The Impact of Realistic Age Structure in Simple Models of Tuberculosis Transmission
Brooks-Pollock E, Cohen T, Murray M. The Impact of Realistic Age Structure in Simple Models of Tuberculosis Transmission. PLOS ONE 2010, 5: e8479. PMID: 20062531, PMCID: PMC2797602, DOI: 10.1371/journal.pone.0008479.Peer-Reviewed Original ResearchConceptsSimple modelReproductive ratioRealistic age structureSteady-state dynamicsBasic reproductive ratioMathematical descriptionMathematical modelParameter estimationRepresentative of modelsAnalytic argumentsInterpretation of modelsTuberculosis transmissionModelling assumptionsTB modelControl interventionsTB natural historyChronic infectious diseaseDisease dynamicsPublic health interventionsRealistic distributionExponential lifetimesAsymptomatic latent infectionIndividual-based modelPrevalence of infectionActive disease