, Mathema B, Colijn C, Lemos E, Croda J, Andrews JR. Evaluating strategies for control of tuberculosis in prisons and prevention of spillover into communities: An observational and modeling study from Brazil. PLOS Medicine 2019, 16: e1002737. PMID: 30677013, PMCID: PMC6345418, DOI: 10.1371/journal.pmed.1002737.Peer-Reviewed Original ResearchConceptsIncidence of TBPrison-based interventionsTB incidenceGeneral populationTB casesCox proportional hazards modelNew TB casesControl of tuberculosisProportional hazards modelPaucity of dataTime of incarcerationTB burdenTB screeningTB riskTB transmissionTB ratesTB epidemicAdministrative databasesCommunity incidenceTuberculosis epidemicHazards modelTB databaseIncidenceEpidemiological contextIntervention
2013
HIV burden in men who have sex with men: a prospective cohort study during 2007–12 in Beijing, China
Jia Z, Huang X, Wu H, Li N, Li Q, Liu Z, Cohen T, Mayer K, Dye C, Salomon J. HIV burden in men who have sex with men: a prospective cohort study during 2007–12 in Beijing, China. The Lancet 2013, 382: s19. DOI: 10.1016/s0140-6736(13)62267-9.Peer-Reviewed Original ResearchProspective cohort studyHIV infectionCondom useCasual partnershipsSteady partnershipsCohort studyHIV antibodiesHIV incidenceDisease burdenPrevalent casesStudy participantsCox proportional hazards modelLower HIV incidenceHIV-negative MSMProportional hazards modelConsistent condom useSexual behaviorSelf-reported condom useSpread of HIVPrevious serological testsUse of condomsLeast high school educationMost study participantsFinal visitBaseline visit
2010
Development of Extensively Drug-resistant Tuberculosis during Multidrug-resistant Tuberculosis Treatment
Shin SS, Keshavjee S, Gelmanova IY, Atwood S, Franke MF, Mishustin SP, Strelis AK, Andreev YG, Pasechnikov AD, Barnashov A, Tonkel TP, Cohen T. Development of Extensively Drug-resistant Tuberculosis during Multidrug-resistant Tuberculosis Treatment. American Journal Of Respiratory And Critical Care Medicine 2010, 182: 426-432. PMID: 20413630, PMCID: PMC2921603, DOI: 10.1164/rccm.200911-1768oc.Peer-Reviewed Original ResearchConceptsMDR-TB treatmentXDR-TBDrug-resistant tuberculosisMultidrug-resistant (MDR) TBMDR-TB treatment programmeExtensively Drug-Resistant TuberculosisMultidrug-resistant tuberculosis treatmentCox proportional hazards modelDevelopment of XDRMDR-TB therapyTB treatment servicesAmplification of resistanceProportional hazards modelThreefold increaseMDR-TBCavitary lesionsConsecutive patientsAppropriate therapyClinical outcomesTreatment adherenceTuberculosis treatmentInjectable antibioticsTimely initiationPrescribed drugsRetrospective analysis